Alien Registration- Nicola, Ruggieri (Bangor, Penobscot County)

https://digitalmaine.com/alien_docs/9817/thumbnail.jp

Columen, cantherii, transtra et capreoli: intorno alla genesi delle incavallature lignee

The herein paper proposes a diachronic analysis of the timber carpentry roof in the roman context. It is based on cross attestations deriving from ancient literary sources, the iconography emphasized in artefacts belonging to different figurative arts that reproduce timber structures and on the beam sockets still present in some constructions. The analysed roof carpentries developed in antiquity in Greece, Magna Graece and Etruria, were , in general, constituted by a horizontal member on which struts rest,  with the role of supporting two oblique members that form the roof pitch. An organization that persisted in the roman constructive culture at least until the 4th century when the truss system, able to generate new interrelations among the component elements, became particularly widespread

Carpenteria di legno dei tetti e dei solai interpiano a pompei nel I secolo D.C.

The timber elements of the Pompeii’s buildings were subjected to high temperatures during the 79 A.D. Vesuvius’ eruption that entailed the almost total loss of the roofs and inter-floors carpentry heritage. However, wooden structures evidences are still present. In fact, many wooden members pockets and frescos representing realistic architectural scenes, compared with the Latin sources, provide precious data for determining floors and roofs structural organization in Pompeii during the 1st century A.D. The carpentry configurations, put in evidence in the herein study, are classifiable in several typologies, in dependence of the covered span and the use of the supported room. They vary from floors characterized by one order of beams on which a wooden boarding bears to more complex organizations that include structures identifiable as king post trusses or ante-litteram lattice trusses

Long-term radiographic and clinical-functional outcomes of isolated, displaced, closed talar neck and body fractures treated by ORIF: the timing of surgical management

Background: The main purpose of this retrospective case series study was to evaluate long-term radiographic and clinical outcomes of a consecutive series of patients diagnosed with isolated, displaced, closed talar neck or body fractures treated by open reduction and internal fixation (ORIF). Secondly, the aim was to verify the influence of the location of talar fractures on the outcomes, the prognostic value of the Hawkins sign, whether operative delays promote avascular necrosis (AVN) and if the fractures require emergent surgical management. Methods: From January 2007 to December 2012, at our institution, 31 patients underwent ORIF through the use of screws. On the basis of Inokuchi criteria, the injuries were divided between neck and body fractures, which were classified according to Hawkins and Sneppen, respectively. The patients included were divided into two groups in relation to fracture location and complexity. Radiographic assessment focused on reduction quality, bone healing, the Hawkins sign and post-traumatic arthritis (PTA) development. For the clinical evaluation, clinical-functional scores (AOFAS Ankle-Hindfoot Score; MFS; FFI-17; SF-36) and VAS were determined, and statistical analysis was performed. Results: 27 patients, 19 males and 8 females, mean age 38.3 years, were included with an average follow-up period of 83.2 months (range 49\u2013119). There were 9 neck and 19 body fractures; their reduction was anatomical or nearly anatomical in 22 cases, and all reached radiographic consolidation after a mean period of 3.4 months (range 1.7\u20137). The Hawkins sign was observed in 9 cases, in which necrosis did not develop. With a 0\u201311 day surgical timing interval, more than 60% of the patients obtained good or fair results with different scores, while 18 (66.7%) were completely satisfied (VAS: 9\u201310). The early complications included malunions (21.4%) and wound problems (25%); the late complications involved AVN (25%) and PTA (78.6%). Conclusions: Despite a high rate of long-term complications, satisfactory clinical results were achieved. Talar fracture location did not influence the outcomes, the Hawkins sign was confirmed as a positive prognostic factor, and operation timing did not influence AVN development. Hence, these injuries do not require emergent surgical management by ORIF

I terremoti del I secolo d.C. a Pompei. Osservazioni intorno ai danni e consolidamenti nelle Terme Stabiane con particolare riguardo ad uno sperone nel Destrictarium

The 62 AD represents for Pompeii the beginning of a sequence of telluric events culminating with the complete town burial provoked by the Vesuvius’ eruption. The traces of those earthquakes, some of which of high magnitude able to produce damage to the constructions, are still detectable on the ancient structures.The paper analyzes some significant masonry walls of the Terme Stabiane emphasizing cracks and deformations due to two distinct earthquakes, by evaluating the reconstruction, repair and strengthening interventions carried out during the roman age.Furthermore, a constructive analysis, conducted on the buttress present in the destrictarium and regarding the materials and their organization, with the aid of the Mechanics, have provided information on the chronology of the events occurred, in sequence, during the 1st century AD

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients

Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation. We studied the homeostasis of the cholinergic system in relation to cytokine levels in immune cells and sera of relapsing remitting-MS (RR-MS) patients. We demonstrated that lower ACh levels in serum of RR-MS patients were inversely correlated with the increased activity of the hydrolyzing enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). Interestingly, the expression of the ACh biosynthetic enzyme and the protein carriers involved in non-vesicular ACh release were found overexpressed in peripheral blood mononuclear cells of MS patients. The inflammatory state of the MS patients was confirmed by increased levels of TNF alpha, IL-12/IL-23p40, IL-18. The lower circulating ACh levels in sera of MS patients are dependent on the higher activity of cholinergic hydrolyzing enzymes. The smaller ratio of ACh to TNF alpha, IL-12/IL-23p40 and IL-18 in MS patients, with respect to healthy donors (HD), is indicative of an inflammatory environment probably related to the alteration of cholinergic system homeostasis