21 research outputs found
<Abstract of published report>Molecular analysis of extracellular-superoxide dismutase gene associated with high level in serum.
Get PDF<Abstract of Published Report>Polymorphism of Extracellular Superoxide Dismutase(EC-SOD) Gene : Relation to the Mutation Responsible for High EC-SOD Level in Serum.
Get PDFSelection of DNA aptamers using atomic force microscopy
Get PDFAtomic force microscopy (AFM) can detect the adhesion or affinity force between a sample surface and cantilever, dynamically. This feature is useful as a method for the selection of aptamers that bind to their targets with very high affinity. Therefore, we propose the Systematic Evolution of Ligands by an EXponential enrichment (SELEX) method using AFM to obtain aptamers that have a strong affinity for target molecules. In this study, thrombin was chosen as the target molecule, and an ‘AFM-SELEX’ cycle was performed. As a result, selected cycles were completed with only three rounds, and many of the obtained aptamers had a higher affinity to thrombin than the conventional thrombin aptamer. Moreover, one type of obtained aptamer had a high affinity to thrombin as well as the anti-thrombin antibody. AFM-SELEX is, therefore, considered to be an available method for the selection of DNA aptamers that have a high affinity for their target molecules
The Activities of Some Enzymes of Tryptophan Metabolism in Fetal, Neonatal and Adult Rat Liver and Kidney. I. Kynureninase and Kynurenine Aminotransferase
No full textIsozymes of rat brain AMP deaminase: Developmental changes and characterizations of five forms
No full textTissue distribution of GTP-binding protein, Go in rat and its postnatal development in brain
No full textThe non-indentity of yeast nicotinic acid mononucleotide pyrophosphorylase and nicotinic acid mononucleotidase
No full text<Abstract of published report>Molecular analysis of extracellular-superoxide dismutase gene associated with high level in serum.
No full text
<Abstract of Published Report>Polymorphism of Extracellular Superoxide Dismutase(EC-SOD) Gene : Relation to the Mutation Responsible for High EC-SOD Level in Serum.
No full text
