The Educational Needs of the Patients who Take Treatment in Psychiatric Clinic in Kars

AbstractThis study was done with the aim of to determine the educational needs of the patients who take treatment in psychiatric clinic in Kars. The study which is a cross-sectional was made in Kars Government Hospital's Psychiatric Clinic with 50 patients, between 02.01.2012 - 30.04.2012. In collecting data, a questionnaire and the Educational Needs Questionnaire (EDQ) were used. The participants who takes place in the survey, the patients includes who have depression diagnosis are (40%) and men (66%). When we look to the points mean average that they get from the EDQ is 29.04 ± 5.59. According to the EDQ: the 3 articles which they get the highest marks in order are: “Anger, violence, assaultive behaviour”, “Sleeping problems”, “Problems with concentration” and “Patients self-help organizations”. Educational Needs, it was seen that; the ones who has nuclear family, who has social guarantee, who applies to non-medical people, who has social supporters from their family, who lose their job because of mental illness, who has a belief that they will be get well, have a higher point of mean average. According to these results, it is supposed that the educational programs must be planned due to the fact that the patients have needs for information and when doing this the needs of the patients must be remembered

Evaluation of Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios in Rheumatoid Arthritis

Objective: The purpose of this study is to investigate the relationship of disease activity with Neutrophil-Lympho­cyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) and red blood cell distribution width (RDW). Methods: Seventy seven RA patients and 97 healthy sub­jects were examined retrospectively. People with chronic and systemic diseases were excluded from control group of the study. The disease activity scores (DAS 28) of pa­tient group, hematologic parameters and inflammation parameters of both groups were analyzed statistically us­ing independent t-test and spearman correlation test. Results: Age and gender was not found different be­tween groups. CRP and ESR levels were significantly higher in RA group (p<0.001). Hemoglobin and platelet count were lower (p<0.001 and p=0.022), while RDW, NLR, PLR and MPV levels were significantly higher in RA group (p<0.001, p<0.001. p<0.001, p<0.001, respec­tively). In patient group, ESR (p<0.001), lymphocytes (%) (p= 0.042), absolute neutrophil (p=0.047), and platelets (p= 0.019) were positively, whereas lymphocytes were negatively affected by improvement disease activity (DAS 28) scores. PLR levels significantly negatively correlated with MPV levels (r= -0.386) but showed a significant posi­tive correlation with RDW (r= 0.354) and NLR levels (r= 0.618). Conclusion: NLR and PLR are important and promising factors for disease activity estimation of rheumatoid ar­thritis and may be used in clinical practice. In our opinion, larger studies consisting larger group will help determina­tion of disease activity of RA by more specific indices us­ing these parameters

Analysis of intestinal and nasopharyngeal microbiota of children with meningococcemia in pediatric intensive care unit: INMACS-PICU study

This article belongs to the Special Issue Pediatric Diagnostic Microbiology.Microbiota composition might play a role in the pathophysiology and course of sepsis, and understanding its dynamics is of clinical interest. Invasive meningococcal disease (IMD) is an important cause of community-acquired serious infection, and there is no information regarding microbiota composition in children with meningococcemia. In this study, we aimed to evaluate the intestinal and nasopharyngeal microbiota composition of children with IMD.[Materials and Methods]: In this prospective, multi-center study, 10 children with meningococcemia and 10 age-matched healthy controls were included. Nasopharyngeal and fecal samples were obtained at admission to the intensive care unit and on the tenth day of their hospital stay. The V3 and V4 regions of the 16S rRNA gene were amplified following the 16S Metagenomic Sequencing Library Preparation.[Results]: Regarding the alpha diversity on the day of admission and on the tenth day at the PICU, the Shannon index was significantly lower in the IMD group compared to the control group (p = 0.002 at admission and p = 0.001, on the tenth day of PICU). A statistical difference in the stool samples was found between the IMD group at Day 0 vs. the controls in the results of the Bray–Curtis and Jaccard analyses (p = 0.005 and p = 0.001, respectively). There were differences in the intestinal microbiota composition between the children with IMD at admission and Day 10 and the healthy controls. Regarding the nasopharyngeal microbiota analysis, in the children with IMD at admission, at the genus level, Neisseria was significantly more abundant compared to the healthy children (p < 0.001). In the children with IMD at Day 10, genera Moraxella and Neisseria were decreased compared to the healthy children. In the children with IMD on Day 0, for paired samples, Moraxella, Neisseria, and Haemophilus were significantly more abundant compared to the children with IMD at Day 10. In the children with IMD at Day 10, the Moraxella and Neisseria genera were decreased, and 20 different genera were more abundant compared to Day 0.[Conclusions]: We first found alterations in the intestinal and nasopharyngeal microbiota composition in the children with IMD. The infection itself or the other care interventions also caused changes to the microbiota composition during the follow-up period. Understanding the interaction of microbiota with pathogens, e.g., N. meningitidis, could give us the opportunity to understand the disease’s dynamics.This study was supported by the Eskisehir Osmangazi University Scientific Research Grant (2018/11046).Peer reviewe

