27 research outputs found

    CHALLENGES TO THE BRAZILIAN AGROFOOD INDUSTRY IN THE GLOBAL MARKET

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    A globalização da economia mundial vem sendo amplamente discutida, revolvendo um debate tanto teórico quanto ideológico a respeito dessa multifacetada transformação, com a qual todos os países vem se envolvendo. Independente dos rumos dessa discussão, a questão da competitividade tem se tornado essencial nas relações econômicas internacionais da última década, quando a maioria dos países começaram a promover uma abertura tanto aos fluxos de investimento quanto de comércio. Abstract Globalization has been deeply discussed revolving around a theoretical and ideological contention concerning this many-sided transformation with which, in one way or another, all countries have become entangled. Whatever the course of the discussion, competitiveness has become the key question in the international economic relations of the last decade, when most countries started opening up their economies to the external flows of trade and investment. The core of this analysis indicates the challenges facing Brazil in the international market when differentiated products appear to dominate trade relation. The discussion explores the extent to which foreign direct investment can change the conditions under which the country can boost its international competitiveness. As it will be argued here, the process of opening up the Brazilian economy in the 1990s has so far only consolidated the countrys position as a commodity exporter, whereas the mainstream of the international market has consisted of processed and differentiated products

    A agricultura nas negociações multilaterais da Rodada Doha e suas implicações para o Brasil

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    This article aims to analyse the evolution of world trade, with emphasis on the multilateral negotiations, since GATT was created in 1948, through the current Doha round of WTO. The role of institutions in building a favourable environment for free trade, particularly in agriculture, is stressed. After all, not only has the farming sector been crucial for the negotiations to succeed, but also for the trade relations of many developing countries, including Brazil. Besides, agriculture has been one of the most protected sectors in world trade and as such out of reach of GATT regulation until the conclusion of the Uruguay Round. Given that subsidies, tariffs and other mechanisms of protection still prevail in agricultural policies of some countries, this sector still remains as the deadlock of the unfinished Doha Round. That is why the previous expectations of progresses in trade liberalization have given place to a widespread uncertainty as the negotiations carry on.agricultural trade; Doha Round, Brazilian agriculture

    Molecular Characterization Of Intestinal Protozoa In Two Poor Communities In The State Of São Paulo, Brazil.

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    Several species of protozoa cause acute or chronic gastroenteritis in humans, worldwide. The burden of disease is particularly high among children living in developing areas of the world, where transmission is favored by lower hygienic standards and scarce availability of safe water. However, asymptomatic infection and polyparasitism are also commonly observed in poor settings. Here, we investigated the prevalence of intestinal protozoa in two small fishing villages, Porto Said (PS) and Santa Maria da Serra (SM), situated along the river Tietê in the State of São Paolo, Brazil. The villages lack basic public infrastructure and services, such as roads, public water supply, electricity and public health services. Multiple fecal samples were collected from 88 individuals in PS and from 38 individuals in SM, who were asymptomatic at the time of sampling and had no recent history of diarrheal disease. To gain insights into potential transmission routes, 49 dog fecal samples (38 from PS and 11 from SM) and 28 river water samples were also collected. All samples were tested by microscopy and PCR was used to genotype Giardia duodenalis, Blastocystis sp., Dientamoeba fragilis and Cryptosporidium spp. By molecular methods, the most common human parasite was Blastocystis sp. (prevalence, 45% in PS and 71% in SM), followed by D. fragilis (13.6% in PS, and 18.4% in SM) and G. duodenalis (18.2% in PS and 7.9% in SM); Cryptosporidium spp. were not detected. Sequence analysis revealed large genetic variation among Blastocystis samples, with subtypes (STs) 1 and 3 being predominant, and with the notable absence of ST4. Among G. duodenalis samples, assemblages A and B were detected in humans, whereas assemblages A, C and D were found in dogs. Finally, all D. fragilis samples from humans were genotype 1. A single dog was found infected with Cryptosporidium canis. River water samples were negative for the investigated parasites. This study showed a high carriage of intestinal parasites in asymptomatic individuals from two poor Brazilian villages, and highlighted a large genetic variability of Blastocystis spp. and G. duodenalis.810

    Molecular characterization of intestinal protozoa in two poor communities in the state of Sao Paulo, Brazil

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    Several species of protozoa cause acute or chronic gastroenteritis in humans, worldwide. The burden of disease is particularly high among children living in developing areas of the world, where transmission is favored by lower hygienic standards and scarce availability of safe water. However, asymptomatic infection and polyparasitism are also commonly observed in poor settings. Here, we investigated the prevalence of intestinal protozoa in two small fishing villages, Porto Said (PS) and Santa Maria da Serra (SM), situated along the river Tiete in the State of Sao Paolo, Brazil. The villages lack basic public infrastructure and services, such as roads, public water supply, electricity and public health services. Multiple fecal samples were collected from 88 individuals in PS and from 38 individuals in SM, who were asymptomatic at the time of sampling and had no recent history of diarrheal disease. To gain insights into potential transmission routes, 49 dog fecal samples (38 from PS and 11 from SM) and 28 river water samples were also collected. All samples were tested by microscopy and PCR was used to genotype Giardia duodenalis, Blastocystis sp., Dientamoeba fragilis and Cryptosporidium spp. By molecular methods, the most common human parasite was Blastocystis sp. (prevalence, 45% in PS and 71% in SM), followed by D. fragilis (13.6% in PS, and 18.4% in SM) and G. duodenalis (18.2% in PS and 7.9% in SM); Cryptosporidium spp. were not detected. Sequence analysis revealed large genetic variation among Blastocystis samples, with subtypes (STs) 1 and 3 being predominant, and with the notable absence of ST4. Among G. duodenalis samples, assemblages A and B were detected in humans, whereas assemblages A, C and D were found in dogs. Finally, all D. fragilis samples from humans were genotype 1. A single dog was found infected with Cryptosporidium canis. River water samples were negative for the investigated parasites. This study showed a high carriage of intestinal parasites in asymptomatic individuals from two poor Brazilian villages, and highlighted a large genetic variability of Blastocystis spp. and G. duodenalis8COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPsem informação2011/52100-

    MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals

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    Chromosomal translocations are characteristic of hematopoietic neoplasias and can lead to unregulated oncogene expression or the fusion of genes to yield novel functions. In recent years, different lymphoma/leukemia-associated rearrangements have been detected in healthy individuals. In this study, we used inverse PCR to screen peripheral lymphocytes from 100 healthy individuals for the presence of MLL (Mixed Lineage Leukemia) translocations. Forty-nine percent of the probands showed MLL rearrangements. Sequence analysis showed that these rearrangements were specific for MLL translocations that corresponded to t(4;11)(q21;q23) (66%) and t(9;11) (20%). However, RT-PCR failed to detect any expression of t(4;11)(q21;q23) in our population. We suggest that 11q23 rearrangements in peripheral lymphocytes from normal individuals may result from exposure to endogenous or exogenous DNA-damaging agents. In practical terms, the high susceptibility of the MLL gene to chemically-induced damage suggests that monitoring the aberrations associated with this gene in peripheral lymphocytes may be a sensitive assay for assessing genomic instability in individuals exposed to genotoxic stress
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