Spontaneous coronary artery dissection (scad)

Spontaneous coronary artery dissection is rare disease, occurring most often in young women. Clinical manifestation is acute coronary syndrome (ACS). Patogenetic of the disease is not known. Diagnosis is made by ECG, coronary angiography and optical coherence tomography. There are unclear recommendations concerning therapy. In patients with SCAD we recommend conservative therapy initially and then delayed PCI, optimally as OCT guided procedure. The use of biodegradable vascular scaffolds (BVS) could be the ideal option in treatment of atherosclerosis unaffected dissected coronary arteries

Laparoscopic Treatment Of High Sigmoidovaginal Fistula. Case Report

Rectovaginal and/or colovaginal fistulas are difficult-to-treat conditions that can cause vaginitis, abnormal flatulence through the vagina, skin excoriations, and more. Depending on the type of fistula, they can be rectovaginal, anovaginal, colovaginal, enterovaginal, vesicovaginal, ureterovaginal, urethrovaginal, with the most common being vesicovaginal and rectovaginal. In most cases, these conditions present a challenge and require a comprehensive diagnostic approach and treatment. We present a clinical case of a 73-year-old patient manifesting with flatulence through the vagina. During hospitalization, a high sigmoidovaginal fistula was diagnosed. The patient has a history of hysterectomy 17 years ago, due to myomatous uterus. Subsequently, she had three operations for postoperative hernia, two of which involved the placement of synthetic mesh. During the diagnostic plan, diverticulosis of the colon was also detected. This was observed as probable etiological cause for the formation of the fistula. The patient had comorbidities: arterial hypertension and severe obesity (Grade III). A laparoscopic disconnection of the fistula was performed, followed by laparoscopic suturing of the vagina and sigmoid colon, with subsequent omentoplasty. After an uncomplicated postoperative period, the patient was discharged on the 5th postoperative day, fully mobilized, with restored gas and feculent passage. There are few cases of high sigmoidoaginal fistulas described in the medical literature. The treatment in such patients is still unclear and subject to discussion. With the advancement of minimally invasive techniques in medicine, the laparoscopic surgical approach is a suitable option for treatment, but long-term follow-up and in-depth analyses are necessary

Late Diagnosis of Urinary Peritonitis Due to a Lesion of the Left Ureter During Laparoscopic Anterior Resection of the Rectum—Laparoscopic Solution. Clinical Case and Literature Review

Ureteral lesions are a rare complication of colorectal surgery. This type of surgical procedure is the second most common cause of such complications, second only to gynecological operations, which account for around 50%. According to the localization of the lesion, they аre grouped into three types: injury to the proximal, middle, and distal part of the ureter, with the latter being the most common—around 80–90%. Most of the lesions are not recognized intraoperatively and sometimes the diagnosis can be delayed significantly. The time of diagnosis and the localization of the injury are crucial to the choice of treatment. We present a case of a patient, with a late diagnosis of lesion of the left ureter after the laparoscopic anterior resection of the rectum, which was treated with a laparoscopic uretero-ureteral anastomosis with simultaneous double-J catheterization. We also present a short literature review on the subject

New Nanostructured Carbon Coating Inhibits Bacterial Growth, but Does Not Influence on Animal Cells

An electrospark technology has been developed for obtaining a colloidal solution containing nanosized amorphous carbon. The advantages of the technology are its low cost and high performance. The colloidal solution of nanosized carbon is highly stable. The coatings on its basis are nanostructured. They are characterized by high adhesion and hydrophobicity. It was found that the propagation of microorganisms on nanosized carbon coatings is significantly hindered. At the same time, eukaryotic animal cells grow and develop on nanosized carbon coatings, as well as on the nitinol medical alloy. The use of a colloidal solution as available, cheap and non-toxic nanomaterial for the creation of antibacterial coatings to prevent biofilm formation seems to be very promising for modern medicine, pharmaceutical and food industries

New imaging methods of coronary arteries

Coronary angiography is still the most widely used method for assessment of lumen of coronary arteries and for diagnostics and treatment of coronary artery disease. New imaging modalities of coronary arteries play increasing role in interventional cardiology. Intravascular ultrasound (IVUS) is the oldest technology. Due to high tissue penetration it is very important for imaging of left main coronary artery and saphenous vein grafts. IVUS was used in many clinical trials and clinical experience with it is huge. Optical coherence tomography (OCT) is a new, very fast developing method. It has ten times higher axial resolution than IVUS. It gives us the opportunity to assess the inner structures of coronary artery wall, to evaluate the characteristics of atherosclerotic plaques, quality of stent implantation and its healing. It helps us to find the culprit lesion of acute coronary syndrome in some cases, to diagnose the cause of stent thrombosis, to evaluate stent apposition which has a direct relation to prognosis. We use it for performing of complex percutaneous coronary interventions and after heart transplantation to diagnose the vascular graft disease. We strongly believe that OCT is important for assessment of plaque instability and patient´s prognosis. Near infrared spectroscopy combined with IVUS can distinguish fibrous from lipid core plaques. Lipid core burden index is in relation to a risk of periprocedural myocardial infarction and to prognosis. It is the only method which can sufficiently detect the amount of lipids in coronary wall

An Optical Microscope Study of the Morphology of Xenon Hydrate Crystals: Exploring New Approaches to Cryopreservation

One of the possible approaches to a new method of cryopreservation seems to be the controlled formation of a multitude of small crystals in an object, which, due to their size, will not damage cellular structures. Managing the crystal formation, given the stochastic nature of the process, is an extremely difficult task. Theoretically, it is simplified if there is a sufficient number of changeable physical parameters, affecting the process. From this point of view, the use of ice-like gas hydrates for the purposes of cryopreservation seems to be a promising option. We investigated the process of growth of xenon gas hydrates via standard microscopy under different conditions using the specialized optical cell for observation at elevated pressures. The formation of crystals was observed in the system “supercooled liquid–xenon–water vapor„ at negative, near-zero and positive values of temperature, and pressure of xenon up to 8 atmospheres. The morphology of xenon hydrate crystals observed in the experiments was analyzed and classified into five categories. The influence of physical conditions on the predominant crystal morphology was also studied. We found no evidence that the possible damaging effect of hydrate crystals should be less severe than of ice crystals

EFFECT OF OXYGEN CONTENT ON THE NON-ISOTHERMAL OXIDATION OF WASTE SLAG FROM COPPER PRODUCTION

Oxidation of waste slag from copper production was studied in oxygen-nitrogen gaseous mixtures (21, 43, 63 and 100 vol.% of O2) under non-isothermal conditions using DTA-TG analysis at constant gas flow rate of 30 ml min-1 and varying heating rate. The results revealed that the mechanism of slag oxidation does not change with changing the oxygen content but intensification of the process occurs. Kinetic analysis was performed and a decrease in the values of the activation energy was observed with increasing of the oxygen partial pressure