SYSTEM-LEVEL HYBRID FAULT DIAGNOSABILITY WITH GENERAL TEST INVALIDATION

On the basis of a self-checking system model with general test invalidation the problem of diagnosability in the case of permanent and intermittent faults known as hybrid fault situation is discussed. Two hybrid fault models have been introduced that take into consideration the behaviour of the faulty tester. On the basis of the relationship that exists between the permanent and hybrid fault models, given the number of all units in a system, the upper bound of the number of diagnosable faulty units is defined without restriction on the test connection assignment

INFLUENCE OF ALUMINIUM ON T HE CONCENTRATION OF PHOSPHORUS AND ADENYL NUCLEOTIDES IN WHITE RAT ERYTHROCYTES

The experiment covered 126 white male rats divided into two groups: 70 poisoned rats (group one) and 56 control ones (group two). Animals from the first group were perorally introduced I per cent of water solution of AlCl3 in a dosis of 3 mg Al3+/kg body mass daily for 40 days. The concentrations of inorganic phosphorus and adenyl nucleotides such as AMP, ADP and ATP in rat erythrocytes were determined on the 5th, 10th, 15th, 20th, 30th, and 40th day of trial. An elevation of ATP concentration tending towards a shift to the left of ATP/ADP balance during the second half of the experiment was established. Inorganic phosphorus reduced significantly during the whole trial. These alterations testify to disturbed processes of erythrocytic energy Metabolism

BIOCHEMICAL PARAMETERS OF WORKERS EXPOSED TO MANGANESE

The study covered 34 workers from a manganese mine (group one) and 33 workers from a flux manufacture (group two). The following parameters were examined: total protein, protein fractions, immunoglobulins A, M, and G, total cholesterol, the enzyme activity of ASAT, ALAT, GLDH, LDH, and CE in the serum, as well as manganese in the blood by using the method of atomic absorption spectrophotometry. Blood manganese concentration was reliably elevated. There was reduction of total protein and albumin contents while alpha 2-globulins were enhanced for the second group only. The immunoglobulin A was increased which was more outlined for the group two whilst the total cholesterol increase was more manifested for the group one. All the enzymes were significantly activated. The necessity for dynamic follow-up of the parameters examined during the evaluation of the health risk and monitoring the health status of workers from manganese-dangerous projects was emphasized

EXPERIMENTAL INVESTIGATION OF THE EFFECT OF PERORALLY APPLIED ALUMINIUM ON THE STRUCTURE AND FUNCTION OF SOME INTERNAL ORGANS. LUNG ALTERATIONS IN RATS

The authors examined the lung lesions caused by peroral aluminium application as a 0,1 % solution of AlСl3 in a dose of 3 mg Al3+/kg b. w. for 40 days in a total of 126 white male rats (70 experimental and 56 control). Visible structural alterations were established on the 15th day of the trial consisting in desquamation of bronchial epithelium, enhanced pmounts of acid glucosaminoglycans in the cell cytoplasm and irregular disposition of cells. Later on, the activity of SDH, alkaline phosphatase, and ATP-ase decreased but acid phosphatase activity increased. Connective-tissue fibres grew up in the wall of some bronchi. These morphological findings suggest that although perorally accepted, AlСl3 induced structural lesions in the lungs as well as metabolic disturbances in the bronchial mucosa which depended on the duration of treatment

