69 research outputs found

    Liliana Zavaglia's White Apology and Apologia: Australian Novels of Reconciliation

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    Reading Kim Scott’s That Deadman Dance: Book Clubs and Postcolonial Literary Theory

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    This paper explores different readings of Kim Scott’s Miles Franklin award-winning novel That Deadman Dance, which offers a complex portrayal of cross-cultural contact on the so-called ‘Friendly Frontier’ of the southern coast of Western Australia in the early to mid-nineteenth century. This article contrasts academic responses to the novel with those of one of the most significant contemporary literary networks: book club readers. It draws upon Derek Attridge’s distinction between literal and allegorical readings, and Diana Fuss’s work on identification, to explore the extent to which different readers respond to the novel as an unfamiliar literary work in the context of literary sociability. I suggest that book club readings, in their tentative and open-ended uncertainty, pose a challenge to the orthodoxies of academic literary studies

    Narrating Historical Massacre: Alex Miller's Landscape of Farewell

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    This article scrutinises Alex Miller’s Landscape of Farewell (2007) through the lens of massacre. It explores the troubling implications of the novel’s sustained analogy between the generational effects for Indigenous Australian perpetrators of a massacre and the children of Nazis, and questions the novel’s capacity to contribute to reconciliation, in spite of drawing upon many of reconciliation’s key tropes. Drawing on the insights of comparative Holocaust studies, this article unpacks the novel’s representation of massacre and genocide, and the subtle comparison between Indigenous belonging to country and Nazi attachment to national space. Finally, through the work of Dominick LaCapra, it scrutinises the obfuscatory representation of the perpetrator, and the novel’s seeming projection of a form of perpetrator guilt onto the Indigenous subject

    Colonization rates of algae on artificial substrates in Douglas Lake.

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    General EcologyThe term 'algae' is applied to a diverse group of photosynthetic, autotrophic organisms. In the temperate kettle-lake Douglas Lake in Pellston, MI there are both planktonic and benthic taxa. The benthic organisms live on the lake floor or to fixed substrata using a variety of attachment techniques and generally follow a typical succession pattern from fast growing diatoms, to green algae and climaxing with the large, colonial blue-green algae. The study examined whether different types of surfaces may be more conducive to colonization and subsequent colony expansion. It also looked at the depth of submergence and the time submerged and their effect on the total algal coverage and the coverage by diatoms, green algae and blue-green algae individually. Results showed that concrete was more likely to support growth, though this was only significant for certain situations. There was no significant difference between depth submerged and only significant difference in time submerged at the deeper depth. There was a significant decrease in diatom coverage of concrete and a biologically significant increase in blue-green algae coverage on concrete over time. The growth of algae on artificial surfaces may have implications for the formation of microenvironments in lentic ecosystems and further study should focus on more diverse substrata and longer testing times.http://deepblue.lib.umich.edu/bitstream/2027.42/95919/1/Beaudry_Daher_Nolan_Petersen_2012.pd

    Precision gestational diabetes treatment: a systematic review and meta-analyses

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    Genotype-stratified treatment for monogenic insulin resistance: a systematic review

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    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

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    IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

    Sites of Benevolence

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    On the television show Backyard Blitz, Australians judged as deserving by their families and friends receive the gift of surprise makeovers to their gardens; in Australian public hospitals, trainee surgeons hone their skills on willing patients; in literary travel narratives, non-Indigenous Australian writers attempt to forge a relationship with the land and its traditional owners; and in inner-city Brisbane, the City Council builds lockers and sleeping areas for the park's homeless occupants. In Australian courts, legislators create copyright laws attempt to protect Indigenous ownership of traditional narratives; the South Australian Museum mounts a new Aboriginal Cultures Gallery; Indigenous actors face the challenges of racism as they practice their craft; and the Queensland government of the early twentieth century enacts policies of 'Aboriginal Protection'. At first, these instances seem to bear little meaningful relation to one another. However, as the articles in this special issue demonstrate, they all share a crucial common feature: all of these instances are moments or sites which are underpinned by benevolence. That is, each of these diverse instances is informed by one party's desire to 'do good' to another. Each involves the formation and negotiation of a specific kind of relationship between people or groups of people, a relationship driven by one party's desire to assist the other. This, then, is a special issue about good intentions, about gifts, and about the moral economies they articulate. As this issue reveals, benevolence is mobilised across a range of cultural sites and practices; the articles gathered in this issue explore the complexities of its diverse historical and contemporary manifestations
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