12 research outputs found
Heavy Oil Laminar Flow in Corrugated Ducts: A Numerical Study Using the Galerkin-Based Integral Method
No full textFluid flow in pipes plays an important role in different areas of academia and industry. Due to the importance of this kind of flow, several studies have involved circular cylindrical pipes. This paper aims to study fully developed internal laminar flow through a corrugated cylindrical duct, using the Galerkin-based integral method. As an application, we present a study using heavy oil with a relative density of 0.9648 (14.6 °API) and temperature-dependent viscosities ranging from 1715 to 13000 cP. Results for different fluid dynamics parameters, such as the Fanning friction factor, Reynolds number, shear stress, and pressure gradient, are presented and analyzed based on the corrugation number established for each section and aspect ratio of the pipe
Unravelling the genetic variability of host resilience to endo- and ectoparasites in Nellore commercial herds
No full textAbstract Background Host resilience (HR) to parasites can affect the performance of animals. Therefore, the aim of this study was to present a detailed investigation of the genetic mechanisms of HR to ticks (TICK), gastrointestinal nematodes (GIN), and Eimeria spp. (EIM) in Nellore cattle that were raised under natural infestation and a prophylactic parasite control strategy. In our study, HR was defined as the slope coefficient of body weight (BW) when TICK, GIN, and EIM burdens were used as environmental gradients in random regression models. In total, 1712 animals were evaluated at five measurement events (ME) at an average age of 331, 385, 443, 498, and 555 days, which generated 7307 body weight (BW) records. Of the 1712 animals, 1075 genotyped animals were used in genome-wide association studies to identify genomic regions associated with HR. Results Posterior means of the heritability estimates for BW ranged from 0.09 to 0.54 across parasites and ME. The single nucleotide polymorphism (SNP)-derived heritability for BW at each ME ranged from a low (0.09 at ME.331) to a moderate value (0.23 at ME.555). Those estimates show that genetic progress can be achieved for BW through selection. Both genetic and genomic associations between BW and HR to TICK, GIN, and EIM confirmed that parasite infestation impacted the performance of animals. Selection for BW under an environment with a controlled parasite burden is an alternative to improve both, BW and HR. There was no impact of age of measurement on the estimates of genetic variance for HR. Five quantitative trait loci (QTL) were associated with HR to EIM but none with HR to TICK and to GIN. These QTL contain genes that were previously shown to be associated with the production of antibody modulators and chemokines that are released in the intestinal epithelium. Conclusions Selection for BW under natural infestation and controlled parasite burden, via prophylactic parasite control, contributes to the identification of animals that are resilient to nematodes and Eimeria ssp. Although we verified that sufficient genetic variation existed for HR, we did not find any genes associated with mechanisms that could justify the expression of HR to TICK and GIN
The Isopropyl Gallate Counteracts Cyclophosphamide-Induced Hemorrhagic Cystitis in Mice
No full textHemorrhagic cystitis is the main adverse effect associated with the clinical use of oxazaphosphorine, resulting in increased oxidative stress and proinflammatory cytokines, which culminate in injury of the bladder tissue. The aim of this study was to evaluate the protective effect of isopropyl gallate (IPG) against ifosfamide (IFOS)-induced hemorrhagic cystitis in mice. The induction of the hemorrhagic cystitis model was carried out using a single dose of IFOS (400 mg/kg, i.p.) four hours after oral pretreatment with IPG (6.25, 12.5, 25, and 50 mg/kg) or saline (vehicle). Mesna (positive control; 80 mg/kg, i.p.) was administered four hours before