Public Acceptability in the UK and USA of Nudging to Reduce Obesity: The Example of Reducing Sugar-Sweetened Beverages Consumption

published_or_final_versio

Ready for 21st-century Education – Pre-service Music Teachers Embracing ICT to Foster Student-centered Learning

AbstractThere is always competition for curriculum time for pre-service teachers, especially in teaching methods courses. This study explored whether pre-service teachers are prepared to learn from each other online. It looked at 47 students taking a course entitled “Music Education Methods and Strategies”. Each was required to design a game as a form of pedagogy in music education and to upload it to a learning management system (LMS). They then had to read and comment on all submissions and vote for the best three games. After doing so, the students completed an online survey about their experiences. Thirty-nine valid questionnaires were submitted, giving a response rate of 83%. It is very encouraging to note that the students gave all questions a high rating (scoring them 3 or above on a 5-point Likert-type scale). The two top-rated items confirmed that the students felt responsible for their own learning and competent in using a LMS. This suggests that pre-service music teachers are ready for 21st-century education using information and communications technology to develop learner-centered activities

‘It’s my right to play too!’ Play for disabled children in Taiwan and Hong Kong

info:eu-repo/semantics/publishedVersio

Cerebrofaciothoracic dysplasia: four new patients with a recurrent TMCO1 pathogenic variant.

Biallelic loss of function variants in the TMCO1 gene have been previously demonstrated to result in cerebrofaciothoracic dysplasia (CFTD; MIM #213980). The phenotype of this condition includes severe intellectual disability, as well as distinctive craniofacial features, including brachycephaly, synophrys, arched eyebrows, "cupid's bow" upper lip, and microdontia. In addition, nonspecific skeletal anomalies are common, including bifid ribs, scoliosis, and spinal fusion. Only 19 molecularly confirmed patients have been previously described. Here, we present four patients with CFTD, including three brothers from a Pakistani background and an additional unrelated white Scottish patient. All share the characteristic craniofacial appearance, with severe intellectual disability and skeletal abnormalities. We further define the phenotype with comparison to the published literature, and present images to define the dysmorphic features in a previously unreported ethnic group. All of our patient series are homozygous for the same c.292_293del (p.Ser98*) TMCO1 pathogenic variant, which has been previously reported only in an isolated Amish population. Thus we provide evidence that CFTD may be more common than previously thought. The patients presented here further delineate the phenotypic spectrum of CFTD and provide evidence for a recurrent pathogenic variant in TMCO1

Phenomenology of the superconducting state in Sr2RuO4

The symmetry of the superconducting phase of Sr2RuO4 is identified as the odd-parity pairing state d(k)=\hat{z}(k_x \pm i k_y) based on recent experiments. The experimental evidence for the so-called orbital dependent superconductivity leads to a single-band description of superconductivity based on spin fluctuation mechanism. It is shown that the state \hat{z}(k_x \pm i k_y) can be stabilized by the spin fluctuation feedback mechanism analogous to the A-phase in 3He and by spin-orbit coupling effects.Comment: 7 pages, 1 figure, to be published in Proc. of the conference "Anomalous Complex Superconductors" (Crete, 1998

Air-clad holmium-doped silica fiber laser

Date of Publication : 10 December 2015We report the design, fabrication, and operation of an air-clad holmium-doped fiber laser that was manufactured by directly milling the rare-earth-doped preform. This silica fiber laser operates at 2.1 μm with a slope efficiency of 49.7%, and is in-band pumped with a 1.94-μm thulium fiber laser. To the best of our knowledge, this is the first demonstration of an air-clad holmium-doped fiber laser.Sebastian W. S. Ng, David G. Lancaster, Tanya M. Monro, Peter C. Henry, and David J. Ottawa

The regulation of miRNAs by reconstituted high-density lipoproteins in diabetes-impaired angiogenesis

Diabetic vascular complications are associated with impaired ischaemia-driven angiogenesis. We recently found that reconstituted high-density lipoproteins (rHDL) rescue diabetes-impaired angiogenesis. microRNAs (miRNAs) regulate angiogenesis and are transported within HDL to sites of injury/repair. The role of miRNAs in the rescue of diabetes-impaired angiogenesis by rHDL is unknown. Using a miRNA array, we found that rHDL inhibits hsa-miR-181c-5p expression in vitro and using a hsa-miR-181c-5p mimic and antimiR identify a novel anti-angiogenic role for miR-181c-5p. miRNA expression was tracked over time post-hindlimb ischaemic induction in diabetic mice. Early post-ischaemia when angiogenesis is important, rHDL suppressed hindlimb mmu-miR-181c-5p. mmu-miR-181c-5p was not detected in the plasma or within HDL, suggesting rHDL specifically targets mmu-miR-181c-5p at the ischaemic site. Three known angiogenic miRNAs (mmu-miR-223-3p, mmu-miR-27b-3p, mmu-miR-92a-3p) were elevated in the HDL fraction of diabetic rHDL-infused mice early post-ischaemia. This was accompanied by a decrease in plasma levels. Only mmu-miR-223-3p levels were elevated in the hindlimb 3 days post-ischaemia, indicating that rHDL regulates mmu-miR-223-3p in a time-dependent and site-specific manner. The early regulation of miRNAs, particularly miR-181c-5p, may underpin the rescue of diabetes-impaired angiogenesis by rHDL and has implications for the treatment of diabetes-related vascular complications

Theory for Metal Hydrides with Switchable Optical Properties

Recently it has been discovered that lanthanum, yttrium, and other metal hydride films show dramatic changes in the optical properties at the metal-insulator transition. Such changes on a high energy scale suggest the electronic structure is best described by a local model based on negatively charged hydrogen (H$^-$) ions. We develop a many-body theory for the strong correlation in a H$^-$ ion lattice. The metal hydride is described by a large $U$-limit of an Anderson lattice model. We use lanthanum hydride as a prototype of these compounds, and find LaH$_3$ is an insulator with a substantial gap consistent with experiments. It may be viewed either as a Kondo insulator or a band insulator due to strong electron correlation. A H vacancy state in LaH$_3$ is found to be highly localized due to the strong bonding between the electron orbitals of hydrogen and metal atoms. Unlike the impurity states in the usual semiconductors, there is only weak internal optical transitions within the vacancy. The metal-insulator transition takes place in a band of these vacancy states.Comment: 18 pages, 16 figures and 6 tables. Submitted to PR

Magnetic ordering in Sr2RuO4 induced by nonmagnetic impurities

We report unusual effects of nonmagnetic impurities on the spin-triplet superconductor Sr2RuO4. The substitution of nonmagnetic Ti4+ for Ru4+ induces localized-moment magnetism characterized by unexpected Ising anisotropy with the easy axis along the interlayer c direction. Furthermore, for x(Ti) > 0.03 magnetic ordering occurs in the metallic state with the remnant magnetization along the c-axis. We argue that the localized moments are induced in the Ru4+ and/or oxygen ions surrounding Ti4+ and that the ordering is due to their interaction mediated by itinerant Ru-4d electrons with strong spin fluctuations.Comment: 5 pages, 4figure