Pengaruh Karakteristik Perusahaan terhadap Pengungkapan Tanggung Jawab Sosial dengan Kepemilikan Institusional sebagai Variabel Moderasi

The research aims to analyze the influence of corporate characteristic on the disclosure of corporate social responsibility with institutional ownership as a moderating variable. The population of this research is manufacture companies listed in Indonesia Stock Exchange (IDK) 2011-2015. Research sampling used purposive sampling technique. There are 22 samples that meet the criteria as a sample of research with 5 years of observation. The total sample studied was 110. The multiple regression analysis was used for hypothesis testing. The results indicate that firm size, firm age, and leverage have a significant influence on the corporate social responsibility; and simultaneously firm size, firm age, and leverage have a significant influence on the corporate social responsibility. Meanwhile, institutional ownership weakens the effect of firm size on the disclosure of social responsibility. While institutional ownership weakens the effect of firm age and leverage on the disclosure of social responsibility. Keywords: Corporate Social Responsibility Disclosure, Firm Size, Firm Age, Leverage, Institutional ownershi

STRATEGI PENGELOLAAN SANITASI DALAM UPAYA MENDUKUNG DESA WISATA DI DESA SERUNI MUMBUL LOMBOK TIMUR

 Kebutuhan akan ketenangan akan suatu obyek wisata membuat seseorang sering memilih lokasi obyek wisata yang memenuhi kebutuhan kenyamanannya. Desa Seruni merupakan tempat wisata buatan yang baru dibangun tahun 2019. Di tempat ini pengunjung bisa menikmati pesona rawa-rawa, dan memiliki puluhan mata air. Kondisi lingkungan di Desa Seruni Mumbul maupun di obyek wisata masih banyak terdapat kekurangan dalam pengelolaan sanitasinya, demikian juga pasilitas, sumber daya, alokasi anggaran yang belum memadai. Toilet yang tersedia masih belum memenuhi kebutuhan wisatawan, pengelolaan sampah belum ditangani dengan baik, pasilitas penangannan sampah juga masih kurang. Adapun sasaran yang ingin dicapai adalah untuk mengkaji sistem sanitasi yang diterapkan pada objek wisata Desa Seruni Mumbul. Metode yang digunakan adalah deskriptif kualitatif dengan teknik survey, wawancara  serta  dokumentasi.  Berdasarkan hasil analisis data dan pembahasan diperoleh bahwa sistem sanitasi pada objek wisata  belum memenuhi standar sanitasi yang ditentukan oleh Kementerian Kesehatan RI. Terdapat beberapa tempat yang telah memperhatikan standar kebersihan, dan telah memenuhi standar sanitasi minimaldi beberpa tempat. Sistem sanitasi yang diterapkan antara lain meliputi sanitasi dasar, penyediaan air bersih, Pembuangan air limbah, ketersediaan tempat sampah, jarak toilet serta penerangan. Sedangkan di beberpa tempat belum sepenuhnya memenuhi kriteria Sanitasi

Hubungan antara Masa Kerja dengan Kadar Timbal (Pb) dalam Darah pada Pekerja Industri Pengecoran Logam CV. Bonjor Jaya di Desa Batur, Ceper, Klaten

Lead is a toxic substance that has cumulative effect and harmful to human health. Metal foundry is a metal industry that has the potential contributes pollutants lead into the air. So that workers in the foundry including people at risk of exposure metallic lead, because the raw materials used metal may contain lead. Purpose of this research is to determine the relationship between working period and lead concentration in blood at the metal foundry industry workers CV. BonjorJaya in Batur, Ceper, Klaten. The research method used analytical observation with cross sectional design. Total of samples are 31 people with purposive sampling. Analysis of data, the writer used Chi Square test with a significance level of 0,05 and 95% confidence level. The results were obtained concentration Pb in the air parts of the foundry are 0,208 mg/Nm3, printing are 0,212 mg/Nm3 and finishing are 0,037 mg/Nm3. Mean lead concentration in blood of the workers was 14,38 µg/dL with minimum concentration of 3,00 µg/dL, maximum of 37,40 µg/dL. Mean working period was 10,11 years with the most recent of working period one year and the longest 28 years. As many as 51,6% of workers had Pb concentration in blood above normal (>10 µg/dL). Based on the results of statistical tests showed that there was no relationship between working period and lead concentration in blood at the metal foundry industry workers CV. Jaya Bonjor in Batur, Ceper, Klaten (p value = 1,000). Suggestion for the company, monitoring work environment about air quality especially lead and held a medical checks for workers in periodic, establish policy about limitation of working period and job site and use of Personal Protective Equipment. For workers suggested obligatory use of PPE and pay attention personal hygiene in the workplace

