12,250 research outputs found
Analytic studies in the learning and memory of skilled performance second semi-annual report, oct. 1, 1964 - mar. 30, 1965
Analytic studies in learning and memory of skilled performanc
Feature Tracking Cardiac Magnetic Resonance via Deep Learning and Spline Optimization
Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an
area of interest for quantification of regional cardiac function from balanced,
steady state free precession (SSFP) cine sequences. However, currently
available techniques lack full automation, limiting reproducibility. We propose
a fully automated technique whereby a CMR image sequence is first segmented
with a deep, fully convolutional neural network (CNN) architecture, and
quadratic basis splines are fitted simultaneously across all cardiac frames
using least squares optimization. Experiments are performed using data from 42
patients with hypertrophic cardiomyopathy (HCM) and 21 healthy control
subjects. In terms of segmentation, we compared state-of-the-art CNN
frameworks, U-Net and dilated convolution architectures, with and without
temporal context, using cross validation with three folds. Performance relative
to expert manual segmentation was similar across all networks: pixel accuracy
was ~97%, intersection-over-union (IoU) across all classes was ~87%, and IoU
across foreground classes only was ~85%. Endocardial left ventricular
circumferential strain calculated from the proposed pipeline was significantly
different in control and disease subjects (-25.3% vs -29.1%, p = 0.006), in
agreement with the current clinical literature.Comment: Accepted to Functional Imaging and Modeling of the Heart (FIMH) 201
Beyond XSPEC: Towards Highly Configurable Analysis
We present a quantitative comparison between software features of the defacto
standard X-ray spectral analysis tool, XSPEC, and ISIS, the Interactive
Spectral Interpretation System. Our emphasis is on customized analysis, with
ISIS offered as a strong example of configurable software. While noting that
XSPEC has been of immense value to astronomers, and that its scientific core is
moderately extensible--most commonly via the inclusion of user contributed
"local models"--we identify a series of limitations with its use beyond
conventional spectral modeling. We argue that from the viewpoint of the
astronomical user, the XSPEC internal structure presents a Black Box Problem,
with many of its important features hidden from the top-level interface, thus
discouraging user customization. Drawing from examples in custom modeling,
numerical analysis, parallel computation, visualization, data management, and
automated code generation, we show how a numerically scriptable, modular, and
extensible analysis platform such as ISIS facilitates many forms of advanced
astrophysical inquiry.Comment: Accepted by PASP, for July 2008 (15 pages
A kinetic model of radiating electrons
A kinetic theory is developed to describe radiating electrons whose motion is governed by the Lorentz-Dirac equation. This gives rise to a generalized Vlasov equation coupled to an equation for the evolution of the physical submanifold of phase space. The pathological solutions of the 1-particle theory may be removed by expanding the latter equation in powers of τ ≔ q 2/6πm. The radiation-induced change in entropy is explored and its physical origin is discussed. As a simple demonstration of the theory, the radiative damping rate of longitudinal plasma waves is calculated
The view from elsewhere: perspectives on ALife Modeling
Many artificial life researchers stress the interdisciplinary character of the field. Against such a backdrop, this report reviews and discusses artificial life, as it is depicted in, and as it interfaces with, adjacent disciplines (in particular, philosophy, biology, and linguistics), and in the light of a specific historical example of interdisciplinary research (namely cybernetics) with which artificial life shares many features. This report grew out of a workshop held at the Sixth European Conference on Artificial Life in Prague and features individual contributions from the workshop's eight speakers, plus a section designed to reflect the debates that took place during the workshop's discussion sessions. The major theme that emerged during these sessions was the identity and status of artificial life as a scientific endeavor
Estimating Small Area Income Deprivation: An Iterative Proportional Fitting Approach
Small area estimation and in particular the estimation of small area income deprivation has
potential value in the development of new or alternative components of multiple deprivation
indices. These new approaches enable the development of income distribution threshold based
as opposed to benefit count based measures of income deprivation and so enable the
alignment of regional and national measures such as the Households Below Average Income
with small area measures. This paper briefly reviews a number of approaches to small area
estimation before describing in some detail an iterative proportional fitting based spatial
microsimulation approach. This approach is then applied to the estimation of small area HBAI
rates at the small area level in Wales in 2003-5. The paper discusses the results of this
approach, contrasts them with contemporary ‘official’ income deprivation measures for the
same areas and describes a range of ways to assess the robustness of the results
Universality and properties of neutron star type I critical collapses
We study the neutron star axisymmetric critical solution previously found in
the numerical studies of neutron star mergers. Using neutron star-like initial
data and performing similar merger simulations, we demonstrate that the
solution is indeed a semi-attractor on the threshold plane separating the basin
of a neutron star and the basin of a black hole in the solution space of the
Einstein equations. In order to explore the extent of the attraction basin of
the neutron star semiattractor, we construct initial data phase spaces for
these neutron star-like initial data. From these phase spaces, we also observe
several interesting dynamical scenarios where the merged object is supported
from prompt collapse. The properties of the critical index of the solution, in
particular, its dependence on conserved quantities, are then studied. From the
study, it is found that a family of neutron star semi-attractors exist that can
be classified by both their rest masses and ADM masses.Comment: 13 pages, 12 figures, 1 new reference adde
Global and regional left ventricular myocardial deformation measures by magnetic resonance feature tracking in healthy volunteers: comparison with tagging and relevance of gender
This work was funded by a grant from the Engineering and Physical Sciences Research Council (EP/G030693/1) and supported by the Oxford British Heart Foundation Centre of Research Excellence and the National Institute for Health Research Oxford Biomedical Research Centr
- …