New R Coronae Borealis and DY Persei Candidates in the SMC

We report 3 new R Coronae Borealis and 63 new DY Persei candidates in the Small Magellanic Cloud. Our analysis, based on data published by the OGLE team, consisted in a search for the characteristic drops in brightness that define these classes. All candidates had been previously classified as semi-regular or Mira variables. We briefly remark upon the possible existence of a ``borderline'' DY Per-like star and a ``transitional'' DY Per/RCB stars. Follow-up observations are needed to conclusively establish the nature of our candidates

New type II Cepheids from VVV data towards the Galactic center

The Galactic center (GC) is the densest region of the Milky Way. Variability surveys towards the GC potentially provide the largest number of variable stars per square degree within the Galaxy. However, high stellar density is also a drawback due to blending. Moreover, the GC is affected by extreme reddening, therefore near infrared observations are needed. We plan to detect new variable stars towards the GC, focusing on type II Cepheids (T2Cs) which have the advantage of being brighter than RR Lyrae stars. We perform parallel Lomb-Scargle and Generalized Lomb-Scargle periodogram analysis of the $K_s$-band time series of the VISTA variables in the Via Lactea survey, to detect periodicities. We employ statistical parameters to clean our sample. We take account of periods, light amplitudes, distances, and proper motions to provide a classification of the candidate variables. We detected 1,019 periodic variable stars, of which 164 are T2Cs, 210 are Miras and 3 are classical Cepheids. We also found the first anomalous Cepheid in this region. We compare their photometric properties with overlapping catalogs and discuss their properties on the color-magnitude and Bailey diagrams. We present the most extensive catalog of T2Cs in the GC region to date. Offsets in E($J-K_s$) and in the reddening law cause very large ($\sim$1-2 kpc) uncertainties on distances in this region. We provide a catalog which will be the starting point for future spectroscopic surveys in the innermost regions of the Galaxy.Comment: A&A, accepte

The VVV survey: Long-period variable stars I. Photometric catalog of ten VVV/OGLE tiles

Long-period variable stars (LPVs) are pulsating red giants, primarily in the asymptotic giant branch phase, and they include both Miras and semi-regular variables (SRVs). Their period-age and period-luminosity relations enable us to trace different stellar populations, as they are intrinsically very bright and cover a wide range in distances and ages. The purpose of this study is to establish a census of LPV stars in a region close to the Galactic center, using the six-year database of the Vista Variables in the V\'ia L\'actea (VVV) ESO Public Survey, as well as to describe the methodology that was employed to search for and characterize LPVs using VVV data. Near-IR surveys such as VVV provide a unique opportunity to probe the high-extinction innermost regions of the Milky Way. The detection and analysis of the intrinsically bright Miras in this region could provide us with an excellent probe of the properties of the Milky Way far behind its bulge. We used point-spread function photometry for all available $K_{s}$-band images in ten VVV tiles, covering $16.4~\deg^2$ in total, overlapping fields observed in the course of the Optical Gravitational Lensing Experiment (OGLE)-III survey. We designed a method to select LPV candidates, and we used the known variables from OGLE-III and other known variables from the literature to test our approach. The reduced $\chi^2$ statistic, along with the flux-independent index $K_{(fi)}$, were used in our analysis. The Lomb-Scargle period search method, Fourier analysis, template fitting, and visual inspection were then performed to refine our sample and characterize the properties of the stars included in our catalog. A final sample of 130 Mira candidates, of which 129 are new discoveries, was thus obtained, with periods in the range between about 80 and 1400~days

Large amplitude periodic outbursts and long period variables in the VVV VIRAC2-ββ database

© 2022 The Author(s) Published by Oxford University Press on behalf of the Royal Astronomical Society. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1093/mnras/stac768The VISTA Variables in the Via Lactea (VVV) survey obtained near-infrared photometry toward the Galactic bulge and the southern disc plane for a decade (2010 - 2019). We designed a modified Lomb-Scargle method to search for large-amplitude ($\Delta$Ks > 1.5 mag) mid to long-term periodic variables (P > 10 d) in the 2nd version of VVV Infrared Astrometric Catalogue (VIRAC2-$\beta$). In total, 1520 periodic sources were discovered, including 59 candidate periodic outbursting young stellar objects (YSOs), based on the unique morphology of the phase-folded light curves, proximity to Galactic HII regions and mid-infrared colours. Five sources are spectroscopically confirmed as accreting YSOs. Both fast-rise/slow-decay and slow-rise/fast-decay periodic outbursts were found, but fast-rise/slow-decay outbursts predominate at the highest amplitudes. The multi-wavelength colour variations are consistent with a variable mass accretion process, as opposed to variable extinction. The cycles are likely to be caused by dynamical perturbations from stellar or planetary companions within the circumstellar disc. An additional search for periodic variability amongst YSO candidates in published Spitzer-based catalogues yielded a further 71 candidate periodic accretors, mostly with lower amplitudes. These resemble cases of pulsed accretion but with unusually long periods and greater regularity. The majority of other long-period variables are pulsating dusty Miras with smooth and symmetric light curves. We find that some Miras have redder $W3 - W4$ colours than previously thought, most likely due to their surface chemical compositions.Peer reviewedFinal Accepted Versio

