2,358 research outputs found

    Challenges of Student Engagement in Community Colleges

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    Student engagement is a major challenge faced by community college administrators. The impact of low student engagement on retention and graduation rates means community colleges across the nation have the opportunity to re-evaluate policies and practices that contribute to or hinder a student culture of engagement (Greene, Marti, & McClenney, 2008; McClenney, 2007). Community colleges are host to a diverse student population including commuter students, non-traditional students, and students with a wide range of academic goals and academic preparedness. The diversity of this population provides a challenging environment in which to foster student engagement. The function and value of student affairs are often diminished on community college campuses with less emphasis on co-curricular student development. This article will review existing literature of challenges faced by community colleges and the role of student affairs in the unique environment of community colleges. The article will conclude with recommendations for developing institution-wide efforts to support student engagement and topics for further research

    Complex group algebras of the double covers of the symmetric and alternating groups

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    We prove that the double covers of the alternating and symmetric groups are determined by their complex group algebras. To be more precise, let n≄5n\geq 5 be an integer, GG a finite group, and let \AAA and \SSS^\pm denote the double covers of \Al_n and \Sy_n, respectively. We prove that \CC G\cong \CC \AAA if and only if G\cong \AAA, and \CC G\cong \CC \SSS^+\cong\CC\SSS^- if and only if G\cong \SSS^+ or \SSS^-. This in particular completes the proof of a conjecture proposed by the second and fourth authors that every finite quasi-simple group is determined uniquely up to isomorphism by the structure of its complex group algebra. The known results on prime power degrees and relatively small degrees of irreducible (linear and projective) representations of the symmetric and alternating groups together with the classification of finite simple groups play an essential role in the proofs.Comment: 27 pages, the previous version is revised slightly, to appear in Algebra & Number Theor

    A perspective on the impact of radiation therapy on the immune rheostat.

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    The advent and success of immune checkpoint inhibitors (ICIs) in cancer treatment has broadened the spectrum of tumours that might be considered "immunogenic" and susceptible to immunotherapeutic (IT) intervention. Not all cancer types are sensitive, and not all patients with any given type respond. Combination treatment of ICIs with an established cytotoxic modality such as radiation therapy (RT) is a logical step towards improvement. For one, RT alone has been shown to be genuinely immunomodulatory and secondly pre-clinical data generally support combined ICI-RT approaches. This new integrated therapy for cancer treatment holds much promise, although there is still a lot to be learned about how best to schedule the treatments, manage the toxicities and determine what biomarkers might predict response, as well as many other issues. This review examines how RT alters the immune rheostat and how it might best be positioned to fully exploit IT

    The role of teamwork and non-technical skills for improving emergency surgical outcomes: an international perspective

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    The assurance of patient safety in emergency general surgery remains challenging due to the patients' high-risk underlying conditions and the wide variability in emergency surgical care provided around the globe. The authors of this article convened as an expert panel on patient safety in surgery at the 8(th) International Conference of the World Society of Emergency Surgery (WSES) in Edinburgh, Scotland, on September 7-10, 2021. This review article represents the proceedings from the expert panel discussions at the WSES congress and was designed to provide an international perspective on optimizing teamwork and non-technical skills in emergency general surgery

    Malignancies in Prader-Willi Syndrome:Results From a Large International Cohort and Literature Review

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    CONTEXT: Prader-Willi syndrome (PWS) is a complex disorder combining hypothalamic dysfunction, neurodevelopmental delay, hypotonia, and hyperphagia with risk of obesity and its complications. PWS is caused by the loss of expression of the PWS critical region, a cluster of paternally expressed genes on chromosome 15q11.2-q13. As life expectancy of patients with PWS increases, age-related diseases like malignancies might pose a new threat to health. OBJECTIVE: To investigate the prevalence and risk factors of malignancies in patients with PWS and to provide clinical recommendations for cancer screening. METHODS: We included 706 patients with PWS (160 children, 546 adults). We retrospectively collected data from medical records on past or current malignancies, the type of malignancy, and risk factors for malignancy. Additionally, we searched the literature for information about the relationship between genes on chromosome 15q11.2-q13 and malignancies. RESULTS: Seven adults (age range, 18-55 years) had been diagnosed with a malignancy (acute lymphoblastic leukemia, intracranial hemangiopericytoma, melanoma, stomach adenocarcinoma, biliary cancer, parotid adenocarcinoma, and colon cancer). All patients with a malignancy had a paternal 15q11-13 deletion. The literature review showed that several genes on chromosome 15q11.2-q13 are related to malignancies. CONCLUSION: Malignancies are rare in patients with PWS. Therefore, screening for malignancies is only indicated when clinically relevant symptoms are present, such as unexplained weight loss, loss of appetite, symptoms suggestive of paraneoplastic syndrome, or localizing symptoms. Given the increased cancer risk associated with obesity, which is common in PWS, participation in national screening programs should be encouraged.</p

    Genomic Responses to Abnormal Gene Dosage: The X Chromosome Improved on a Common Strategy

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    This new primer, which discusses a study by Zhang et al., provides an overview of the process by which chromosomes achieve dose compensation and the mechanisms underlying this phenomenon in Drosophila S2 cells
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