Six-coordinate organotin(IV) complexes formed using the Kläui ligands; [CpCo{P(OR′)2O}3]SnR3 − nCln

The complexes [CpCo{P(OR′)2O}3]SnR3 − nCln [R′ = Me, Et; R = Ph, Me] are readily prepared from the corresponding organotin chloride and the sodium salt of the Kläui ligands. The X-ray crystal structures of the full series are reported for R = Ph, n = 0-3, and these show that they are all six-coordinate, including the Ph3Sn derivative which is the first example of a SnC3O3 coordination sphere. 1H, 13C, 31P and 119Sn NMR spectra are reported, and interpreted in terms of significant second-order effects and fluxional processes

Novel six-coordinate Aryl- and Alkyltin complexes

Organo-tin compounds have wide applications as pesticides and as intermediates for organic synthesis.¹ They are invariably Sn(IV) derivatives and are generally four-coordinate.² The mixed organo/chioro compounds of the type RnSnCI4-n do however have the ability to expand their coordination numbers to five or six. This depends critically on the substituents - with four organic groups, R₄Sn, there is no tendency at all to coordinate extra ligands, while at the other extreme SnCl₄ readily forms six-coordinate [SnC1₄L₂] complexes since the electronegative halo groups increase the Lewis acidity of the tin centre

Electroweak Theory Without Higgs Bosons

A perturbative SU(2)_L X U(1)_Y electroweak theory containing W, Z, photon, ghost, lepton and quark fields, but no Higgs or other fields, gives masses to W, Z and the non-neutrino fermions by means of an unconventional choice for the unperturbed Lagrangian and a novel method of renormalisation. The renormalisation extends to all orders. The masses emerge on renormalisation to one loop. To one loop the neutrinos are massless, the A -> Z transition drops out of the theory, the d quark is unstable and S-matrix elements are independent of the gauge parameter xi.Comment: 27 pages, LaTex, no figures; revised for publication; accepted by Int. J. Mod. Phys. A; includes biographical note on A. F. Nicholso

Pleural mesothelioma and lung cancer risks in relation to occupational history and asbestos lung burden.

BACKGROUND: We have conducted a population-based study of pleural mesothelioma patients with occupational histories and measured asbestos lung burdens in occupationally exposed workers and in the general population. The relationship between lung burden and risk, particularly at environmental exposure levels, will enable future mesothelioma rates in people born after 1965 who never installed asbestos to be predicted from their asbestos lung burdens. METHODS: Following personal interview asbestos fibres longer than 5 µm were counted by transmission electron microscopy in lung samples obtained from 133 patients with mesothelioma and 262 patients with lung cancer. ORs for mesothelioma were converted to lifetime risks. RESULTS: Lifetime mesothelioma risk is approximately 0.02% per 1000 amphibole fibres per gram of dry lung tissue over a more than 100-fold range, from 1 to 4 in the most heavily exposed building workers to less than 1 in 500 in most of the population. The asbestos fibres counted were amosite (75%), crocidolite (18%), other amphiboles (5%) and chrysotile (2%). CONCLUSIONS: The approximate linearity of the dose-response together with lung burden measurements in younger people will provide reasonably reliable predictions of future mesothelioma rates in those born since 1965 whose risks cannot yet be seen in national rates. Burdens in those born more recently will indicate the continuing occupational and environmental hazards under current asbestos control regulations. Our results confirm the major contribution of amosite to UK mesothelioma incidence and the substantial contribution of non-occupational exposure, particularly in women

Twenty-three Species of Hypobarophilic Bacteria Recovered from Diverse Ecosystems Exhibit Growth under Simulated Martian Conditions at 0.7 kPa

Bacterial growth at low pressure is a new research area with implications for predicting microbial activity in clouds, the bulk atmosphere on Earth, and for modeling the forward contamination of planetary surfaces like Mars. Here we describe experiments on the recovery and identification of 23 species of bacterial hypobarophiles (def., growth under hypobaric conditions of approximately 1-2 kPa) in 11 genera capable of growth at 0.7 kPa. Hypobarophilic bacteria, but not archaea or fungi, were recovered from soil and non-soil ecosystems. The highest numbers of hypobarophiles were recovered from Arctic soil, Siberian permafrost, and human saliva. Isolates were identified through 16S rRNA sequencing to belong to the genera Carnobacterium, Exiguobacterium, Leuconostoc, Paenibacillus, and Trichococcus. The highest population of culturable hypobarophilic bacteria (5.1 x 104 cfu/g) was recovered from Colour Lake soils from Axel Heiberg Island in the Canadian arctic. In addition, we extend the number of hypobarophilic species in the genus Serratia to 6 type-strains that include S. ficaria, S. fonticola, S. grimesii, S. liquefaciens, S. plymuthica, and S. quinivorans. Microbial growth at 0.7 kPa suggests that pressure alone will not be growth-limiting on the martian surface, or in Earth's atmosphere up to an altitude of 34 km

Smallholder dairying under transactions costs in East Africa

In peri-urban areas of the world where cattle are present, dairy farming has typically been part of the adjustment in production patterns of smallholders faced with shrinking arable land, higher population density and rising wage rates. In sub-Saharan Africa, where the economic viability of smallholder agriculture has come under increasing pressure, smallholder peri-urban dairy development has not been widespread outside of the East African highlands. Understanding the nature of constraints limiting smallholder peri-urban dairying so as to promote this activity and improve the livelihoods of smallholders is, therefore, a key public policy issue for African countries. It is argued that dairying is vital to future viability of many small farms in East Africa and that high transactions costs for dairy production and marketing limit participation by asset- and information-poor smallholders. Case studies from Kenya and Ethiopia illustrate the role of dairy cooperatives in reducing transactions costs. Analysis of the determinants of producer prices received by a sample of dairy producers near Addis Ababa suggests that different levels of access to infrastructure, assets, and information explain why they contemporaneously accept widely different producer prices for fluid milk