and eight hours after induction of cystitis. In the present study, IPG 25 mg/kg significantly decreased edema and hemorrhage, with a reduction of the bladder wet weight (36.86%), hemoglobin content (54.55%), and peritoneal vascular permeability (42.94%) in urinary bladders of mice. Interestingly, IPG increased SOD activity (89.27%) and reduced MDA levels (35.53%), as well as displayed anti-inflammatory activity by decreasing TNF-α (88.77%), IL-1β (62.87%), and C-reactive protein (56.41%) levels. Our findings demonstrate that IPG has a substantial protective role against IFOS-induced hemorrhagic cystitis in mice by enhancing antioxidant activity and proinflammatory mechanisms. Thus, IPG represents a promising co-adjuvant agent in oxazaphosphorine-based chemotherapy treatments
Ano VIII, número 15
No full textEspaço e Economia: Revista Brasileira de Geografia Econômica dedica sua 15.ª edição à publicização da segunda parte dos artigos apresentados no III Colóquio Espaço e Economia: Transformações no capitalismo mundial e a produção social do espaço: novos arranjos territoriais e a economia política do desenvolvimento, realizado na Universidade do Estado do Rio de Janeiro, entre os dias 10 e 12 de junho de 2019
Erosividade da chuva e erodibilidade de Cambissolo e Latossolo na região de Lavras, sul de Minas Gerais Rainfall erosivity and erodibility of Cambisol (Inceptisol) and Latosol (Oxisol) in the region of Lavras, Southern Minas Gerais State, Brazil
No full textNo Brasil, ainda são relativamente poucos os estudos envolvendo erodibilidade do solo, principalmente Cambissolos, dada a morosidade na obtenção dos resultados de experimentos com chuva natural. O conhecimento dos índices de erosividade e de erodibilidade é importante para o planejamento conservacionista, contribuindo para a sustentabilidade dos solos. Este estudo teve como objetivos determinar a erosividade da chuva e a erodibilidade de Cambissolo Háplico Tb distrófico típico e Latossolo Vermelho distroférrico típico, sob chuva natural, em Lavras (MG), no período de 1998 a 2002. Os dados de precipitação pluviométrica foram obtidos na Estação Climatológica Principal de Lavras, localizada no campus da Universidade Federal de Lavras, próxima das unidades experimentais de perdas de solo. A erosividade (EI30) foi determinada a partir do produto da energia cinética da chuva pela sua intensidade máxima em 30 min. Estes dados, correlacionados com as perdas de solo, permitiram obter o índice de erodibilidade dos solos. A precipitação total média anual foi 1.287 mm e a erosividade média foi de 4.865 MJ mm ha-1 h-1 ano-1. A erodibilidade foi 0,0355 Mg h MJ-1 mm-1 para o Cambissolo e 0,0032 Mg h MJ-1 mm-1 para o Latossolo, em consonância com seus atributos mineralógicos, químicos, físicos e morfológicos diferenciais.<br>Relatively few studies in Brazil have investigated soil erodibility, mainly for Cambisols (Inceptisols), due to the tediousness of data collection in natural rainfall experiments. Knowledge about erodibility and erosivity is important for conservation planning, which contributes to soil sustainability. This study aimed at evaluating the rainfall erosivity and erodibility of a typic dystrophic Tb Haplic Cambisol (Inceptisol) and a typic dystroferric Red Latosol (Oxisol) under natural rainfall, in Lavras, state of Minas Gerais, Brazil, between 1998 and 2002. Pluvial precipitation data were obtained from the main weather station of Lavras, of the Universidade Federal de Lavras, close to the soil loss experimental plots. Erosivity (EI30) was calculated as the product of the rain kinetic energy by the maximum intensity in 30 min. Based on these data, correlated with the soil losses, the soil erodibility could be computed. The mean annual total precipitation was 1,287 mm and the mean calculated erosivity 4,865 MJ mm ha-1 h-1 year-1. The erodibility of the Cambisol was 0.026 Mg h MJ-1 mm-1 and of the Latosol 0.004 Mg h MJ-1 mm-1, in agreement with their differential mineralogical, chemical, physical and morphological properties
Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest
No full textEquidad en salud
No full text•Acceso a diagnóstico y tratamiento para depresión según posición social en países seleccionados de Latinoamérica •Análisis narrativo de experiencias de chilenos exiliados políticos con discapacidad física en Malmö, Suecia •Caracterización y comparación de puérperas peruanas y chilenas atendidas en el Hospital San José •Conocimientos y prácticas de estudiantes de 7º y 8º básico, de ambos sexos, de Curacaví •Desarrollo económico y mortalidad prematura, Chile, 1994-2003 •Determinación nacional del Índice Significante de Caries (SIC) en adolescentes de 12 años, Chile 2010 •Diagnóstico de salud bucal en niños 2 y 4 años asistentes a la educación preescolar, zonas norte y centro •El GES promueve la equidad en el tratamiento del gran quemado de la tercera edad •Evaluación del nivel de conocimiento en salud bucal de la comunidad educativa preescolar •Factores psicosociales y culturales que inciden en embarazo adolescente en niñas menores de 15 años •Índice Significante de Caries en niños de 6 años, Chile 2010 •La mortalidad por cáncer del cuello uterino en Río de Janeiro: Estudio ecológico •Nivel de desarrollo psicomotor y su relación con el score de riesgo DSM •Perfil en interconsultas dermatológicas del consultorio Padre Esteban Gumucio Vives de Santiago de Chile, 2010 •Prevalencia caries, pérdida de dientes, necesidad de tratamiento en adultos mapuche - huilliches de Isla Huapi •Recursos humanos odontológicos para tratamiento de caries en adolescentes de 12 años, Chile 2010 •Retraso del diagnóstico de tuberculosis en la percepción de los representantes de ONG en Río de Janeiro •Rol de la escuela en promoción de salud y reducción de vulnerabilidad social en salud •Tendencia de las tasas de mortalidad fetal e infantil y sus componentes, Chile 1996- 2006 •Implementación de un mamógrafo móvil para la Región de los Río
Equidad en salud
Get PDF•Acceso a diagnóstico y tratamiento para depresión según posición social en países seleccionados de Latinoamérica •Análisis narrativo de experiencias de chilenos exiliados políticos con discapacidad física en Malmö, Suecia •Caracterización y comparación de puérperas peruanas y chilenas atendidas en el Hospital San José •Conocimientos y prácticas de estudiantes de 7º y 8º básico, de ambos sexos, de Curacaví •Desarrollo económico y mortalidad prematura, Chile, 1994-2003 •Determinación nacional del Índice Significante de Caries (SIC) en adolescentes de 12 años, Chile 2010 •Diagnóstico de salud bucal en niños 2 y 4 años asistentes a la educación preescolar, zonas norte y centro •El GES promueve la equidad en el tratamiento del gran quemado de la tercera edad •Evaluación del nivel de conocimiento en salud bucal de la comunidad educativa preescolar •Factores psicosociales y culturales que inciden en embarazo adolescente en niñas menores de 15 años •Índice Significante de Caries en niños de 6 años, Chile 2010 •La mortalidad por cáncer del cuello uterino en Río de Janeiro: Estudio ecológico •Nivel de desarrollo psicomotor y su relación con el score de riesgo DSM •Perfil en interconsultas dermatológicas del consultorio Padre Esteban Gumucio Vives de Santiago de Chile, 2010 •Prevalencia caries, pérdida de dientes, necesidad de tratamiento en adultos mapuche - huilliches de Isla Huapi •Recursos humanos odontológicos para tratamiento de caries en adolescentes de 12 años, Chile 2010 •Retraso del diagnóstico de tuberculosis en la percepción de los representantes de ONG en Río de Janeiro •Rol de la escuela en promoción de salud y reducción de vulnerabilidad social en salud •Tendencia de las tasas de mortalidad fetal e infantil y sus componentes, Chile 1996- 2006 •Implementación de un mamógrafo móvil para la Región de los Río
Núcleos de Ensino da Unesp: artigos 2012: volume 2: metodologias de ensino e a apropriação de conhecimento pelos alunos
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