Growth of a dry spot under a vapor bubble at high heat flux and high pressure

International audienceWe report a 2D modeling of the thermal diffusion-controlled growth of a vapor bubble attached to a heating surface during saturated boiling. The heat conduction problem is solved in a liquid that surrounds a bubble with a free boundary and in a semi-infinite solid heater by the boundary element method. At high system pressure the bubble is assumed to grow slowly, its shape being defined by the surface tension and the vapor recoil force, a force coming from the liquid evaporating into the bubble. It is shown that at some typical time the dry spot under the bubble begins to grow rapidly under the action of the vapor recoil. Such a bubble can eventually spread into a vapor film that can separate the liquid from the heater thus triggering the boiling crisis (critical heat flux)

RESEARCH OF NEUROPROTECTIVE ACTIVITY OF PHYTOREMEDY «PHYTOTON»

The research of neuroprotective activity of phytoremedy «Phytoton» was performed. In experiments on white rats (Wistarline) it was found that «Phytoton» possesses pronounced neuroprotective activity. «Phytoton» reduced. the level of anxiety in animals, attenuated substituting passive defensive reaction, increased orientation and exploratory behavior, and provided nootropic, anxiolytic, antihypoxia action

Problems of Subjective Imputability in Criminal Liability for Violating Rules Of Mining, Building Or Other Types Of Work

The article reveals the problem of implementing the principle of subjective imputability according to article 216 of the Criminal Code of the Russian Federation. It is stated that an objective basis prevails in enforcement of criminal liability for violation of rules when conducting mining, building and other types of work. Inevitability of such basis is explained by reasonability which in suchlike cases prevails over the idea of legality as an inevitable criterion of criminal law influence

Typical and Atypical Antipsychotic Drugs Increase Extracellular Histamine Levels in the Rat Medial Prefrontal Cortex: Contribution of Histamine H1 Receptor Blockade

Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics. In the present study, we examined the effects of antipsychotic drugs on histamine (HA) efflux in the mPFC of the rat by means of in vivo microdialysis and sought to differentiate the receptor mechanisms which underlie such effects. Olanzapine and clozapine increased mPFC HA efflux in a dose related manner. Increased HA efflux was also observed after quetiapine, chlorpromazine, and perphenazine treatment. We found no effect of the selective 5-HT2A antagonist MDL100907, 5-HT2c antagonist SB242084, or the 5-HT6 antagonist Ro 04-6790 on mPFC HA efflux. HA efflux was increased following treatment with selective H1 receptor antagonists pyrilamine, diphenhydramine, and triprolidine, the H3 receptor antagonist ciproxifan and the mixed 5-HT2A/H1 receptor antagonist ketanserin. The potential novel antipsychotic drug FMPD, which has a lower affinity at H1 receptors than olanzapine, did not affect HA efflux. Similarly, other antipsychotics with lower H1 receptor affinity (risperidone, aripiprazole, and haloperidol) were also without effect on HA efflux. Finally, HA efflux after antipsychotic treatment was significantly correlated with affinity at H1 receptors whereas nine other receptors, including 5-HT2A, were not. These results demonstrate that both typical and atypical antipsychotics increase mPFC histamine efflux and this effect may be mediated via antagonism of histamine H1 receptors

INFLUENCE OF PHYTOREMEDY «ANKSIOPHYT» EXTRACT ON DEVELOPMENT OF A CONDITIONED REFLEX IN WHITE RATS

Influence of phytoremedy of «Anksiophyt» extract on development of conditioned reflexes with a positive and. negative reinforcement was investigated. It is established that introduction to white rats (Wistar line) of «Anksiophyt» extract stimulates development of conditioned reflexes with a positive and. negative reinforcement at animals and causes safety of a memorable trace in the terms kept away after training

NOOTROPIC EFFECT OF COMPLEX PHYTOREMEDY «NOOPHYT» EXTRACT

In experiments on white rats (Wistar line) it was found that the dry extract of phytoremedy «Noophyt» pronounced nootropic effect. «Noophyt» extract in a volume of 0,2 and 0,5 ml/100 g simulated the development of conditioned reflexes of active and passive avoiding and caused to the saving of a memorable trace in the kept away terms after training оf intact animals and also in a volume of 0.5 ml/100g has a marked effect on the background antiamnesic skopolaminovoy amnesia

IN VITRO ANTIOXIDANT AND MEMBRANE STABILITY ACTIVITIES OF EXTRACTS FROM LOMATOGONIUM CARINTHIACUM (WULF.) REICHENB. AND HYPECOUM ERECTUM L

In the present study the antioxidant and membrane stability activities of Lomatogonium. carinthiacum. (Wulf.) Reichenb. and. Hypecoum. erectum. L. extracts was determined using in vitro methods. It was found that the remedies shown expressed antioxidant and. membrane stability activities as a result of inactivation of the reactive oxygen forms and. inhibition of lipids peroxidation process

Molecular Dynamics Simulation of Spinodal Decomposition in Three-Dimensional Binary Fluids

Using large-scale molecular dynamics simulations of a two-component Lennard-Jones model in three dimensions, we show that the late-time dynamics of spinodal decomposition in concentrated binary fluids reaches a viscous scaling regime with a growth exponent $n=1$, in agreement with experiments and a theoretical analysis for viscous growth.Comment: 4 pages, 3 figure