100 research outputs found

    Effect of intracellular free calcium mobilization on aggregation of umbilical cord blood platelets.

    Get PDF
    &#60;P&#62;Aggregation activity of platelets in umbilical blood is lower than that in adult blood, but the reason for this is not well understood. It has recently been clarified that calcium plays a role as a second messenger of platelet aggregation, and that glycoproteins of platelet surface membrane such as glycoprotein I b and IIb/IIIa are receptors for agonists inducing aggregation. We examined the concentrations of intracellular calcium and the membrane glycoproteins of platelets in umbilical and adult blood. The increase of intracellular calcium in umbilical platelets was lower than that in adult platelets when the aggregation was induced by ADP, collagen, thrombin and epinephrine. Only calcium ionophore A23187 induced aggregation of both umbilical and adult platelets. On the other hand, there were no qualitative differences between glycoproteins I b and IIb/IIIa of these two groups. Therefore, the low aggregation activity of umbilical platelets seems to be due to low responsiveness of the intracellular calcium system, not to the disorder of functional surface membrane glycoprotein.&#60;/P&#62;</p

    Measurements of μμ pairs from open heavy flavor and Drell-Yan in p+p collisions at √s=200  GeV

    Get PDF
    PHENIX reports differential cross sections of μμ pairs from semileptonic heavy-flavor decays and the Drell-Yan production mechanism measured in p+p collisions at √s=200  GeV at forward and backward rapidity (1.2<|η|<2.2). The μμ pairs from c¯c, b¯b, and Drell-Yan are separated using a template fit to unlike- and like-sign muon pair spectra in mass and pT. The azimuthal opening angle correlation between the muons from c¯c and b¯b decays and the pair-pT distributions are compared to distributions generated using pythia and powheg models, which both include next-to-leading order processes. The measured distributions for pairs from c¯c are consistent with pythia calculations. The c¯c data present narrower azimuthal correlations and softer pT distributions compared to distributions generated from powheg. The b¯b data are well described by both models. The extrapolated total cross section for bottom production is 3.75±0.24(stat)±0.350.50(syst)±0.45(global)  [μb], which is consistent with previous measurements at the Relativistic Heavy Ion Collider in the same system at the same collision energy and is approximately a factor of 2 higher than the central value calculated with theoretical models. The measured Drell-Yan cross section is in good agreement with next-to-leading-order quantum-chromodynamics calculations

    Nonperturbative-transverse-momentum broadening in dihadron angular correlations in √sNN=200GeV proton-nucleus collisions

    Get PDF
    The PHENIX collaboration has measured high-pT dihadron correlations in p+p, p+Al, and p+Au collisions at √sNN=200 GeV. The correlations arise from inter- and intrajet correlations and thus have sensitivity to nonperturbative effects in both the initial and final states. The distributions of pout, the transverse-momentum component of the associated hadron perpendicular to the trigger hadron, are sensitive to initial- and final-state transverse momenta. These distributions are measured multidifferentially as a function of xE, the longitudinal momentum fraction of the associated hadron with respect to the trigger hadron. The near-side pout widths, sensitive to fragmentation transverse momentum, show no significant broadening between p+Au, p+Al, and p+p. The away-side nonperturbative pout widths are found to be broadened in p+Au when compared to p+p; however, there is no significant broadening in p+Al compared to p+p collisions. The data also suggest that the away-side pout broadening is a function of Ncoll, the number of binary nucleon-nucleon collisions, in the interaction. The potential implications of these results with regard to initial- and final-state transverse-momentum broadening and energy loss of partons in a nucleus, among other nuclear effects, are discussed

    Measurement of charm and bottom production from semileptonic hadron decays in p+p collisions at √s=200  GeV

    Get PDF
    Measurements of the differential production of electrons from open-heavy-flavor hadrons with charm- and bottom-quark content in p+p collisions at √s=200  GeV are presented. The measurements proceed through displaced-vertex analyses of electron tracks from the semileptonic decay of charm and bottom hadrons using the PHENIX silicon-vertex detector. The relative contribution of electrons from bottom decays to inclusive heavy-flavor-electron production is found to be consistent with fixed-order-plus-next-to-leading-log perturbative-QCD calculations within experimental and theoretical uncertainties. These new measurements in p+p collisions provide a precision baseline for comparable forthcoming measurements in A+A collisions
    corecore