BIOLOGICAL PROPHYLAXIS OF OCCUPATIONAL EXPOSURE TO LEAD

No abstrac

MORPHOLOGICAL ALTERATIONS IN SPLEEN AND LYMPH NODES OF EXPERIMENTAL RATS TREATED WITH AICI3

No abstrac

Generalized quasi-Banach sequence spaces and measures of noncompactness

Given 0 &lt; s &#8804; 1 and &#968; an s-convex function, s &#8211; &#968; -sequence spaces are introduced. Several quasi-Banach sequence spaces are thus characterized as a particular case of s &#8211; &#968; -spaces. For these spaces, new measures of noncompactness are also defined, related to the Hausdorff measure of noncompactness. As an application, compact sets in s &#8211; &#968; -interpolation spaces of a quasi-Banach couple are studied.Dado 0 < s ? 1 e uma função s-convexa ?, os espaços de sequencias s – ? são introduzidos. Vários espaços quase-Banach de sequencias são assim caracterizados como um caso particular dos espaços s – ?. Para esses espaços novas medidas de não compacidade são também definidas, relacionadas a medida de não compacidade de Hausdorff. Como uma aplicação, conjuntos compactos nos espa, cos de interpolação s – ?, de um par quase-Banach são estudados.44345

Rare KIT (CD117) expression in multiple myeloma abrogates the usefulness of imatinib mesylate treatment

Background: Imatinib mesylate blocks the tyrosine kinase activity of KIT (CD117) and is an effective treatment for gastrointestinal stromal tumors. In multiple myeloma, KIT expression has been detected by flow cytometry in about 33% of specimens, but no previous immunohistochemical assessment has yet been made of the expression pattern of KIT. Materials and methods: We performed immunohistochemical analyses of 100 patients, including 72 with multiple myeloma (MM), 8 with lymphoplasmacytic lymphoma (LPL), 10 with monoclonal gammopathy of undetermined significance (MGUS) and 10 with reactive plasmocytosis. One KIT-positive MM was sequenced using polymerase chain reaction analysis. Results: In MM, only 2 cases (2.8%) were KIT positive. The great majority of the cases (97, 2%) did not express the KIT receptor tyrosine kinase. No mutation of the c-kit gene was detected. Conclusions: KIT expression is a rare event in MM and not detectable in MGUS and LPL. Therefore, treatment with imatinib is unlikely to be effective in these patient

Anesthetic considerations for microlaryngeal surgery

Introduction: Microlaryngeal surgery encompasses a wide range of laryngeal procedures. Patients presenting for microlaryngeal surgery frequently have a difficult airway. The chosen approach to this airway depends on the pathology and the patient’s symptoms. The Aim of the study is to determine the risk factors and anesthetic problems during microlaryngeal surgery.Materials and Methods: A prospective cohort study including 100 patients undergoing microlaryngeal surgery in the Department of Otorhinolaryngology at the University Hospital „Queen Giovanna“ – ISUL, Sofia, in the period 2020–2021; Medical University-Sofia. Preoperative examination of the larynx is performed in all patients by Storz 8402 ZX fiber optic laryngoscope with video capability.Results and discussion: In 69% of the patients the tumor mass causing obstruction is localized in the area of the larynx, and in 31% of them the tumor mass is localized in the area of the hypopharynx. From the patients with tumor mass causing laryngeal obstruction 42% are with 1st degree of obstruction, 29% are with 2nd degree, 27% are with 3rd degree and 2% are with respiratory failure at rest. Twenty six percent (26%) of the patients had pulse rate<45 beats per minute during putting on the tube of Kleinsasser. This is very dangerous reflex reaction of the heart, which we believe is caused by parasympathetic nervous system. The rate of difficult endotracheal intubation among patients presenting for microlaryngeal surgery is higher than among the general surgical patient population. Difficulties during endotracheal intubation in our study are due to higher percent of laryngeal obstruction and pharyngeal restriction because of the intraoral masses.Conclusion: Anesthesia for microlaryngeal surgery has always been demanding, as often pathology interferes with the anesthesiologist’s field of work

Synthesis and characterization of mixed oxides derivate from Li modified Mg-Al hydrotalcites

Lithium modified Mg/Al hydrotalcite-like samples with different Li content were synthesized using co-precipitation followed by calcination at 500 °C. The samples were characterized by means of XRD, DRIFTS, SEM-EDS, LDPSA and MIP. Results from this study indicated that the addition of Li modifier influences the change in structural, textural and morphological characteristics, more pronounced in samples with higher lithium content