Studi Prevalensi Keracunan Pestisida Pada Petani Penyemprot Sayur Di Desa Mendongan Kecamatan Sumowono Kabupaten Semarang

Mendongan village is one of the producers of vegetables in the use of pesticides are still high, of which 100% of the farmers in the village Mendongan use pesticides to kill pests. Results of preliminary studies, 75% of farmers do not use full protective equipment when spraying vegetables. In Semarang District also has been no monitoring of pesticide poisoning by the District Health Office and there has been no thorough assistance of puskesmas officers related to the use of pesticides by farmers. The purpose of this study was to determine the prevalence of pesticide poisoning in spraying vegetable farmers in the village Mendongan Sumowono District of Semarang District. The research location is in the village Mendongan Sumowono District of Semarang District. This study was observational analytic with cross sectional study design. Samples of this study were 38 respondents. Data analysis using Chi Square. The results showed a 44.7% level of knowledge is not good, the frequency of spraying 5.3% often, completeness APD 31.6% of respondents did not complete, 97.4% of respondents working lives long, long hose down 26.3%> 3 hours a day, spraying 2.6% one time, the dose of pesticides used 28.9% of respondents do not match, the wind direction while spraying 5.3% in the opposite direction, and the amount of pesticides 31.6%> 3 types. Cholinesterase level examination results showed 100% of respondents are still in a state of normal. The result of the relationship of nine independent variables studied there is no meaningful relationship to lower levels of cholinesterase in the blood of farmers, but based on the value of RP (Prevalence Ratio) when spraying (PR = 1.768; 95% CI = 1.330 to 2.334) and wind direction (PR = 1.800; 95% CI = 1.344 to 2.411) are risk factors for low levels of cholinesterase. The conclusion from this study that the prevalence of poisoning in spraying vegetable farmer in the village Mendongan Sumowono District of Semarang District of 0

Effects of Lifestyle Measures, Antiobesity Agents, and Bariatric Surgery on Serological Markers of Inflammation in Obese Patients

Overweight and obesity are highly prevalent in developed countries and are also becoming more frequent in the developing world. Overweight and obese patients have elevated levels of several inflammatory markers and this inflammatory state might contribute to their increased vascular risk. We summarize the effects of lifestyle changes, antiobesity agents, and bariatric surgery on serological inflammatory markers in overweight and obese patients. Most studies showed a decrease in inflammation with all 3 interventions. However, it remains to be established whether the decrease in inflammatory markers induced by lifestyle changes or (where indicated) with antiobesity agents or bariatric surgery will translate into reduced vascular morbidity and mortality in overweight and obese patients

18 alpha-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures

Aims: Proteasomes are constituents of the cellular proteolytic networks that maintain protein homeostasis through regulated proteolysis of normal and abnormal (in any way) proteins. Genetically mediated proteasome activation in multicellular organisms has been shown to promote longevity and to exert protein antiaggregation activity. In this study, we investigate whether compound-mediated proteasome activation is feasible in a multicellular organism and we dissect the effects of such approach in aging and Alzheimer's disease (AD) progression. Results: Feeding of wild-type Caenorhabditis elegans with 18 alpha-glycyrrhetinic acid (18 alpha-GA; a previously shown proteasome activator in cell culture) results in enhanced levels of proteasome activities that lead to a skinhead-1- and proteasomeactivation-dependent life span extension. The elevated proteasome function confers lower paralysis rates in various AD nematode models accompanied by decreased A beta deposits, thus ultimately decelerating the progression of AD phenotype. More importantly, similar positive results are also delivered when human and murine cells of nervous origin are subjected to 18 alpha-GA treatment. Innovation: This is the first report of the use of 18 alpha-GA, a diet-derived compound as prolongevity and antiaggregation factor in the context of a multicellular organism. Conclusion: Our results suggest that proteasome activation with downstream positive outcomes on aging and AD, an aggregation-related disease, is feasible in a nongenetic manipulation manner in a multicellular organism. Moreover, they unveil the need for identification of antiaging and antiamyloidogenic compounds among the nutrients found in our normal diet.Peer reviewe

