Upstream toward the “DRiP”-ing Source of the MHC Class I Pathway

MHC class I binding peptides are generated via cytosolic degradation of a previously undefined substrate. In this issue of Immunity, Kunisawa and Shastri (2006) isolate pre-degradation polypeptide intermediates bound to a cytosolic chaperone

Threshold meson production and cosmic ray transport

An interesting accident of nature is that the peak of the cosmic ray spectrum, for both protons and heavier nuclei, occurs near the pion production threshold. The Boltzmann transport equation contains a term which is the cosmic ray flux multiplied by the cross section. Therefore when considering pion and kaon production from proton-proton reactions, small cross sections at low energy can be as important as larger cross sections at higher energy. This is also true for subthreshold kaon production in nuclear collisions, but not for subthreshold pion production.Comment: 9 pages, 1 figur

Comparison of Space Radiation GCR Models to Recent AMS Data

This paper is the third in a series of comparisons of American (NASA) and Russian (ROSCOSMOS) space radiation calculations. The present work focuses on calculation of fluxes of galactic cosmic rays (GCR), which are a constant source of radiation that constitutes one of the major hazards during deep space exploration missions for both astronauts/cosmonauts and hardware. In this work, commonly used GCR models are compared with recently published measurements of cosmic ray Hydrogen, Helium, and the Boron-to-Carbon ratio from the Alpha Magnetic Spectrometer (AMS). All of the models were developed and calibrated prior to the publication of the AMS data, therefore this an opportunity to validate the models against an independent data set

Comparison of Space Radiation GCR Models to AMS Heavy Ion Data

Galactic cosmic rays (GCR) are a constant source of radiation that constitutes one of the major hazards during deep space exploration missions for both astronauts and hardware. In this work, GCR models commonly used by the space radiation protection community are compared with recently published high-precision, high- resolution measurements of cosmic ray lithium, beryllium, boron, carbon, nitrogen, and oxygen fluxes along with their ratios (Li/B, Li/C, Li/O, Be/B, Be/C, Be/O, B/C, B/O, C/O, N/B, N/O) from the Alpha Magnetic Spectrometer (AMS). All of the models were developed and calibrated prior to the publication of this AMS data, therefore this is an opportunity to validate the models against an independent data set. This paper is a compliment to the previously published comparison of GCR models with AMS hydrogen, helium, and the boron-to-carbon ratio

The relationship between group identification and satisfaction with life in a cross-cultural community sample

A variety of studies have shown that group identification (a sense of belonging to one’s social group, coupled with a sense of commonality with the group’s members) is linked to high levels of satisfaction with life (SWL). The aim of the present study was to support and extend this literature by: i) investigating the link between group identification and SWL with a large cross-cultural community sample; ii) examining whether the relationship is moderated by nationality; and iii) considering whether SWL is enhanced by possessing multiple group identifications simultaneously. Utilizing data from Wave 1 of the Health in Groups project, 3,829 participants from both Scotland and Italy completed a questionnaire assessing their identification with their family, their local community, and a group of their choice, as well as their level of SWL. Higher identification with each group predicted higher SWL. Nationality was a marginal moderator of the relationship between family identification and SWL, with the relationship being stronger for Italian participants than for Scottish participants. There was also an additive effect of group identification, with a positive relationship between the number of groups with which participants identified and their SWL. These effects were obtained even after controlling for gender, age, employment status, nationality, and extent of contact with each group. The implications for healthcare professionals and their patients are discussed

Relativistic Multiple Scattering Theory and the Relativistic Impulse Approximation

It is shown that a relativistic multiple scattering theory for hadron-nucleus scattering can be consistently formulated in four-dimensions in the context of meson exchange. We give a multiple scattering series for the optical potential and discuss the differences between the relativistic and non-relativistic versions. We develop the relativistic multiple scattering series by separating out the one boson exchange term from the rest of the Feynman series. However this particular separation is not absolutely necessary and we discuss how to include other terms. We then show how to make a three-dimensional reduction for hadron-nucleus scattering calculations and we find that the relative energy prescription used in the elastic scattering equation should be consistent with the one used in the free two-body t-matrix involved in the optical potential. We also discuss what assumptions are involved in making a Dirac Relativistic Impulse Approximation (RIA).Comment: 20 pages, 9 figures, Accepted for publication in Journal of Physics

Another exact inflationary solution

A new closed-form inflationary solution is given for a hyperbolic interaction potential. The method used to arrive at this solution is outlined as it appears possible to generate additional sets of equations which satisfy the model. In addition a new form of decaying cosmological constant is presented.Comment: 10 pages, 0 figure

Working with simple machines

A set of examples is provided that illustrate the use of work as applied to simple machines. The ramp, pulley, lever and hydraulic press are common experiences in the life of a student and their theoretical analysis therefore makes the abstract concept of work more real. The mechanical advantage of each of these systems is also discussed so that students can evaluate their usefulness as machines.Comment: 9 pages, 4 figure

Exclusive Production of Higgs Bosons in Hadron Colliders

We study the exclusive, double--diffractive production of the Standard Model Higgs particle in hadronic collisions at LHC and FNAL (upgraded) energies. Such a mechanism would provide an exceptionally clean signal for experimental detection in which the usual penalty for triggering on the rare decays of the Higgs could be avoided. In addition, because of the color singlet nature of the hard interaction, factorization is expected to be preserved, allowing the cross--section to be related to similar hard--diffractive events at HERA. Starting from a Fock state expansion in perturbative QCD, we obtain an estimate for the cross section in terms of the gluon structure functions squared of the colliding hadrons. Unfortunately, our estimates yield a production rate well below what is likely to be experimentally feasible.Comment: 17 pages, RevTeX file, four uufiled PostScript figures. UMPP #94-177. (Revised version. Some mistakenly missing Feynman diagrams are now added. Results do not change qualitatively. Paper reorganized.