Improving eye–computer interaction interface design: Ergonomic investigations of the optimum target size and gaze-triggering dwell time

The Midas touch is reflected by the interactive feedback of interface functional elements, and a low level of spatial accuracy is related to the interaction area. This study tried to solve these two problems from the perspective of human-computer interactions and ergonomics. Two experiments were conducted to explore the optimum target size and gaze-triggering dwell time of the eye–computer interaction (ECI) system. Experimental Series 1 was used as the pre-experiment to identify the size that has a greater task completion rate. Experimental Series 2 was used as the main experiment to investigate the optimum gaze-triggering dwell time by using a comprehensive evaluation of the task completion rate, reaction time, and NASA-TLX (Task Load Index). In Experimental Series 1, the optimal element size was determined to be 256 × 256p x2. The conclusion of Experimental Series 2 was that when the dwell time is set to 600 ms, the efficiency of the interface is the highest, and the task load of subjects is minimal as well. Finally, the results of Experiment Series 1 and 2 have positive effects on improving the usability of the interface. The optimal control size and the optimal dwell time obtained from the experiments have certain reference and application value for interface design and software development of the ECI system

Production of proton-rich nuclei around Z=84-90 in fusion-evaporation reactions

Within the framework of the dinuclear system model, production cross sections of proton-rich nuclei with charged numbers of Z=84-90 are investigated systematically. Possible combinations with the $^{28}$Si, $^{32}$S, $^{40}$Ar bombarding the target nuclides $^{165}$Ho, $^{169}$Tm, $^{170-174}$Yb, $^{175,176}$Lu, $^{174,176-180}$Hf and $^{181}$Ta are analyzed thoroughly. The optimal excitation energies and evaporation channels are proposed to produce the proton-rich nuclei. The systems are feasible to be constructed in experiments. It is found that the neutron shell closure of N=126 is of importance during the evaporation of neutrons. The experimental excitation functions in the $^{40}$Ar induced reactions can be nicely reproduced. The charged particle evaporation is comparable with neutrons in cooling the excited proton-rich nuclei, in particular for the channels with $\alpha$ and proton evaporation. The production cross section increases with the mass asymmetry of colliding systems because of the decrease of the inner fusion barrier. The channels with pure neutron evaporation depend on the isotopic targets. But it is different for the channels with charged particles and more sensitive to the odd-even effect.Comment: 15 pages, 10 figures. arXiv admin note: text overlap with arXiv:0803.1117, arXiv:0707.258

Measurement uncertainty relation for three observables

In this work we establish rigorously a measurement uncertainty relation (MUR) for three unbiased qubit observables, which was previously shown to hold true under some presumptions. The triplet MUR states that the uncertainty, which is quantified by the total statistic distance between the target observables and the jointly implemented observables, is lower bounded by an incompatibility measure that reflects the joint measurement conditions. We derive a necessary and sufficient condition for the triplet MUR to be saturated and the corresponding optimal measurement. To facilitate experimental tests of MURs we propose a straightforward implementation of the optimal joint measurements. The exact values of incompatibility measure are analytically calculated for some symmetric triplets when the corresponding triplet MURs are not saturated. We anticipate that our work may enrich the understanding of quantum incompatibility in terms of MURs and inspire further applications in quantum information science. This work presents a complete theory relevant to a parallel work [Y.-L. Mao, et al., Testing Heisenberg's measurement uncertainty relation of three observables, arXiv:2211.09389] on experimental tests.Comment: arXiv admin note: substantial text overlap with arXiv:2211.0938

A Novel Uni-Acupoint Electroacupuncture Stimulation Method for Pain Relief

Electroacupuncture stimulation (EAS) has been demonstrated effective for pain relief and treating other various diseases. However, the conventional way of EAS, the bi-acupoint method, is not suitable for basis study of acupoint specificity. Moreover, its operations are inconvenient and difficult to be persevered, especially for long-term, continuous and even imperative treatments. These disadvantages motivate designs of new EAS methods. We present a novel uni-acupoint electrical stimulation method, which is applied at a single acupoint and quite meets the needs of basis study and simpler clinical application. Its pain relief effect has been evaluated by animal tests of Wistar rats. During the experiments, rats were given 30 min 2/100 Hz uni- and bi-acupoint EAS and their nociceptive thresholds before and after EAS were attained by hot-plate test. The analgesic effect was defined as the change of nociceptive threshold and used to evaluate the effectiveness of uni-acupoint EAS for pain relief. The hot-plate test results indicated that analgesic effect of uni-acupoint group was significantly higher than that of the control group and there was no significant difference of analgesic effects between uni- and bi-acupoint EAS. The results suggested that uni-acupoint method was an effective EAS method and had comparable pain relief effect with bi-acupoint method

Identification of subtype-specific metastasis-related genetic signatures in sarcoma