Asociando la imagen con el mito en monedas cretenses antiguas: Tres casos de estudio

Cretan coinage is characterized by a multitude of iconographic types, very often mythological in content. Various mythical figures and episodes are often difficult to identify or interpret due to either lack of clues that would lead to an interpretation or to the fact that could be identifiable with more than one existing myth. Thus, the identification of imagery on Cretan coins is not always self evident. Three major mints of the island are examined in this paper in order to investigate local myths, compared with the mythological tradition of mainland Greece; the myth of the Tree Nymph of Gortyn, the myth of the Labyrinth of Knossos and the myth of the Dog-nursed Infant of Kydonia. Cretan cities, through coin imagery and by carefully selecting the represented mythical figures, were bonding their citizens with a certain heritage, offering a sense of belonging, continuation and ethnic pride, differentiating themselves from other ethnic groups and city states of the island.La acuñación de moneda cretense se caracteriza por una multitud de tipos iconográficos, muy a menudo de contenido mitológico.Varias figuras y episodiosmíticos suelenser difíciles de identificar o interpretar debido a la falta de indicios que conduzcan a una interpretación o al hecho de que podrían identificarse con más de un mito existente. Por lo tanto, la identificación de la imaginería en las monedas cretenses no siempre es evidente. En este artículo se examinan las tres casas de la moneda principales de la isla para investigar los mitos locales, en comparación con la tradición mitológica de la Grecia continental; el mito de la ninfa del árbol de Gortina, el mito del laberinto de Cnosos y el mito del niño de Cidonia amamantado por una perra. Las ciudades cretenses, a través de la imaginería de las monedas y seleccionando cuidadosamente las figuras míticas representadas, vinculaban a sus ciudadanos con un cierto legado cultural, ofreciendo un sentido de pertenencia, continuación y orgullo étnico, diferenciándose a sí mismas de otros grupos étnicos y ciudades estado de la isla

Smoking status in relation to serum folate and dietary vitamin intake

Objective Cigarette smoke itself is an abundant source of free radicals and a major cause of oxidative stress, to which plasma antioxidants function as a vital protective and counterbalancing mechanism. The objective of this study was to investigate into the relationship between smoking status and serum and dietary micronutrient concentrations. Design Cross-sectional study Subjects ' Setting 502 farmers from the Valley of Messara in Crete were randomly selected and examined. Complete three-day and 24-hr recall questionnaires were collected along with anthropometrical, physical activity and clinical data from all participating subjects. Results After adjusting for age, gender and number of fasting days adhered to per year, current smokers were found to have a lower dietary intake of vitamin C (112.1 mg vs. 136.4 mg, p = 0.03), fibre (16.6 g vs. 19.1 g, p = 0.006) and fruits and vegetables (339 g vs. 412 g, p = 0.014), while dietary vitamin B1 intake was found to be higher (1.7 mg vs. 1.4 mg, p = 0.02) in comparison to non/ex smokers. Dietary intake of meat, folate and vitami A, E, B2, B6 and B12 did not differ between the groups. Controlling age, gender, fasting days and dietary micronutrient intake, serum folate levels were found to be lower among smokers (geometric mean 15.3 nmol/L vs. 17.7 nmol/L, p = 0.023), while serum iron and vitamin B12 levels were not affected by smoking status. Conclusion Current smoking status affects dietary nutrient intake as well as plasma folate levels. The above coherence between antioxidant depletion and reduced antioxidant intake may predispose smokers to the premature development of tobacco related mortality and morbidity