2,814 research outputs found

    Working Effectively with Individuals who are HIV-Positive

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    This brochure is one of a series on human resources practices and workplace accommodations for persons with disabilities edited by Susanne M. Bruyère, Ph.D., CRC, Director, Employment and Disability Institute, Cornell University ILR School. This publication was written in 1994, updated in 2001 by a representative of the New York State Department of Health AIDS Institute and updated in February 2002 and May 2010 by Nellie J. Brown, M.S., CIH, Statewide Director, Workplace Health and Safety Program, New York State School of Industrial and Labor Relations, Cornell University

    That\u27s Why Darkies Were Born / words by Lev Brown and Ray Henderson

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    Cover: from George Whites Scandals; Publisher: De Sylvia Brown and Henderson (New York)https://egrove.olemiss.edu/sharris_e/1019/thumbnail.jp

    Celebratin\u27 Day In Tennessee / music by Jack Glogau; words by Lew Brown

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    Cover: drawing of a floral Pattern; photo inset of Emma Carus; Publisher: Leo Feist Inc. (New York)https://egrove.olemiss.edu/sharris_c/1071/thumbnail.jp

    Serotonin deficiency in phenylketonuria embryopathy

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    The development and evolution of PKU can be prevented by prescribing an appropriate diet at an early age. A systematic neonatal screening has been set up in most countries. However, young women suffering from PKU give birth to very severely malformed children (PKU embryopathy: microcephaly, mental retardation, hypotrophy, cardiopathy) unless they again take up the specific diet, until the PHE level has lowered down to normal, before the beginning of gestation. The treatment has to be continued at least during the first months of gestation. This management is very unpleasant and sometimes not easily accepted. The mechanism of this embryopathy is still unknown. It is possible that (I) the excess of PHE or the presence of abnormal metabolites, or (2) serotonin deficiency (which is a feature of PKU) could be responsible for the maldevelopment of the embryo. Some authors consider that serontonin has a morphogenetic role in normal embryogenesis. Previously we described an experimental animal model using in vitro culture of rat embryos in human PKU sera. Mouse embryos have been subsequently used, since they show a greater sensitivity. Malformations, consisting essentially of neural tube defects, were present in almost 100% of the embryos cultured in serum from PKU patients. Using this animal model, we tested the hypothesis of serotonin deficiency. For this purpose, mouse embryos were cultured in human serum depleted of serotonin. Under these conditions, 100% of the embryos showed oculo-neural malformations characteristic of the experimental embryopathy. These results indicate the importance of serotonin deficiency in the occurrence of PKU embryopathy

    My Gee-Gee From the Fiji Isles / music by Albert von Tilzer; words by Lew Brown

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    Cover: drawing of a woman in an exotic dress performing in a circus, as an old man looks longingly on; Publisher: Broadway Music Corporation (New York)https://egrove.olemiss.edu/sharris_d/1012/thumbnail.jp

    Underneath the Harlem Moon / music by Harry Revel; words by Mack Gordon

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    https://egrove.olemiss.edu/sharris_e/1024/thumbnail.jp

    Among My Souvenirs / music by Horatio Nicholls; words by Edgar Leslie

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    Cover: drawing of a chest filled with letters and a Rose; Publisher: De Sylvia Brown and Henderson (New York)https://egrove.olemiss.edu/sharris_d/1086/thumbnail.jp

    Multigrid elliptic equation solver with adaptive mesh refinement

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    In this paper we describe in detail the computational algorithm used by our parallel multigrid elliptic equation solver with adaptive mesh refinement. Our code uses truncation error estimates to adaptively refine the grid as part of the solution process. The presentation includes a discussion of the orders of accuracy that we use for prolongation and restriction operators to ensure second order accurate results and to minimize computational work. Code tests are presented that confirm the overall second order accuracy and demonstrate the savings in computational resources provided by adaptive mesh refinement.Comment: 12 pages, 9 figures, Modified in response to reviewer suggestions, added figure, added references. Accepted for publication in J. Comp. Phy
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