Measuring and Monitoring Cognition in the Postoperative Period

It is common for patients of all ages to experience some degree of cognitive disturbance following surgery. In most cases, impairment appears mild and is restricted to the acute post-operative period, resolving steadily and speedily. In a small number of cases, however, deficits may be more pronounced and/or endure for longer periods, significantly delaying recovery and increasing the risk of serious clinical complications. The ability to accurately measure postoperative cognition, and track recovery of function, is an important clinical task. This review explores practical and methodological issues that may confound this process, examining how best to obtain reliable and meaningful measures of cognition before and after surgery. It considers neuropsychological test selection, administration, analysis and interpretation and offers evidence-based practice points for clinicians and researchers

The Dwarfs Beyond: The Stellar-to-Halo Mass Relation for a New Sample of Intermediate Redshift Low Mass Galaxies

A number of recent challenges to the standard Lambda-CDM paradigm relate to discrepancies that arise in comparing the abundance and kinematics of local dwarf galaxies with the predictions of numerical simulations. Such arguments rely heavily on the assumption that the local dwarf and satellite galaxies form a representative distribution in terms of their stellar-to-halo mass ratios. To address this question, we present new, deep spectroscopy using DEIMOS on Keck for 82 low mass (10^7-10^9 solar masses) star-forming galaxies at intermediate redshift (z=0.2-1). For 50 percent of these we are able to determine resolved rotation curves using nebular emission lines and thereby construct the stellar mass Tully-Fisher relation to masses as low as 10^7 solar masses. Using scaling relations determined from weak lensing data, we convert this to a stellar-to-halo mass (SHM) relation for comparison with abundance matching predictions. We find a discrepancy between the propagated predictions from simulations compared to our observations, and suggest possible reasons for this as well as future tests that will be more effective.Comment: 11 pages, 7 figures, submitted to ApJ, comments welcom

The first-mover advantage in scientific publication

Mathematical models of the scientific citation process predict a strong "first-mover" effect under which the first papers in a field will, essentially regardless of content, receive citations at a rate enormously higher than papers published later. Moreover papers are expected to retain this advantage in perpetuity -- they should receive more citations indefinitely, no matter how many other papers are published after them. We test this conjecture against data from a selection of fields and in several cases find a first-mover effect of a magnitude similar to that predicted by the theory. Were we wearing our cynical hat today, we might say that the scientist who wants to become famous is better off -- by a wide margin -- writing a modest paper in next year's hottest field than an outstanding paper in this year's. On the other hand, there are some papers, albeit only a small fraction, that buck the trend and attract significantly more citations than theory predicts despite having relatively late publication dates. We suggest that papers of this kind, though they often receive comparatively few citations overall, are probably worthy of our attention.Comment: 7 pages, 3 figure

A tutorial task and tertiary courseware model for collaborative learning communities

RAED provides a computerised infrastructure to support the development and administration of Vicarious Learning in collaborative learning communities spread across multiple universities and workplaces. The system is based on the OASIS middleware for Role-based Access Control. This paper describes the origins of the model and the approach to implementation and outlines some of its benefits to collaborative teachers and learners

Network Topology of an Experimental Futures Exchange

Many systems of different nature exhibit scale free behaviors. Economic systems with power law distribution in the wealth is one of the examples. To better understand the working behind the complexity, we undertook an empirical study measuring the interactions between market participants. A Web server was setup to administer the exchange of futures contracts whose liquidation prices were coupled to event outcomes. After free registration, participants started trading to compete for the money prizes upon maturity of the futures contracts at the end of the experiment. The evolving `cash' flow network was reconstructed from the transactions between players. We show that the network topology is hierarchical, disassortative and scale-free with a power law exponent of 1.02+-0.09 in the degree distribution. The small-world property emerged early in the experiment while the number of participants was still small. We also show power law distributions of the net incomes and inter-transaction time intervals. Big winners and losers are associated with high degree, high betweenness centrality, low clustering coefficient and low degree-correlation. We identify communities in the network as groups of the like-minded. The distribution of the community sizes is shown to be power-law distributed with an exponent of 1.19+-0.16.Comment: 6 pages, 12 figure

Mean-field solution of the small-world network model

The small-world network model is a simple model of the structure of social networks, which simultaneously possesses characteristics of both regular lattices and random graphs. The model consists of a one-dimensional lattice with a low density of shortcuts added between randomly selected pairs of points. These shortcuts greatly reduce the typical path length between any two points on the lattice. We present a mean-field solution for the average path length and for the distribution of path lengths in the model. This solution is exact in the limit of large system size and either large or small number of shortcuts.Comment: 14 pages, 2 postscript figure

Interfaces (and Regional Congruence?) in Spin Glasses

We present a general theorem restricting properties of interfaces between thermodynamic states and apply it to the spin glass excitations observed numerically by Krzakala-Martin and Palassini-Young in spatial dimensions d=3 and 4. We show that such excitations, with interface dimension smaller than d, cannot yield regionally congruent thermodynamic states. More generally, zero density interfaces of translation-covariant excitations cannot be pinned (by the disorder) in any d but rather must deflect to infinity in the thermodynamic limit. Additional consequences concerning regional congruence in spin glasses and other systems are discussed.Comment: 4 pages (ReVTeX); 1 figure; submitted to Physical Review Letter

Realistic spin glasses below eight dimensions: a highly disordered view

By connecting realistic spin glass models at low temperature to the highly disordered model at zero temperature, we argue that ordinary Edwards-Anderson spin glasses below eight dimensions have at most a single pair of physically relevant pure states at nonzero low temperature. Less likely scenarios that evade this conclusion are also discussed.Comment: 18 pages (RevTeX; 1 figure; to appear in Physical Review E

Photomixotrophic growth of Rhodobacter capsulatus SB1003 on ferrous iron

This study investigates the role iron oxidation plays in the purple non-sulfur bacterium Rhodobacter capsulatus SB1003. This organism is unable to grow photoautotrophically on unchelated ferrous iron [Fe(II)] despite its ability to oxidize chelated Fe(II). This apparent paradox was partly resolved by the discovery that SB1003 can grow photoheterotrophically on the photochemical breakdown products of certain ferric iron–ligand complexes, yet whether it could concomitantly benefit from the oxidation of Fe(II) to fix CO_2 was unknown. Here, we examine carbon fixation by stable isotope labeling of the inorganic carbon pool in cultures growing phototrophically on acetate with and without Fe(II). We show that R. capsulatus SB1003, an organism formally thought incapable of phototrophic growth on Fe(II), can actually harness the reducing power of this substrate and grow photomixotrophically, deriving carbon both from organic sources and from fixation of inorganic carbon. This suggests the possibility of a wider occurrence of photoferrotrophy than previously assumed