Background: Sarcomas are heterogeneous rare malignancies constituting approximately 1% of all solid cancers in adults and including more than 70 histological and molecular subtypes with different pathological and clinical development characteristics. Method: We identified prognostic biomarkers of sarcomas by integrating clinical information and RNA-seq data from TCGA and GEO databases. In addition, results obtained from cell cycle, cell migration, and invasion assays were used to assess the capacity for Tanespimycin to inhibit the proliferation and metastasis of sarcoma. Results: Sarcoma samples (N = 536) were divided into four pathological subtypes including DL (dedifferentiated liposarcoma), LMS (leiomyosarcoma), UPS (undifferentiated pleomorphic sarcomas), and MFS (myxofibrosarcoma). RNA-seq expression profile data from the TCGA dataset were used to analyze differentially expressed genes (DEGs) within metastatic and non-metastatic samples of these four sarcoma pathological subtypes with DEGs defined as metastatic-related signatures (MRS). Prognostic analysis of MRS identified a group of genes significantly associated with prognosis in three pathological subtypes: DL, LMS, and UPS. ISG15, NUP50, PTTG1, SERPINE1, and TSR1 were found to be more likely associated with adverse prognosis. We also identified Tanespimycin as a drug exerting inhibitory effects on metastatic LMS subtype and therefore can serve a potential treatment for this type of sarcoma. Conclusions: These results provide new insights into the pathogenesis, diagnosis, treatment, and prognosis of sarcomas and provide new directions for further study of sarcoma

Research and Application of Geotechnical Data Consistency in Marine Site Exploration

[Introduction] The current marine geological exploration, particularly the geotechnical investigation, often follows traditional experiences without a clear objective, and lacks the evaluations of soil sample disturbance and test results. Therefore, it is necessary to conduct in-depth research on marine geotechnical investigation technology. [Method] Based on the domestic and international research on marine geological exploration technology and multi-year working experience in different sea areas, we developed a new accurate marine geological exploration technology with emphasis on the principle of consistency. The geotechnical investigation part of the new method included two basic aspects: (1) comprehensive evaluation of soil sample disturbance; (2) comprehensive evaluation of consistency of soil strength test results. [Result] The three-dimensional cross-consistency analysis of geotechnical, geophysical, and geological models has established an accurate geological exploration system. Several examples of marine engineering projects showed that the new technology can screen good acquisition methods and data through comprehensive evaluation of clay soil sample disturbance, and conduct consistency analysis of various data by combining the laboratory geotechnical tests with in-situ tests and the routine geotechnical tests with advanced geotechnical tests to obtain richer and more continuous data at the borehole. Compared with the traditional single geotechnical test, our new technology demonstrated the improved reliability and accuracy of the data, and the missing data between the sampling points are compensated. [Conclusion] The proposed new method can reinforce the application of geological exploration data, reduce investigation costs, and provide more geotechnical parameters that are more reliable for marine engineering projects including offshore wind power

Research on the Engineering Geological Model and Its Application for Offshore Wind Power Development and Construction

[Introduction] Speeding up the offshore wind power construction and development is of great significance to promoting the adjustment of China's energy structure. China is accelerating the process of its wind power development in the entire offshore area, and the geological survey is a vital foundation and key technology of offshore wind power development. [Method] By studying the marine geological survey technologies at home and abroad and combining years of experience in different sea areas, this paper proposed a new technology of engineering geological modeling for offshore wind power development based on the principle of consistency. Firstly, the survey equipment selection and survey line layout started from a three-dimensional initial model to evaluate the impact of geological changes and geohazards on the offshore wind power engineering construction and took into full account the ship selection, field in situ and laboratory tests, and correlation of geophysical prospecting and geotechnical data. Then, with abundant and continuous data obtained from the boreholes and the whole wind farm during the feasibility study and detailed survey, the methods of combination of indoor geotechnical tests with the in-situ tests, the combination of multiple geophysical prospecting devices and the combination of geotechnical and geophysical prospecting methods were used to conduct a consistency analysis of various data, manage the geological survey data platform, update the model and build the final model, and the engineering geological model was continuously optimized and iterated in the subsequent stages. The engineering geological model provided comprehensive engineering geological information for the entire life cycle of offshore wind farm design, installation, operation, maintenance and decommissioning. [Result] The research results and offshore wind power geological survey examples show that by conducting consistent comprehensive layout and data analysis, effectively connecting geotechnical investigation with engineering geophysical prospecting and constructing a three-dimensional crossing engineering geological model, it can effectively solve the problem of "ambiguities of geological survey data" and improve the reliability, accuracy and application of geological survey data. [Conclusion] The new method proposed is one of the effective methods to reduce cost and increase efficiency in offshore engineering as well as the embryonic form of digital twin of offshore wind power geological survey and the foundation for the construction of a geological survey big data base

The Time Course of Age-related Emotional Preference in Task-irrelevant Affective Processing

Studies of the age-related positivity effect have demonstrated that older adults have a generalized preference to positive stimuli or avoidance to negative stimuli compared with younger adults. However, it remains unclear when and how this positive effect occurs in task-irrelevant affective processing in the aging brain. The present study investigated age-related emotional preference in one task-irrelevant affective stimuli processing by event-related brain potentials (ERPs) measurement with a specific focus on the time course of older adults' emotional processing and regulation. Younger and older adults completed a modified oddball task in which the deviant stimuli were affective faces. In the relatively early time window, the brain activities were not modulated by emotional valence in younger adults, yet the sad stimuli elicited a larger P3a than the happy and neutral ones in older adults. In the late time window, the sad stimuli elicited a larger positive slow wave than the happy stimuli in younger adults. Contrarily, at the later processing stage older adults' valence differences were eliminated. In general, we found time course differences in how older adults processed task-irrelevant affective stimuli compared, with the young, and an age-related positivity effect occurred in the late time window, manifested as a negativity preference in younger and no preferences in older adults. These results provided evidence for supporting socioemotional selectivity theory from an ERP approach