The Einstein-scalar field Lichnerowicz equations on compact Riemannian manifolds

Ph.DDOCTOR OF PHILOSOPH

Deep Energy Autoencoder for Noncoherent Multicarrier MU-SIMO Systems

We propose a novel deep energy autoencoder (EA) for noncoherent multicarrier multiuser single-input multipleoutput (MU-SIMO) systems under fading channels. In particular, a single-user noncoherent EA-based (NC-EA) system, based on the multicarrier SIMO framework, is first proposed, where both the transmitter and receiver are represented by deep neural networks (DNNs), known as the encoder and decoder of an EA. Unlike existing systems, the decoder of the NC-EA is fed only with the energy combined from all receive antennas, while its encoder outputs a real-valued vector whose elements stand for the subcarrier power levels. Using the NC-EA, we then develop two novel DNN structures for both uplink and downlink NC-EA multiple access (NC-EAMA) schemes, based on the multicarrier MUSIMO framework. Note that NC-EAMA allows multiple users to share the same sub-carriers, thus enables to achieve higher performance gains than noncoherent orthogonal counterparts. By properly training, the proposed NC-EA and NC-EAMA can efficiently recover the transmitted data without any channel state information estimation. Simulation results clearly show the superiority of our schemes in terms of reliability, flexibility and complexity over baseline schemes.Comment: Accepted, IEEE TW

Trajectory Tracking Control Design for Dual-Arm Robots Using Dynamic Surface Controller

This paper presents a dynamic surface controller (DSC) for dual-arm robots (DAR) tracking desired trajectories. The DSC algorithm is based on backstepping technique and multiple sliding surface control principle, but with an important addition. In the design of DSC, low-pass filters are included which prevent the complexity in computing due to the “explosion of terms”, i.e. the number of terms in the control law rapidly gets out of hand. Therefore, a controller constructed from this algorithm is simulated on a four degrees of freedom (DOF) dual-arm robot with a complex kinetic dynamic model. Moreover, the stability of the control system is proved by using Lyapunov theory. The simulation results show the effectiveness of the controller which provide precise tracking performance of the manipulator

Serum interleukin 6 concentration in patients with pemphigus

Pemphigus is a rare autoimmune blistering disease that detrimentally affects the integumentary system and decreases patients’ quality of life. Recent studies have shown that interleukin 6 (IL-6) is closedly involved in the immunophathogenesis of pemphigus. Therefore, this study was performed to evaluate the role of IL-6 in the pathogenesis and severity of pemphigus disease. The case-series study was conducted in Ho Chi Minh City Hospital of Dermato-Venereology from January 2022 to August 2022, involving 26 patients with pemphigus vulgaris (PV), 4 patients with pemphigus foliaceus (PF), and 20 healthy volunteers. The serum IL-6 concentrations of patients with PV and PF were significantly higher than those of the healthy volunteers (P < 0.001). Serum IL-6 concentrations were significantly higher in patients with a positive than a negative Nikolsky sign (P < 0.001). A significant correlation was found between the serum IL-6 concentration and the pemphigus disease area index (r = 0.8, P < 0.001). Our results suggest that IL-6 may play an important role in the pathogenesis and severity of pemphigus. Therefore, new therapies targeting IL-6 may be a promising choice for treating pemphigus, especially in its severe forms

Immunohistochemical expression of anaplastic lymphoma kinase in neuroblastoma and its relations with some clinical and histopathological features

Background Anaplastic lymphoma kinase (ALK) mutations have been identified as a prominent cause of some familial and sporadic neuroblastoma (NB). ALK expression in NB and its relationship with clinical and histopathological features remains controversial. This study investigated ALK expression and its potential relations with these features in NB. Methods Ninety cases of NB at the Department of Pathology, University of Medicine and Pharmacy at Ho Chi Minh City, Viet Nam from 01/01/2018 to 12/31/2021, were immunohistochemically stained with ALK (D5F3) antibody. The ALK expression and its relations with some clinical and histopathological features were investigated. Results The rate of ALK expression in NB was 91.1%. High ALK expression (over 50% of tumor cells were positive with moderate-strong intensity) accounted for 65.6%, and low ALK expression accounted for 34.4%. All the MYCN-amplified NB patients had ALK immunohistochemistry positivity, most cases had high ALK protein expression. The undifferentiated subtype of NB had a lower ALK-positive rate than the poorly differentiated and differentiated subtype. The percentages of ALK positivity were significantly higher in more differentiated histological types of NB (p = .024). There was no relation between ALK expression and: age group, sex, primary tumor location, tumor stage, MYCN status, clinical risk, Mitotic-Karyorrhectic Index, prognostic group, necrosis, and calcification. Conclusions ALK was highly expressed in NB. ALK expression was not related to several clinical and histopathological features. More studies are needed to elucidate the association between ALK expression and ALK gene status and to investigate disease progression, especially the oncogenesis of ALK-positive NB

