Growing Up Amid Ethno‐Political Conflict: Aggression and Emotional Desensitization Promote Hostility to Ethnic Outgroups

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134287/1/cdev12599.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134287/2/cdev12599_am.pd

Topic Review Parents' Goals for Children: The Dynamic Coexistence of Individualism and Collectivism in Cultures and Individuals

Abstract Current scholarship on the cultural value systems of individualism and collectivism, and the associated developmental goals of autonomy and relatedness, has moved beyond grand divide theories to emphasize variation within individuals and cultures. We present a theoretical model on the dynamic coexistence of cultural value systems (at the macro level) and parents' developmental goals (at the micro leve

Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins

Cotranslational protein folding can facilitate rapid formation of functional structures. However, it might also cause premature assembly of protein complexes, if two interacting nascent chains are in close proximity. By analyzing known protein structures, we show that homomeric protein contacts are enriched towards the C-termini of polypeptide chains across diverse proteomes. We hypothesize that this is the result of evolutionary constraints for folding to occur prior to assembly. Using high-throughput imaging of protein homomers in vivo in E. coli and engineered protein constructs with N- and C-terminal oligomerization domains, we show that, indeed, proteins with C-terminal homomeric interface residues consistently assemble more efficiently than those with N-terminal interface residues. Using in vivo, in vitro and in silico experiments, we identify features that govern successful assembly of homomers, which have implications for protein design and expression optimization

Symbiodinium Transcriptomes: Genome Insights into the Dinoflagellate Symbionts of Reef-Building Corals

Dinoflagellates are unicellular algae that are ubiquitously abundant in aquatic environments. Species of the genus Symbiodinium form symbiotic relationships with reef-building corals and other marine invertebrates. Despite their ecologic importance, little is known about the genetics of dinoflagellates in general and Symbiodinium in particular. Here, we used 454 sequencing to generate transcriptome data from two Symbiodinium species from different clades (clade A and clade B). With more than 56,000 assembled sequences per species, these data represent the largest transcriptomic resource for dinoflagellates to date. Our results corroborate previous observations that dinoflagellates possess the complete nucleosome machinery. We found a complete set of core histones as well as several H3 variants and H2A.Z in one species. Furthermore, transcriptome analysis points toward a low number of transcription factors in Symbiodinium spp. that also differ in the distribution of DNA-binding domains relative to other eukaryotes. In particular the cold shock domain was predominant among transcription factors. Additionally, we found a high number of antioxidative genes in comparison to non-symbiotic but evolutionary related organisms. These findings might be of relevance in the context of the role that Symbiodinium spp. play as coral symbionts

The Friendships of Racial-Ethnic Minority Youth in Context

An extensive theoretical and empirical literature suggests that friendships are an important, if not essential, micro-context of adolescent development – shaping youth identity, school and civic engagement, and psychological and physical wellbeing. Friendships are also themselves embedded within, and shaped by, the larger macro-context of culture (Bronfenbrenner, 1979), including racial-ethnic stereotypes (García-Coll et al., 1996; Spencer, 1995). Yet, the study of friendship rarely examines the influence of the macro-context or includes racial-ethnic minority youth despite the fact that such youth represent half of the American youth population. In this chapter, we review research on the friendships of racial-ethnic minority youth and focus specifically on how the macro-context of social-identity based stereotypes shapes the micro-context of friendships