Power system static and dynamic security studies for the 1st phase of Crete Island Interconnection

The island of Crete is currently served by an autonomous electrical system being fed by oil-fired (Heavy fuel or light Diesel oil) thermal power plants and renewables (wind and PVs). The peak load and annual electric energy consumption are approximately 600 MW and 3 TWh respectively; wind and photovoltaic parks contribute approximately 20% of the electricity needs of the island. Due to the expensive fuel used, the Cretan power system has very high electric energy generation cost compared to the Greek mainland. On the other side the limited size of the system poses severe limitations to the penetration of renewable energy sources, not allowing to further exploit the high wind and solar potential of the island. According to the Ten Year Network Development Plan (TYNDP) of the Greek TSO (Independent Power Transmission Operator S.A. IPTO S.A.), the interconnection of Crete to the mainland Transmission System of Greece will be realized through two links: A 150 kV HVAC link between the Peloponnese and the Crete (Phase I) and a HVDC link connecting the metropolitan area of Athens with Crete (Phase II). The total length of submarine and underground cable of the HVAC link will be approximately 174km; it is at the limits of the AC technology and the longest and deepest worldwide at 150 kV level. A number of studies have been conducted by a joint group of IPTO and Hellenic Electricity Distribution Network Operator (HEDNO) for the design of this interconnection. This paper presents briefly the power system static and dynamic studies conducted for the design of the AC link and its operation. Firstly, the paper presents the main results of the static security study regarding the calculation of the maximum power transfer capability of the link and the selection of the reactive power compensation scheme of the cable. Results from dynamic security analysis studies are also presented. The small-signal stability analysis concludes that a new (intra-area) electromechanical oscillation is introduced to the National System after the interconnection. The damping of the electromechanical oscillations is sufficient; however the operation of power system stabilizers at power plants located both at the mainland and at Crete power system can increase significantly the damping of important oscillation modes. Finally with respect to the risk of loss of synchronism after a significant disturbance in the system of Crete, such as a three-phase fault (“transient stability”)- enough safety margin is estimated by means of Critical Clearing Time calculations

Power system static and dynamic security studies for the 1st phase of Crete Island Interconnection

The island of Crete is currently served by an autonomous electrical system being fed by oil-fired (Heavy fuel or light Diesel oil) thermal power plants and renewables (wind and PVs). The peak load and annual electric energy consumption are approximately 600 MW and 3 TWh respectively; wind and photovoltaic parks contribute approximately 20% of the electricity needs of the island. Due to the expensive fuel used, the Cretan power system has very high electric energy generation cost compared to the Greek mainland. On the other side the limited size of the system poses severe limitations to the penetration of renewable energy sources, not allowing to further exploit the high wind and solar potential of the island. According to the Ten Year Network Development Plan (TYNDP) of the Greek TSO (Independent Power Transmission Operator S.A. IPTO S.A.), the interconnection of Crete to the mainland Transmission System of Greece will be realized through two links: A 150 kV HVAC link between the Peloponnese and the Crete (Phase I) and a HVDC link connecting the metropolitan area of Athens with Crete (Phase II). The total length of submarine and underground cable of the HVAC link will be approximately 174km; it is at the limits of the AC technology and the longest and deepest worldwide at 150 kV level. A number of studies have been conducted by a joint group of IPTO and Hellenic Electricity Distribution Network Operator (HEDNO) for the design of this interconnection. This paper presents briefly the power system static and dynamic studies conducted for the design of the AC link and its operation. Firstly, the paper presents the main results of the static security study regarding the calculation of the maximum power transfer capability of the link and the selection of the reactive power compensation scheme of the cable. Results from dynamic security analysis studies are also presented. The small-signal stability analysis concludes that a new (intra-area) electromechanical oscillation is introduced to the National System after the interconnection. The damping of the electromechanical oscillations is sufficient; however the operation of power system stabilizers at power plants located both at the mainland and at Crete power system can increase significantly the damping of important oscillation modes. Finally with respect to the risk of loss of synchronism after a significant disturbance in the system of Crete, such as a three-phase fault (“transient stability”)- enough safety margin is estimated by means of Critical Clearing Time calculations