Some Characterizations Of Generalized Null Mannheim Curves In Semi-Euclidean Space

WOS:000539253800001In the present paper, we investigate Cartan framed generalized null Mannheim curves in the four-dimensional semi-Euclidean space of index two. We construct the Cartan (or Frenet) frames and curvature functions of generalized Mannheim mate curve with the help of curvatures and Cartan frames of generalized null Mannheim curve

On generalized null Mannheim curves in E24

WOS:000521599600001In the present paper, we introduce the notion of Cartan-framed generalized null Mannheim curves in four-dimensional semi-Euclidean space with index 2, E24. We obtain the Cartan (or Frenet) frames and curvature functions of the generalized Mannheim mate curve by the help of curvature functions and Cartan frames of the generalized null Mannheim curve. We proved that there are no generalized null Mannheim curves with timelike principal normal N in E24. The related examples and their projected images are also given

On generalized null Mannheim curves in E24

WOS: 000521599600001In the present paper, we introduce the notion of Cartan-framed generalized null Mannheim curves in four-dimensional semi-Euclidean space with index 2, E24. We obtain the Cartan (or Frenet) frames and curvature functions of the generalized Mannheim mate curve by the help of curvature functions and Cartan frames of the generalized null Mannheim curve. We proved that there are no generalized null Mannheim curves with timelike principal normal N in E24. The related examples and their projected images are also given

Osculating curves in 4-dimensional semi-Euclidean space with index 2

WOS: 000404573600001In this paper, we give the necessary and sufficient conditions for non-null curves with non-null normals in 4-dimensional Semi-Euclidian space with indeks 2 to be osculating curves. Also we give some examples of non-null osculating curves in E-2(4)

Activity and bioaccessibility of antioxidants in yoghurt enriched with black mulberry as affected by fermentation and stage of fruit addition

Pasteurised whole milk was acidified with bacterial culture or glucono-delta-lactone (GDL) to determine effects of fermentation and pH reduction on activity and in vitro bioaccessibility of antioxidants and physical properties of yoghurt with black mulberry. Both pH reduction and fermentation were found to influence activity and bioaccessibility of antioxidants in mulberry yoghurt. Total phenolic content of the sample prepared with bacterial culture was higher than that of the sample with GDL, while there was a similar level of reduction in both samples after three weeks of storage at 4 degrees C. Fermentation with the bacterial culture yielded lower copper reducing activity but higher DPPH scavenging activity compared with acidification with GDL. Bioaccessibility of the antioxidants in in vitro gastrointestinal system was less than 25% in all samples. Addition of fruit after acidification or fermentation of milk, rather than before, resulted in higher antioxidant activity, higher consistency coefficient and less serum separation. (C) 2021 Elsevier Ltd. All rights reserved.WOS:0006349608000052-s2.0-8510132003