Exome sequencing utility in defining the genetic landscape of hearing loss and novel-gene discovery in Iran

Hearing loss (HL) is one of the most common sensory defects affecting more than 466 million individuals worldwide. It is clinically and genetically heterogeneous with over 120 genes causing non-syndromic HL identified to date. Here, we performed exome sequencing (ES) on a cohort of Iranian families with no disease-causing variants in known deafness-associated genes after screening with a targeted gene panel. We identified likely causal variants in 20 out of 71 families screened. Fifteen families segregated variants in known deafness-associated genes. Eight families segregated variants in novel candidate genes for HL: DBH, TOP3A, COX18, USP31, TCF19, SCP2, TENM1, and CARMIL1. In the three of these families, intrafamilial locus heterogeneity was observed with variants in both known and novel candidate genes. In aggregate, we were able to identify the underlying genetic cause of HL in nearly 30 of our study cohort using ES. This study corroborates the observation that high-throughput DNA sequencing in populations with high rates of consanguineous marriages represents a more appropriate strategy to elucidate the genetic etiology of heterogeneous conditions such as HL. © 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Lt

The VISTA Variables in the Vía Láctea eXtended (VVVX) ESO public survey: Completion of the observations and legacy

© 2024 ESO. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1051/0004-6361/202450584The ESO public survey VISTA Variables in the V\'ia L\'actea (VVV) surveyed the inner Galactic bulge and the adjacent southern Galactic disk from $2009-2015$. Upon its conclusion, the complementary VVV eXtended (VVVX) survey has expanded both the temporal as well as spatial coverage of the original VVV area, widening it from $562$ to $1700$ sq. deg., as well as providing additional epochs in $JHK_{\rm s}$ filters from $2016-2023$. With the completion of VVVX observations during the first semester of 2023, we present here the observing strategy, a description of data quality and access, and the legacy of VVVX. VVVX took $\sim 2000$ hours, covering about 4% of the sky in the bulge and southern disk. VVVX covered most of the gaps left between the VVV and the VISTA Hemisphere Survey (VHS) areas and extended the VVV time baseline in the obscured regions affected by high extinction and hence hidden from optical observations. VVVX provides a deep $JHK_{\rm s}$ catalogue of $\gtrsim 1.5\times10^9$ point sources, as well as a $K_{\rm s}$ band catalogue of $\sim 10^7$ variable sources. Within the existing VVV area, we produced a $5D$ map of the surveyed region by combining positions, distances, and proper motions of well-understood distance indicators such as red clump stars, RR Lyrae, and Cepheid variables. In March 2023 we successfully finished the VVVX survey observations that started in 2016, an accomplishment for ESO Paranal Observatory upon 4200 hours of observations for VVV+VVVX. The VVV+VVVX catalogues complement those from the Gaia mission at low Galactic latitudes and provide spectroscopic targets for the forthcoming ESO high-multiplex spectrographs MOONS and 4MOST.Peer reviewe

A Detailed Study of Leaf and Pollen Micromorphology of Some Species of Parietaria and Its Systematic Implication (Urticaceae)

Parietaria L. is a genus comprised of 20 species distributed throughout temperate and subtropical areas of the world. The leaf and pollen characters of four species of Parietaria from different locations in Iran were investigated with light and scanning electron microscopy, in order to assess their diagnostic significance to provide additional evidence on species delimitation. All pollen grains were small in size and found to be porate. Most of the pollen characters, such as shape and sculpturing of pollen grains, exine diameter, were overlapped between species and indicated limited taxonomic value. The pore and annulus diameter could be provided additional taxonomic characters that can be used for species delimitation in the genus. Moreover, the leaf epidermis provided new qualitative data (laminar hydathodes, bladder-based trichomes) that could delimit the species. The characters like twin stomata and laminar hydathode observed in P. officinalis were reported for the first time in this genus

Eur J Med Genet

Fragile X syndrome is the most common form of inherited mental retardation (MR). It is caused by the expansion of CGG triplet repeats in the fragile X mental retardation 1 (FMR1) gene. In mentally retarded males, the frequency of fragile X syndrome is approximately 2–3 percent, but little is known about its proportion in mentally retarded patients from countries where parental consanguinity is common. The objective of this study was to estimate the frequency of fragile X syndrome (FXS) in mentally retarded patients from Iran. We examined a total of 508 families with MR that had been referred to the Genetics Research Center (GRC) in Tehran of which 467 families had at least two mentally retarded children. In 384 families, the parents were related and in 124 they were not related of which most of them had putative or established X-linked inheritance pattern. Full FMR1 mutations were found in 32 of the 508 families studied (6.3%), in 19 out of 124 families with apparently unrelated parents (15.3%), and in 13 of the 384 consanguineous families (3.4%). Thus, in Iran, the relative frequency of FXS seems to be high, and in patients with unrelated parents is much higher. We also show that even in families with consanguineous parents, FXS has to be ruled out before assuming that familial MR is due to autosomal recessive gene defects. Molecular studies are in progress to explain the high proportion of FMR1 mutations in mentally retarded offspring of unrelated Iranian parents