Multivariate statistical process control based on principal component analysis: implementation of framework in R

The interest in multivariate statistical process control (MSPC) has increased as the industrial processes have become more complex. This paper presents an industrial process involving a plastic part in which, due to the number of correlated variables, the inversion of the covariance matrix becomes impossible, and the classical MSPC cannot be used to identify physical aspects that explain the causes of variation or to increase the knowledge about the process behaviour. In order to solve this problem, a Multivariate Statistical Process Control based on Principal Component Analysis (MSPC-PCA) approach was used and an R code was developed to implement it according some commercial software used for this purpose, namely the ProMV (c) 2016 from ProSensus, Inc. (www.prosensus.ca). Based on used dataset, it was possible to illustrate the principles of MSPC-PCA. This work intends to illustrate the implementation of MSPC-PCA in R step by step, to help the user community of R to be able to perform it.FCT - Fundação para a Ciência e a Tecnologia(UID/CEC/00319/2013

Microclimate monitoring in the Carcer Tullianum: temporal and spatial correlation and gradients evidenced by multivariate analysis; first campaign

Too often microclimate studies in the field of cultural heritage are published without any or scarce information on sampling design, sensors (type, number, position) and instrument validation. Lacking of this fundamental information does not allow an open discussion in the scientific community. This work aims to be an invitation for a different approach

Spectral Graph Analysis for Process Monitoring

Process monitoring is a fundamental task to support operator decisions under ab- normal situations. Most process monitoring approaches, such as Principal Components Analysis and Locality Preserving Projections, are based on dimensionality reduction. In this paper Spectral Graph Analysis Monitoring (SGAM) is introduced. SGAM is a new process monitoring technique that does not require dimensionality reduction techniques. The approach it is based on the spectral graph analysis theory. Firstly, a weighted graph representation of process measurements is developed. Secondly, the process behavior is parameterized by means of graph spectral features, in particular the graph algebraic connectivity and the graph spectral energy. The developed methodology has been illustrated in autocorrelated and non-linear synthetic cases, and applied to the well known Tennessee Eastman process benchmark with promising results.Fil: Musulin, Estanislao. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Rosario. Centro Internacional Franco Argentino de Ciencias de la Información y Sistemas; Argentin

Membrane testosterone binding sites in prostate carcinoma as a potential new marker and therapeutic target: Study in paraffin tissue sections

BACKGROUND: Steroid action is mediated, in addition to classical intracellular receptors, by recently identified membrane sites, that generate rapid non-genomic effects. We have recently identified a membrane androgen receptor site on prostate carcinoma cells, mediating testosterone rapid effects on the cytoskeleton and secretion within minutes. METHODS: The aim of this study was to investigate whether membrane androgen receptors are differentially expressed in prostate carcinomas, and their relationship to the tumor grade. We examined the expression of membrane androgen receptors in archival material of 109 prostate carcinomas and 103 benign prostate hyperplasias, using fluorescein-labeled BSA-coupled testosterone. RESULTS: We report that membrane androgen receptors are preferentially expressed in prostate carcinomas, and they correlate to their grade using the Gleason's microscopic grading score system. CONCLUSION: We conclude that membrane androgen receptors may represent an index of tumor aggressiveness and possibly specific targets for new therapeutic regimens

Results of endoscopic transsphenoidal pituitary surgery in 40 patients with a growth hormone-secreting macroadenoma

