Chinese Strategic Asset Seeking Activity in the United States

With the continual economic growth of China, the importance of Chinese foreign direct investment and where this investment is directed grows as well. There has been research within the last decade looking into the significance of strategic-asset-seeking (SAS) when determining the factors of Chinese foreign direct investment (FDI). SAS is classified as foreign direct investment that targets technology, patents, stocks, and human capital. Numerous studies have found differing results when measuring the significance of SAS in determining FDI. This literature review compares completed research in order to find how the measurement of SAS affects location models. For this review data of Chinese FDI in the US is used to test the significance of SAS in developed nations

Oral History Interview: Paul Niday

This interview is one of a series conducted with former employees of the Huntington Owens-Illinois, Inc. glass bottle factory. Mr. Paul Niday, born October 16, 1933, began working at Owens- Illinois, Inc. in 1952. He performed numberous jobs at the plant and retired in 1993 as a mechanical foreman, just seven months before the plant shutdown. Mr. Niday discusses the details of his work, changes that occurred over the years, union activities, company-sponsored events and the specific contributions of blacks and women at the factory.https://mds.marshall.edu/oral_history/1422/thumbnail.jp

Infusing EL Content and Instruction into English Education Courses

An article presenting a five-stage process of infusing EL-relevant topics into English education courses

Do Ten Year Trends in Emergency Department Diagnoses of Rhabdomyolysis in Young Adult Males Parallel the Growth in Long Distance Ultra Running?

Ultra running, a sport that consists of races above the marathon marker of 26.2 miles, has rarely been studied in depth. Little peer-reviewed scientific information examines the morbidity or disease prevalence associated with long-distance ultrarunning. Furthermore, there is an increase in reports of rhabdomyolysis within the ultrarunning community, which may coincide with an increase in the demand for long-distance ultrarunning races. This study examined the rate of hospital or emergency room admissions with a diagnosis of rhabdomyolysis and assesses if the incidence of rhabdomyolysis events in young males parallels the growth of ultrarunning. We hypothesized that: • ED diagnoses of rhabdomyolysis in young adult males parallel the growth in ultrarunning. • There are geographic and seasonal variations in the population rate of ER, which correspond to locations and times where most training for ultrarunning events occurs. A regression test to trend the races & rhabdomyolysis frequencies/rates over time was conducted using patient data from NIS database and racing data from Ultrarunning.com. Our research has demonstrated a rise in the rates of rhabdomyolysis that mirror the rise of long-distance ultra running in young adult males

Seismic anisotropy reveals crustal flow driven by mantle vertical loading in the Pacific NW

Buoyancy anomalies within Earth’s mantle create large convective currents that are thought to control the evolution of the lithosphere. While tectonic plate motions provide evidence for this relation, the mechanism by which mantle processes influence near-surface tectonics remains elusive. Here, we present an azimuthal anisotropy model for the Pacific Northwest crust that strongly correlates with high-velocity structures in the underlying mantle but shows no association with the regional mantle flow field. We suggest that the crustal anisotropy is decoupled from horizontal basal tractions and, instead, created by upper mantle vertical loading, which generates pressure gradients that drive channelized flow in the mid-lower crust. We then demonstrate the interplay between mantle heterogeneities and lithosphere dynamics by predicting the viscous crustal flow that is driven by local buoyancy sources within the upper mantle. Our findings reveal how mantle vertical load distribution can actively control crustal deformation on a scale of several hundred kilometers

Seismic anisotropy reveals crustal flow driven by mantle vertical loading in the Pacific NW

Buoyancy anomalies within Earth’s mantle create large convective currents that are thought to control the evolution of the lithosphere. While tectonic plate motions provide evidence for this relation, the mechanism by which mantle processes influence near-surface tectonics remains elusive. Here, we present an azimuthal anisotropy model for the Pacific Northwest crust that strongly correlates with high-velocity structures in the underlying mantle but shows no association with the regional mantle flow field. We suggest that the crustal anisotropy is decoupled from horizontal basal tractions and, instead, created by upper mantle vertical loading, which generates pressure gradients that drive channelized flow in the mid-lower crust. We then demonstrate the interplay between mantle heterogeneities and lithosphere dynamics by predicting the viscous crustal flow that is driven by local buoyancy sources within the upper mantle. Our findings reveal how mantle vertical load distribution can actively control crustal deformation on a scale of several hundred kilometers

Epilepsy-associated KCNQ2 channels regulate multiple intrinsic properties of layer 2/3 pyramidal neurons

© 2017 the authors. KCNQ2 potassium channels are critical for normal brain function, as both loss-of-function and gain-of-function KCNQ2 variants can lead to various forms of neonatal epilepsy. Despite recent progress, the full spectrum of consequences as a result of KCNQ2 dysfunction in neocortical pyramidal neurons is still unknown. Here, we report that conditional ablation of Kcnq2 from mouse neocortex leads to hyperexcitability of layer 2/3 (L2/3) pyramidal neurons, exhibiting an increased input resistance and action potential frequency, as well as a reduced medium after hyperpolarization (mAHP), a conductance partly mediated by KCNQ2 channels. Importantly, we show that introducing the KCNQ2 loss-of-function variant KCNQ2I205V into L2/3 pyramidal neurons using in utero electroporation also results in a hyperexcitable phenotype similar to the conditional knock-out. KCNQ2I205V has a right-shifted conductance-to-voltage relationship, suggesting loss of KCNQ2 channel activity at subthreshold membrane potentials is sufficient to drive large changes in L2/3 pyramidal neuronal excitability even in the presence of an intact mAHP. We also found that the changes in excitability following Kcnq2 ablation are accompanied by alterations at action potential properties, including action potential amplitude in Kcnq2-null neurons. Importantly, partial inhibition of Nav1.6 channels was sufficient to counteract the hyperexcitability of Kcnq2-null neurons. Therefore, our work shows that loss of KCNQ2 channels alters the intrinsic neuronal excitability and action potential properties of L2/3 pyramidal neurons, and identifies Nav1.6 as a new potential molecular target to reduce excitability in patients with KCNQ2 encephalopathy

TASTEX gamma spectrometer system for measuring isotopic and total plutonium concentrations in solutions

Described is a computer-based gamma ray spectrometer system using a germanium detector for rapid nondestructive measurement of isotopic and total plutonium concentrations in solutions at nuclear reprocessing plants. Isotopic concentrations have been measured with an accuracy of +-0.5%. Cell design, calibration techniques, and preliminary results are discussed. This system is being installed at the Tokai reprocessing plant in Japan