Network design decisions in supply chain planning

Structuring global supply chain networks is a complex decision-making process. The typical inputs to such a process consist of a set of customer zones to serve, a set of products to be manufactured and distributed, demand projections for the different customer zones, and information about future conditions, costs (e.g. for production and transportation) and resources (e.g. capacities, available raw materials). Given the above inputs, companies have to decide where to locate new service facilities (e.g. plants, warehouses), how to allocate procurement and production activities to the variousmanufacturing facilities, and how to manage the transportation of products through the supply chain network in order to satisfy customer demands. We propose a mathematical modelling framework capturing many practical aspects of network design problems simultaneously. For problems of reasonable size we report on computational experience with standard mathematical programming software. The discussion is extended with other decisions required by many real-life applications in strategic supply chain planning. In particular, the multi-period nature of some decisions is addressed by a more comprehensivemodel, which is solved by a specially tailored heuristic approach. The numerical results suggest that the solution procedure can identify high quality solutions within reasonable computational time

Location problems with multiple criteria

This chapter analyzes multicriteria continuous, network, and discrete location problems. In the continuous framework, we provide a complete description of the set of weak Pareto, Pareto, and strict Pareto locations for a general Q-criteria location problem based on the characterization of three criteria problems. In the network case, the set of Pareto locations is characterized for general networks as well as for tree networks using the concavity and convexity properties of the distance function on the edges. In the discrete setting, the entire set of Pareto locations is characterized using rational generating functions of integer points in polytopes. Moreover, we describe algorithms to obtain the solutions sets (the different Pareto locations) using the above characterizations. We also include a detailed complexity analysis. A number of references has been cited throughout the chapter to avoid the inclusion of unnecessary technical details and also to be useful for a deeper analysis

What does the “slow” stand for? : an analysis of slow journalism’s relationship with time

O objetivo deste texto é iniciar uma investigação sobre a temporalidade do slow journalism. Partimos de definições formuladas em âmbito acadêmico e analisamos produtos jornalísticos que são considerados parte do movimento. Recorremos à tipologia desenvolvida por Charron e Bonville, que descreve o jornalismo de transmissão, opinião, informação e comunicação, para observar, entre outros elementos, a relação de cada modelo com o tempo. Concluímos que, assim como no movimento slow food, as questões éticas se mostram mais relevantes ao slow journalism do que propriamente sua relação com o tempo.The purpose of this paper is to investigate the temporality of slow journalism. We review academic approaches and describe some of the journalistic products that are considered part of the movement. We use the typology developed by Charron and Bonville, which describes transmission,opinion, information and communication journalism, to observe, among other elements, the relationship of each ideal type with time. We conclude that, as in the slow food movement, ethical issues are more relevant to slow journalism than its relationship to time

Pregnant women with bronchial asthma benefit from progressive muscle relaxation: A randomized, prospective, controlled trial

Background: Asthma is a serious medical problem in pregnancy and is often associated with stress, anger and poor quality of life. The aim of this study was to determine the efficacy of progressive muscle relaxation (PMR) on change in blood pressure, lung parameters, heart rate, anger and health-related quality of life in pregnant women with bronchial asthma. Methods: We treated a sample of 64 pregnant women with bronchial asthma from the local population in an 8-week randomized, prospective, controlled trial. Thirty-two were selected for PMR, and 32 received a placebo intervention. The systolic blood pressure, forced expiratory volume in the first second, peak expiratory flow and heart rate were tested, and the State-Trait Anger Expression Inventory and Health Survey (SF-36) were employed. Results: According to the intend-to-treat principle, a significant reduction in systolic blood pressure and a significant increase in both forced expiratory volume in the first second and peak expiratory flow were observed after PMR. The heart rate showed a significant increase in the coefficient of variation, root mean square of successive differences and high frequency ranges, in addition to a significant reduction in low and middle frequency ranges. A significant reduction on three of five State-Trait Anger Expression Inventory scales, and a significant increase on seven of eight SF-36 scales were observed. Conclusions: PMR appears to be an effective method to improve blood pressure, lung parameters and heart rate, and to decrease anger levels, thus enhancing health-related quality of life in pregnant women with bronchial asthma. Copyright (c) 2006 S. Karger AG, Basel

OS IMPACTOS DA REFORMA DO ENSINO MÉDIO EM UMA EDUCAÇÃO EMANCIPADORA E VOLTADA PARA AS HUMANIDADES

O presente artigo aborda os seguintes temas: no primeiro capítulo, aborda a necessidade de se ter uma educação mais voltada para as humanidades (de acordo com Martha Nussbaum) que se preocupa menos com as tecnologias e mais com o aspecto da formação do indivíduo, para que esse seja capaz de ver o outro e assim auxilie na construção de uma melhor democracia, bem como aponta para a necessidade de que a educação seja emancipadora (de acordo com Paulo Freire em contrapartida a uma educação bancária). No segundo capítulo faz um traçado sobre a Reforma do ensino médio instituída pela Lei 13.415/16 e da instituição da Base Nacional Comum Curricular – BNCC que juntos representaram a retirada da obrigatoriedade de inúmeras disciplinas (justamente aquelas que a teoria das humanidades vai defender ferrenhamente) - do currículo do ensino médio, as diluindo em ações esparsas. Levando em consideração os dois pontos abordados, o texto passa para a conclusão de que tal reforma é bastante prejudicial para a educação brasileira

ESCOLAS FAMÍLIAS AGRÍCOLAS: UMA DEMONSTRAÇÃO DA NATUREZA COOPERATIVA E COMUNITÁRIA DO HOMEM

A ideia de que o ser humano é por natureza egoísta, propenso ao conflito e que tende sempre a buscar o prazer e fugir da dor é, na primeira parte do trabalho, desmistificada através de autores como Piotr Kropotkin, Samuel Bowles, Herbert Gintis e Yuval Noah Harari. A segunda parte do trabalho aborda o comunitarismo, que tem como um de seus expoentes, Amitai Etzioni. Referida abordagem trabalha a partir do equilíbrio entre Estado, mercado e comunidade. Por fim, a terceira parte do trabalho, aborda as Escolas Famílias Agrícolas – EFAS, como expressão do comunitarismo

Detecção de isolados do Grapevine fanleaf virus em videiras por meio de testes sorológico e molecular.

A degenerescência da videira, causada pelo Grapevine fanleaf virus (GFLV), ocorre na maioria dos países vitícolas, causando relevantes danos

Estudo in silico de sítios de restrição enzimática de genes da proteína capsidial e análise de diversidade genética de Apple chlorotic leaf spot virus em fruteiras de semente e caroço.

Cultivares comerciais de macieiras são infectadas por 3 espécies principais de vírus: Apple chlorotic leaf spot virus (ACLSV), Apple stem grooving virus (ASGV) e Apple stem pitting virus (ASPV), geralmente em infecções complexas. O objetivo do estudo foi caracterizar a diversidade genética de genes da proteína capsidial (CP) de isolados de ACLSV.(Embrapa Uva e Vinho. Documentos, 99