Balance Your Work-Life: Personal Interactive Web-Interface

The term work-life balance can be described as a path to manage stresses and burnouts in the workplace. In this Covid-19 pandemic, work-from-home practice includes both personal and professional spaces as employees, more often, stay digitally connected. As a result, personal life hardly can be separated, which will potentially create imbalanced life, which creates problems regarding physical and mental health of the employees. In such unprecedented situations, we are required to maintain and/or integrate balanced work-life. A balanced work-life gives employees a stress-free environment to work and improves employees' mental and physical health conditions and relationships. In this study, we focus on maintaining a proper work-life balance through a monitoring tool, the ‘Wheel of Life.’ Considering the drastic changes in work culture (due to Covid-19, for example), we introduce an interactive interface based on ‘Wheel of life’ concept. Our interface helps tune various important factors, such as business, creative, social, love and life purpose, and provides multiple recommendations. The purpose of the study is to assist web users to balance their work-life, improve psychological well-being and quality of life in this unforeseen situation

Wide-Area Power Oscillation Damping Control (POD) in Nordic Equivalent System

Abstract A study is presented on power oscillation damping control (POD) using wide area measurements applied to a single static var compensator (SVC). An equivalent power system model representing key characteristics of the Nordic power system is used. Feedback signals from remote phasor measurment units (PMUs) in Norway and Finland are used to damp the critical inter-area modes through a large SVC unit located in south-east Norway. A comparison between two control design approaches -(i) model based POD (MBPOD) -dependant on accurate system model and (ii) indirect adaptive POD (IAPOD) -which relies only on measurements -is made. For MBPOD an optimization approach is used to obtain the parameters of the controller while the IAPOD is based on online Kalman filter estimation and adaptive pole-shifting control. It is shown that the IAPOD yields almost similar performance as the MBPOD with very little prior information about the system. The performance comparison is verified for several tie-line outages

Stability Analysis of VSC MTDC Grids Connected to Multi-machine AC Systems

Abstract-Interaction between multi-machine AC systems and a multi-terminal DC (MTDC) grid and the impact on the overall stability of the combined AC-MTDC system is studied in this paper. A generic modeling framework for VSC-based MTDC grids which is compatible with standard multi-machine AC system models is developed to carry out modal analysis and transient simulation

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

Lipid profile abnormalities & 10 yr risk of CVD assessment among adult in North East India: A cross-sectional study

Background & objectives: In India, lifestyle changes have contributed to increase in the number of people suffering from lipid profile abnormalities, which is a major risk factor for coronary artery diseases. The present study was aimed to estimate the prevalence of lipid profile abnormalities and 10 yr risk of cardiovascular disease (CVD) among the adult population in west Tripura district and to study the association of lipid profile abnormalities and increased CVD risk with sociodemography, body mass index (BMI), hypertension, random blood sugar (RBS) and haemoglobin level. Methods: This cross-sectional study was conducted amongst 445 adults of 20 to 60 yr of age from a randomly selected block in west Tripura district. The 10 yr risk of CVD was estimated using the Framingham Risk Assessment Tool. Results: The study revealed that overall 83.4 per cent adult population had lipid profile abnormalities, with 22.2, 42 and 70.3 per cent of participants having hypercholesterolaemia, hypertriglyceridaemia and low high-density lipoprotein level, respectively. Gender (P=0.02) and BMI (P<0.001) were the significant determinants of dyslipidaemia. Only 3.8 per cent of participants had intermediate or high risk of CVD, with all of them being males. Gender, age, occupation and RBS were significantly associated with increased CVD risk. Interpretation & conclusions: The study revealed a high burden of lipid profile abnormalities in the study population, with males having more risk of CVD. Hence, periodic screening of lipid profile abnormalities and risk of CVD should be incorporated at the primary care level to combat the CVD epidemic in India

Multi-terminal direct-current grids: modeling, analysis, and control

A comprehensive modeling, analysis, and control design framework for multi-terminal direct current (MTDC) grids is presented together with their interaction with the surrounding AC networks and the impact on overall stability. The first book of its kind on the topic of multi-terminal DC (MTDC) grids  Presents a comprehensive modeling framework for MTDC grids which is compatible with the standard AC system modeling for stability studies Includes modal analysis and study of the interactions between the MTDC grid and the surrounding AC systems Addresses the problems of autonomous power sharing a

Wide-Area Phasor POD: A New Approach to Handling Time-Varying Signal Latency

Abstract Using present technology, latency associated with remote feedback signals can be determined from the time stamp information at both the PMU location and the control centre. This paper illustrates how this latency could be accounted for in the implementation of a widearea phasor power oscillation damping controller (phasor POD). The basic idea is to adjust the position of the rotating reference frame -used for phasor extraction -to account for the extra phase shift introduced due to latency. The oscillatory component of the original PMU measurement is retrieved out of the delayed signal received at the control centre. Thus, continuous compensation is achieved without requiring any Pade approximation and/or gain scheduling, unlike the techniques reported in the literature. With the proposed modification, a phasor POD is shown to continuously adapt to the actual latency and maintain the desired dynamic performance over a range of different operating conditions

The allylic nucleophilic substitution of Morita-Baylis-Hillman acetates with isocyanides: a facile synthesis of trisubstituted olefins

Morita-Baylis-Hillman acetates undergo smooth allylic nucleophilic substitution (SN2') with tosylmethyl isocyanide (TosMIC) in the presence of a catalytic amount of BF3·OEt2 under mild conditions to furnish trisubstituted olefins in high yields with (E)-stereoselectivity