The epidemiology of the first wave of H1N1 influenza pandemic in Australia : a population-based study

Objectives: Following the recent H1N1 influenza pandemic we were able to describe seropositivity in a repre-sentative sample of adults prior to the availability of a specific vaccine.Methods: This cross-sectional serological study is set in the Barwon Statistical Division, Australia. Blood samples were collected from September 2009 through to May 2010, from 1184 individuals (569 men, 615 women; median age 61.7 years), randomly selected from electoral rolls. Serum was analysed for specific H1N1 immunity using a haemagglutina-tion inhibition test. A self-report provided information about symptoms, demographics and healthcare. Associations be-tween H1N1 infection, gender, households and occupation were determined using logistic regression, adjusting for age.Results: Of 1184 individuals, 129 (58 men, 71 women) were seropositive. Gender-adjusted age-specific prevalence was: 8.3% 20-29 years, 13.5% 30-39, 10.4% 40-49, 6.5% 50-59, 9.7% 60-69, 10.3% 70-79, 18.8% 80+. Standardised preva-lence was 10.3% (95%CI 9.6-11.0). No associations were detected between seropositivity and gender (OR=0.82, 95%CI 0.57-1.19) or being a healthcare worker (OR=1.43, 95%CI 0.62-3.29). Smokers (OR=1.86, 95%CI 1.09-3.15) and those socioeconomically disadvantaged (OR=2.52, 95%CI 1.24-5.13) were at increased risk. Among 129 seropositive individu-als, 31 reported symptoms that were either mild (n = 13) or moderate (time off work, doctor visit, n = 18). For age &lt;60, 39.6% of seropositive individuals reported symptoms, whereas the proportion was 13.2% for age 60+.Conclusions: Following the pandemic, the proportion of seropositive adults was low, but significant subclinical infection was found. Social disadvantage increased the likelihood of infection. The low symptom rate for older ages may relate to pre-existing immunity.<br /

Correlations, fluctuations and stability of a finite-size network of coupled oscillators

The incoherent state of the Kuramoto model of coupled oscillators exhibits marginal modes in mean field theory. We demonstrate that corrections due to finite size effects render these modes stable in the subcritical case, i.e. when the population is not synchronous. This demonstration is facilitated by the construction of a non-equilibrium statistical field theoretic formulation of a generic model of coupled oscillators. This theory is consistent with previous results. In the all-to-all case, the fluctuations in this theory are due completely to finite size corrections, which can be calculated in an expansion in 1/N, where N is the number of oscillators. The N -> infinity limit of this theory is what is traditionally called mean field theory for the Kuramoto model.Comment: 25 pages (2 column), 12 figures, modifications for resubmissio

Using System Dynamics Modelling Approach to Develop Management Tools for Animal Production with Emphasis on Small Ruminants

Small ruminants are important assets in several regions of the world. They account for more than half of the domesticated ruminants. Despite the growth in goat production in the world (more than 2% per year), research related to goat production is less than desired. One underused but potentially valuable approach for research on small ruminants is simulation modelling. Models of the components of small ruminant systems can enhance the financial returns and reduce negative environmental impacts. These models can be used to assess many dimensions of small ruminant production, from rumen dynamics to economic policies designed to support small ruminant production. Understanding the nutrition, production, and economic policy feedback signals and planning ahead is crucial to build a robust and integrated production activity that can be managed under different production scenarios. System Dynamics (SD) is a computer-aided modelling methodology that can be used to perform policy analysis and decision support system (DSS) applied to dynamic problems arising in complex social, managerial, economic, or ecological dynamic systems characterized by interdependence, mutual interaction, information feedback, and circular causality. SD can be used as a modelling tool to aggregate knowledge to solve different types of problems that have a limited scope to a specific location or have broad trends of applications across locations and areas of science. Important issues of broad application include the bearings of animal production in the climate change and the impacts of climate change in animal production, alternative production scenarios of animal and crop integration, associations between animal production and business (economics, marketing). The trend of increasing small ruminants in tropical and subtropical regions and an increasing pressure on tropical and subtropical livestock systems to produce food, to feed livestock, and to produce energy crops warrants the development of DSS to address issues such as what is the “real” benefits of livestock, the negative impacts livestock can have on greenhouse-gas emissions and the environment, and the effects of climate change on livestock systems

Chaotic saddles in nonlinear modulational interactions in a plasma

A nonlinear model of modulational processes in the subsonic regime involving a linearly unstable wave and two linearly damped waves with different damping rates in a plasma is studied numerically. We compute the maximum Lyapunov exponent as a function of the damping rates in a two-parameter space, and identify shrimp-shaped self-similar structures in the parameter space. By varying the damping rate of the low-frequency wave, we construct bifurcation diagrams and focus on a saddle-node bifurcation and an interior crisis associated with a periodic window. We detect chaotic saddles and their stable and unstable manifolds, and demonstrate how the connection between two chaotic saddles via coupling unstable periodic orbits can result in a crisis-induced intermittency. The relevance of this work for the understanding of modulational processes observed in plasmas and fluids is discussed.Comment: Physics of Plasmas, in pres