O(2) symmetry breaking vs. vortex loop percolation

We study with lattice Monte Carlo simulations the relation of global O(2) symmetry breaking in three dimensions to the properties of a geometrically defined vortex loop network. We find that different definitions of constructing a network lead to different results even in the thermodynamic limit, and that with typical definitions the percolation transition does not coincide with the thermodynamic phase transition. These results show that geometrically defined percolation observables need not display universal properties related to the critical behaviour of the system, and do not in general survive in the field theory limit.Comment: 14 pages; references added, version to appear in Phys.Lett.

The inverted XY universality of the superconductivity phase transition

It has been conjectured that the phase transition in the Ginzburg-Landau theory is dual to the XY model transition. We study numerically a particular limit of the GL theory where this duality becomes exact, clarifying some of the problems encountered in standard GL theory simulations. This may also explain the failure of the superconductor experiments to observe the XY model scaling.Comment: Lattice2002(higgssusy), 3 page

Finite size scaling analysis of compact QED

We describe results of a high-statistics finite size scaling analysis of 4d compact U(1) lattice gauge theory with Wilson action at the phase transition point. Using a multicanonical hybrid Monte Carlo algorithm we generate data samples with more than 150 tunneling events between the metastable states of the system, on lattice sizes up to 18^4. We performed a first analysis within the Borgs-Kotecky finite size scaling scheme. As a result, we report evidence for a first-order phase transition with a plaquette energy gap, G=0.02667(20), at a transition coupling, beta_T=1.011128(11).Comment: Lattice 2000 (Topics in Gauge Theories),6 pages, 6 figures, LaTe

Gauge-invariant strings in the 3d U(1)+Higgs theory

We describe how the strings, which are classical solutions of the continuum three-dimensional U(1)+Higgs theory, can be studied on the lattice. The effect of an external magnetic field is also discussed and the first results on the string free energy are presented. It is shown that the string free energy can be used as an order parameter when the scalar self-coupling is large and the transition is continuous.Comment: LATTICE98(higgs); missing author added, no changes to tex

Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation

Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase. We investigated the role of leukocytes in the pathogenesis of DIC in OLT by measuring the leukocytic mediators released upon activation (cathepsin B, elastase, TNF, neopterin) and the levels of thrombin-antithrombin III (TAT) complexes, seen as markers of prothrombin activation. Arterial blood samples were taken at 10 different time points during and after OLT. Samples were also taken of the perfusate released from the liver graft vein during the flushing procedure before the reperfusion phase. Aprotinin was given as a continuous infusion (0.2-0.4 Mill. KlU/hr) and its plasma levels were determined. Significantly elevated levels of neopterin (15-fold; P<0.01), cathepsin B (440-fold; P<0.01) in the perfusate, as compared with the systemic circulation, as well as their significant increases in the early reperfusion phase suggested that they were released by the graft liver. This was paralleled by elevated levels of elastase (1.3-fold, P<0.05), TNF (1.5-fold, P=NS), and TAT complexes (1.4-fold; P<0.1) in the perfusate. Significant correlations could be identified between the parameters of leukocyte activation and TAT complexes, whereas no correlation was observed between any of the parameters investigated and the aprotinin levels. Our results strongly indicate a release of leukocytic mediators from the graft liver during its reperfusion which seems to be related to the parallely increased prothrombin activation. No correlation could be seen between levels of aprotinin and levels of leukocytic mediators

Different aprotinin applications influencing hemostatic chances in orthotopic liver transplantation

The effect of different aprotinin applications on hemmtatic changes and blood product requirements in orthotopic liver transplantation was investigated in a prospective, open, and randomized study. From November 1989 to June 1990, 13 patients received aprotinin as a bolus of 0.5 Mill, kallikrein inac-tivator units (KIU) on three occasions in the course of an OLT, whereas 10 other patients were treated with continuous aprotinin infusion of 0.1-0.4 Mill. KIU/hr. Before and after reperfusion of the graft liver, signs of hyperfibrinolysis, measured by thrombelastography, were significantly lower in the infusion group. Tissue-type plasminogen activator (t-PA) activity increased during the anhepatic phase but to a significantly lesser extent in the infusion group. Blood product requirements during OLT were tendentiously higher in the bolus group but not significantly so. However, the use of packed red blood cells was significantly lower in the postoperative period, whereas there was no significant difference in fresh frozen plasma requirements between the two groups. All 23 patients have survived, and only one woman of each group required retransplantation due to severe host-versus-graft reactions. Furthermore, we investigated the perfusate of the graft liver in both groups and detected signs of a decreased t-PA release in the infusion group. Our results demonstrate an advantage of aprotinin given as continuous infusion over bolus application in OLT

Kongenitale Nävi im Kindesalter

Zusammenfassung: Nävi stellen kongenitale hamartomatöse Fehlbildungen unterschiedlicher Bestandteile der Haut dar. Am häufigsten treten kongenitale melanozytäre Nävi (CMN) auf, gefolgt von Nävi epithelialen Ursprungs (epidermale und organoide Nävi). Insbesondere große CMN können zu schwerwiegenden Komplikationen führen, und das Management der Betroffenen stellt ab Geburt eine Herausforderung dar. Entgegen früheren Annahmen ist das Risiko einer malignen Entartung von CMN insgesamt als eher gering anzusehen, steigt jedoch in speziellen Situationen relevant an. Nicht zu vernachlässigen sind mögliche extrakutane Symptome im Falle einer ZNS-Beteiligung, und frühe bildgebende Untersuchungen gehören heute zur Routinediagnostik. Chirurgische Maßnahmen haben noch immer einen hohen Stellenwert in der Behandlung von CMN, die Indikation dazu ist jedoch von Fall zu Fall individuell abzuwägen. Nicht zuletzt leiden die Patienten häufig stark an der ästhetischen Beeinträchtigung durch ihr Muttermal, sodass in der Behandlung auch diesem Punkt Rechnung getragen werden muss. Der Naevus sebaceus ist der häufigste Vertreter der epithelialen Nävi. In 2-13% treten darin Zusatztumoren auf, und eine frühe chirurgische Exzision ist in den meisten Fällen nicht zuletzt auch aus ästhetischen Überlegungen sinnvoll. Epidermale Nävi erfordern bei generalisierter Ausdehnung Zusatzuntersuchungen zum Ausschluss von assoziierten ophthalmologischen, kardialen oder neurologischen Fehlbildunge

Classical and Quantum Annealing in the Median of Three Satisfiability

We determine the classical and quantum complexities of a specific ensemble of three-satisfiability problems with a unique satisfying assignment for up to N=100 and N=80 variables, respectively. In the classical limit we employ generalized ensemble techniques and measure the time that a Markovian Monte Carlo process spends in searching classical ground states. In the quantum limit we determine the maximum finite correlation length along a quantum adiabatic trajectory determined by the linear sweep of the adiabatic control parameter in the Hamiltonian composed of the problem Hamiltonian and the constant transverse field Hamiltonian. In the median of our ensemble both complexities diverge exponentially with the number of variables. Hence, standard, conventional adiabatic quantum computation fails to reduce the computational complexity to polynomial. Moreover, the growth-rate constant in the quantum limit is 3.8 times as large as the one in the classical limit, making classical fluctuations more beneficial than quantum fluctuations in ground-state searches