Contains fulltext : 96290.pdf (Publisher’s version ) (Open Access)OBJECTIVE: Transsphenoidal pituitary surgery (TS) is the primary treatment of choice for patients with acromegaly. Macroadenomas (>1 cm) are more difficult to resect than microadenomas (remission rate +/- 50% compared to +/- 90%). Besides the conventional microscopic TS, the more recently introduced endoscopic technique is nowadays frequently used. However, no large series reporting on its results have yet been published. We evaluated the outcome of endoscopic TS in 40 patients with a growth hormone (GH)-secreting macroadenoma treated in our hospital between 1998 and 2007. METHODS: Medical records were retrospectively reviewed. Remission was defined as disappearance of clinical symptoms of acromegaly, normal serum insulin-like growth factor-1 levels (</=2 SD) and serum GH levels suppressed to <2 mU/l after an oral glucose tolerance test within the first 4 months after TS. RESULTS: In four patients TS aimed at debulking of the tumour. In the remaining 36 patients, remission was achieved in 20 patients. In the first 5 years remission was achieved in 6 out of 18 patients (33%) compared to 14 out of 22 patients (63%) in the following 5 years (p = 0.06). Thirteen patients had a mild perioperative complication. Before TS 15 patients received hormonal substitution therapy compared to 12 patients (33%) after TS. CONCLUSION: Endoscopic TS is a good primary therapeutic option for patients with a GH-secreting macroadenoma, resulting in a remission rate of up to 63% in experienced hands. This technique can potentially improve the outcome of TS in these patients

Nicotinic Receptor Alpha7 Expression during Tooth Morphogenesis Reveals Functional Pleiotropy

The expression of nicotinic acetylcholine receptor (nAChR) subtype, alpha7, was investigated in the developing teeth of mice that were modified through homologous recombination to express a bi-cistronic IRES-driven tau-enhanced green fluorescent protein (GFP); alpha7GFP) or IRES-Cre (alpha7Cre). The expression of alpha7GFP was detected first in cells of the condensing mesenchyme at embryonic (E) day E13.5 where it intensifies through E14.5. This expression ends abruptly at E15.5, but was again observed in ameloblasts of incisors at E16.5 or molar ameloblasts by E17.5–E18.5. This expression remains detectable until molar enamel deposition is completed or throughout life as in the constantly erupting mouse incisors. The expression of alpha7GFP also identifies all stages of innervation of the tooth organ. Ablation of the alpha7-cell lineage using a conditional alpha7Cre×ROSA26-LoxP(diphtheria toxin A) strategy substantially reduced the mesenchyme and this corresponded with excessive epithelium overgrowth consistent with an instructive role by these cells during ectoderm patterning. However, alpha7knock-out (KO) mice exhibited normal tooth size and shape indicating that under normal conditions alpha7 expression is dispensable to this process. The function of ameloblasts in alpha7KO mice is altered relative to controls. High resolution micro-computed tomography analysis of adult mandibular incisors revealed enamel volume of the alpha7KO was significantly reduced and the organization of enamel rods was altered relative to controls. These results demonstrate distinct and varied spatiotemporal expression of alpha7 during tooth development, and they suggest that dysfunction of this receptor would have diverse impacts upon the adult organ

Futures trading, spot price volatility and market efficiency: evidence from European real estate securities futures

In 2007 futures contracts were introduced based upon the listed real estate market in Europe. Following their launch they have received increasing attention from property investors, however, few studies have considered the impact their introduction has had. This study considers two key elements. Firstly, a traditional Generalized Autoregressive Conditional Heteroskedasticity (GARCH) model, the approach of Bessembinder & Seguin (1992) and the Gray’s (1996) Markov-switching-GARCH model are used to examine the impact of futures trading on the European real estate securities market. The results show that futures trading did not destabilize the underlying listed market. Importantly, the results also reveal that the introduction of a futures market has improved the speed and quality of information flowing to the spot market. Secondly, we assess the hedging effectiveness of the contracts using two alternative strategies (naïve and Ordinary Least Squares models). The empirical results also show that the contracts are effective hedging instruments, leading to a reduction in risk of 64 %