Is Bit It?

In his famous “It from Bit” essay, John Wheeler contends that the stuff of the physical universe (“it”) arises from information (“bits” – encoded yes or no answers). Wheeler’s question and assumptions are re-examined from a post Aspect experiment perspective. Information is examined and discussed in terms of classical information and “quanglement” (nonlocal state sharing). An argument is made that the universe may arise from (or together with) quanglement but not via classical yes/no information coding

A simple operational interpretation of the fidelity

This note presents a corollary to Uhlmann's theorem which provides a simple operational interpretation for the fidelity of mixed states.Comment: 1 pag

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia

Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Design and setting: Analysis of prospectively collected data from the National Coronial Information System on deaths where codeine toxicity was determined to be an underlying or contributory cause of death. The study period was 2000–2013. Main outcome measures: Population-adjusted numbers (per million persons) of (1) codeine-related deaths, classified by intent (accidental or intentional); and (2) heroin- and Schedule 8 opioid-related deaths (as a comparator). Results: The overall rate of codeine-related deaths increased from 3.5 per million in 2000 to 8.7 per million in 2009. Deaths attributed to accidental overdoses were more common (48.8%) than intentional deaths (34.7%), and their proportion increased during the study period. High rates of prior comorbid mental health (53.6%), substance use (36.1%) and chronic pain (35.8%) problems were recorded for these deaths. For every two Schedule 8 opioid-related deaths in 2009, there was one codeine-related death. Most codeine-related deaths (83.7%) were the result of multiple drug toxicity. Conclusions: Codeine-related deaths (with and without other drug toxicity) are increasing as the consumption of codeine-based products increases. Educational messages are needed to better inform the public about the potential harms of chronic codeine use, especially in the context of polypharmacy

'The difficulties of communication encountered by Indigenous peoples’: moving beyond Indigenous deficit in the model admission rules for legal practitioners

The Law Admissions Consultative Committee’s Model Admission Rules 2015 require new practising lawyers to have an ‘awareness’ of the difficulties of communication attributable to cultural differences, including ‘the difficulties of communication encountered by Indigenous peoples’ (LACC: 31). While there is no doubt that effective cross-communication is essential to providing ethical legal representation for clients from diverse cultural backgrounds, this paper will argue that in the context of the First Peoples of Australia greater regulatory attention to these issues is urgently needed and that the ‘difficulties of communication’ need to be framed differently. Numerous reports and inquiries have shown that First Peoples’ encounters with the Australian legal system are fraught with a lack of cultural understanding on the part of non-Indigenous legal actors. Given the ongoing and systemic over-representation of First Peoples in the criminal justice system and child protection regimes, there is a critical need for lawyers to develop Indigenous cultural competency as one step towards addressing this gross injustice, and making the Australian legal system more responsive to the needs and aspirations of First Peoples. Canadian developments, particularly in the wake of the final report of the Truth and Reconciliation Commission, underline the scale and significance of this need, and provide some broader context for a reconsideration of legal education and professional admission requirements in Australia. This paper will argue that Indigenous cultural competency should be a mandatory requirement for admission to legal practice in Australia, and that the ‘deficit discourse’ on First Peoples’ engagement with the legal system must be discarded, to ensure that legal ethical and professional responsibilities are inclusive of the needs of First Peoples

Meta-Analysis of Cyathostomin Species-Specific Prevalence and Relative Abundance in Domestic Horses from 1975-2020: Emphasis on Geographical Region and Specimen Collection Method

BACKGROUND: Cyathostomins infect virtually all horses, and concomitant infections with 10 or more species per horse is standard. Species-specific knowledge is limited, despite potential species bias in development of disease and anthelmintic resistance. This is the first meta-analysis to examine effects of geographical region and cyathostomin collection method on reported composition of cyathostomin communities. METHODS: Thirty-seven articles published in English in 1975 or later, in which adults of individual species were systematically enumerated, were included. Seven regions; North America, South America, eastern Europe, western Europe, northern Europe, southern Africa, and Oceania, and three cyathostomin collection methods; (i) standard necropsy recovery from the large intestine, (ii) critical test collection from post-treatment feces and necropsy, and (iii) diagnostic deworming recovery solely from post-treatment feces, were considered. Generalized mixed linear models analyzed the effects of region and collection method on species-specific prevalence and relative abundance. Species richness was analyzed by mixed linear models. RESULTS: Definitively, the most prevalent and relatively abundant species were Cylicocyclus nassatus (prevalence = 93%, relative abundance = 20%), Cylicostephanus (Cys.) longibursatus (93%, 20%), and Cyathostomum catinatum (90%, 16%). A bias toward horses with high infection intensities and cyathostomin collection from feces resulted in North American critical tests and eastern European diagnostic deworming overestimating the species-specific prevalence and underestimating the relative abundance of rare/uncommon species compared to respective intra-regional standard necropsies. North American critical tests underestimated species richness due partially to identification key errors. Inter-regional standard necropsy comparisons yielded some species-specific regional differences, including a significantly higher Cys. longibursatus prevalence and relative abundance in North America (92%, 33%) than in eastern Europe (51%, 7%) (P \u3e 0.0001). Localization of critical tests to North America and diagnostic deworming to Eastern Europe precluded expansive ‘region by collection method’ interaction analyses. CONCLUSION: We provide substantial data to inform study design, e.g. effect and study size, for cyathostomin research and highlight necessity for method standardization and raw data accessibility for optimal post-factum comparisons

A mechanism-focused approach to the science of behavior change: An introduction to the special issue

The National Institutes of Health (NIH) Science Of Behavior Change initiative (SOBC; https://commonfund.nih.gov/behaviorchange)—supported by the NIH Common Fund (https://commonfund.nih.gov/)—is an explicit effort to address the stymied and siloed behavior change field. As described in this Special Issue, SOBC represents a fundamental change in the way that research on initiation, personalization, and maintenance of behavior change is being conducted and applied. In this editorial, we highlight key contributions of SOBC in these areas