Acute hepatitis due to brucellosis: case report

Brucella infection is a systemic disease. It rarely causes local infections like hepatitis in gastrointestinal system. In this article we would like to present an acute hepatitis case related to brucella infection that followed up in our clinic. A male, 30 year-old patient hospitalized due to common muscle pain, high fever and vomiting. During the physical examination the patient’s skin, scleras and mucosal membranes were icteric, the liver was 2-3 cm palpable and tender. Laboratory findings were as follows: AST:1190 U/L; ALT:715 U/L; GGT:961 U/L; ALP:369 U/L; total bilirubin:4.6 mg/dL; direct bilirubin:2.1 mg/dL. Viral markers were found to be negative. We started treatment with streptomicine and doxicycline since, the patient’s standard brucella tube agglutination test was positive (1/60) and brucella spp produced in his blood culture. From the second day of the treatment, we started to get clinical response. On the 17th day of the treatment, he discharged from the hospital because ALT, AST and bilirubine level were found normal and his treatment was completed to the 8 weeks. Brucella is continuing to be an important health problem especially who live in surrounding countryside and have to keep in mind in the differential diagnosis of the acute hepatitis

Acute brucellosis during pegylated ınterferon alfa plus ribavirin therapy for chronic hepatitis c; case report

Pegile interferon kullanımına bağlı enfeksiyona duyarlılıkta artış gözlenmekte ve gelişen yan etkiler birçok enfeksiyon hastalığının klinik bulguları ile karışabilmektedir. Multisistem hastalık olan bruselloz, ülkemizde endemiktir. Birçok organ ve sistemi tutan sistemik bir enfeksiyon olması nedeni ile klinik bulgu ve semptomlar geniş bir spektrum oluşturur. Raporda kronik hepatit C tanısı ile izlenen hastada, PEG-IFN alfa ve ribavirin tedavisi esnasında akut bruselloz gelişimi sunulmuştur.Increased susceptibility to infections is observed due to the administration of pegylated interferon, and emergent side effects may interfere with the clinical signs of numerous infectious diseases. Brucellosis. a multi-system disease, is endemic to our country. Being a systemic infec tion involving multiple organs and systems, clinical manifestatio ns and symptoms of Brucellosis can appear in a wide spectrum. In this report. the development of acute brucellosis during treatment with PEG-IFN alfa and ribavirin in a patient diagnosed with chronic hepatitis C is presented

Acute brucellosis during pegylated ınterferon alfa plus ribavirin therapy for chronic hepatitis c; case report

Pegile interferon kullanımına bağlı enfeksiyona duyarlılıkta artış gözlenmekte ve gelişen yan etkiler birçok enfeksiyon hastalığının klinik bulguları ile karışabilmektedir. Multisistem hastalık olan bruselloz, ülkemizde endemiktir. Birçok organ ve sistemi tutan sistemik bir enfeksiyon olması nedeni ile klinik bulgu ve semptomlar geniş bir spektrum oluşturur. Raporda kronik hepatit C tanısı ile izlenen hastada, PEG-IFN alfa ve ribavirin tedavisi esnasında akut bruselloz gelişimi sunulmuştur.Increased susceptibility to infections is observed due to the administration of pegylated interferon, and emergent side effects may interfere with the clinical signs of numerous infectious diseases. Brucellosis. a multi-system disease, is endemic to our country. Being a systemic infec tion involving multiple organs and systems, clinical manifestatio ns and symptoms of Brucellosis can appear in a wide spectrum. In this report. the development of acute brucellosis during treatment with PEG-IFN alfa and ribavirin in a patient diagnosed with chronic hepatitis C is presented

An abscess due to Pasteurella multocida after a cat scratch Case report and evaluation of antibiotic prophylaxis

Pasteurella multocida has been isolated from 50% to 70% of healthy cats and most commonly associated with acute skin and soft tissue infections following an animal bite or scratch. As the zone and depth of injury can lead to more serious infections such as deep tissue infections, septic arthritis, osteomyelitis. However, no predictive factor showing which wound would be infected. In our case, patient whom applied with abscess after a cat scratch and P. multocida was found as a causative agent. This situation has caused to review us, once more, that which cases should be taken antibiotic pro­phylaxis in addition to immunoprophylaxis (for rabies post-exposure prophylaxis, and anti-tetanus prophylaxis) in the first admission. Antibiotic prophylaxis should be used for 3-5 days in selected cases if they include; moderate to severe crushing injuries especially edematous form, less than 8 hours old, bone or joint penetration, hand wounds, especially emphasizes the importance of hand injuries and deep penetrations. J Microbiol Infect Dis 2014; 4(4): 159-16

The clinical and laboratory characteristics, treatments, and outcomes of patients with Brucella epididymo-orchitis (BEO) compared to those without BEO

Background/aim: We aim to describe the clinical and laboratory characteristics, treatment, and outcomes of 21 patients with Brucella epididymo-orchitis (BEO) from Eskisehir Yunus Emre State Hospital, Turkey

Two Cases of Crimean-Congo Hemorrhagic Fever: Delayed Diagnosis

Crimean-Congo hemorrhagic fever (CCHF) is an acute and severe tick-borne viral disease presenting with fever and hemorrhage. Since 2002, CCHF cases have been observed in Turkey, and the cases have significantly increased over the years. Most of the cases are reported from hinterland of the Black Sea region and in a large geographical area between North Central and Northeastern Anatolia, especially during spring and summer. If people, especially those living in rural areas or dealing with agriculture and stockbreeding, have complaints of acute fever, headache, abdominal pain, nausea, vomiting, and rash, their history of tick contact should be reviewed and CCHF should be considered. In this study, we present two cases from the Eskisehir region who admitted with non-specific symptoms and different preliminary diagnoses, and who were later diagnosed with CCHF