Disinfection performance of an ultraviolet lamp: a CFD investigation

Ultraviolet (UV)-based devices have shown their effectiveness on various germicidal purposes. To serve their design optimisation, the disinfection effectiveness of a vertically cylindrical UV lamp, whose wattage ranges from P = 30 − 100 W, is numerically investigated in this work. The UV radiation is solved by the Finite Volume Method together with the Discrete Ordinates model. Various results for the UV intensity and its bactericidal effects against several popular virus types, i.e., Corona-SARS, Herpes (type 2), and HIV, are reported and analysed in detail. Results show that the UV irradiance is greatly dependent on the lamp power. Additionally, it is indicated that the higher the lamp wattage employed, the larger the bactericidal rate is observed, resulting in the greater effectiveness of the UV disinfection process. Nevertheless, the wattage of P ≤ 100W is determined to be insufficient for an effective disinfection performance in a whole room; higher values of power must hence be considered in case intensive sterilization is required. Furthermore, the germicidal effect gets reduced with the viruses less sensitive to UV rays, e.g, the bactericidal rate against the HIV virus is only ∼8.98% at the surrounding walls

Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety.

International audienceIn this Letter, we report a convenient and efficient method for the synthesis of new simplified derivatives of hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groups as Michael acceptor. Most of these derivatives have a strong cytotoxic activity on three human tumor cell lines (KB, Hep-G2 and MCF7). Analogs 17b and 17f showed a high cytotoxicity against KB and Hep-G2 cancer cell lines comparable to paclitaxel and ellipticine

Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity

International audienceIn this article, we report a convenient and efficient method for the synthesis of new simplified derivativesof hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groupsas Michael acceptor. Most of these derivatives have a strong cytotoxic activity on three human tumorcell lines (KB, Hep-G2 and MCF7). Analogs 17b and 17f showed a high cytotoxicity against KB andHep-G2 cancer cell lines comparable to paclitaxel and ellipticine

Studying and forecasting the evolution of the Day river coastal zone up to the year of 2070

The Day river coastal zone is the place of plentiful and eventful economical activities and the natural habitat of diverse endemic species that should be preserved and developed. According to the updated geological, remote-sensing and oceanographic data sources, this study figures out the actual state, evolutional history and forecasts the development of the Day river coastal zone up to the year 2070, which could be used to improve the effectiveness of the long-term spatial coastal zone management and master planning. Major conclusions are as follows: (i) The Day river coastline has been highly modified since the last 50 years, (ii) The shoreline seaward development tends to gradually decrease in recent years, and (iii) The river-bed continues to be shifted southwestwards in the context of global climate change and sea level rise.Abstract STUDYING AND FORECASTING THE EVOLUTION OF THE DAY RIVER COASTAL ZONE UPTO THE YEAR 2050 Duong Quoc Hung1, Vu Hai Dang1, Phan Dong Pha1, Nguyen Thi Anh Nguyet1, Ngo Bich Huong1, Nguyen Thai Son2 (1) Institute of Marine Geology and Goephysics; (2) Institute of Geography The coastal geographical features including alluvial grouds, estuaries, mangrove forest, etc. are products of the river - ocean interactions, reflect the dynamic equilibrium of the unsustainable ecosystems that are spacial and temporary changing. These areas are also the places of plentiful and eventful economical activities and the natural diversified endemic habitats to be preserved and developed. According to the updated data sources, this study mentions to the actual state, evolution history and developing forecasts for the Day River coastal zone up to the year of 2050, which could be used to inhale the effectiveness of the long-term spacial coastal zone management and master plannin