The Be X-ray Binary Outburst Zoo

Be X-ray binaries are among the best known transient high-energy sources. Their outbursts are commonly classified into a simple scheme of 'normal' and 'giant' outbursts, but a closer look shows that actual outbursts do not always follow this simple scheme. Recent data show a variety of properties, like pre-flares, shifts of the outburst peaks with respect to the periastron, multi-peaked outbursts etc. We present results from a systematic study of a large number of outbursts monitored by various space missions, comparing outburst properties and their relation to system parameters and current theoretical understanding.Comment: Proceedings of "An INTEGRAL view of the high-energy sky (the first 10 years)" the 9th INTEGRAL Workshop, October 15-19, 2012, Paris, France, in Proceedings of Science (INTEGRAL 2012), Eds. A. Goldwurm, F. Lebrun and C. Winkler, (http://pos.sissa.it/cgi-bin/reader/conf.cgi?confid=176), id PoS(INTEGRAL 2012)01

Multiwavelength study of accretion-powered pulsars

My PhD thesis consists in a multi-frequency approach to High Mass X-ray Binaries (HMXBs), using infrared and X-ray data. On one side, my research project aimed at the identification and characterization of IR counterparts to obscured HMXBs in the Scutum and Norma inner galactic arms. The identification of optical/IR counterparts to HMXBs is a necessary step to undertake detailed studies of these systems. With data limited to the high-energy range, the understanding of their complex structure and dynamics cannot be complete. In the last years, INTEGRAL has revealed the presence of an important population of heavily absorbed HMXBs in the Scutum and Norma regions, virtually unobservable below 4 keV. Optical counterparts to these obscured sources are hardly observable, due to the high interstellar extinction. I selected candidate counterparts by means of a photometric search for emission-line stars in the error boxes of the X-ray sources detected by INTEGRAL. With this objective, I built up (Brγ-K)-(H-K) and (HeI-K)-(H-K) IR color-color diagrams, in which emission-line stars are expected to show up below the absorption-line stars sequence. I applied this technique to search for counterparts to Be/XRBs, whose transient nature prevents the counterpart identification with follow-up X-ray observations with high spatial resolution. For each field, one to four candidate counterparts were identified. I also took spectra of proposed counterparts. The confirmation and spectral classifications of the systems led to unveil the nature of nine INTEGRAL objects. On the other hand, the work intended to provide for the first time a systematic study of four Be/XRBs during giant (type II) outbursts. I employed RXTE data, applying the three techniques of color-color/hardness-intensity diagrams (CD/HID), spectral fitting and Fourier power-spectral analysis, simultaneously, and using the retrieved results and correlations to try to define and characterize spectral states for this class of systems. In this way I followed both a model-independent (CD/HID) and model-dependent approach (spectral fits) to investigate the rapid aperiodic variability as a function of spectral sates in HMXBs. I obtained lightcurves, energy and power spectra for a total number of 320 observations. From X-ray colors, spectral and timing fitting, I clearly identified in all the four systems two different spectral states, i.e. the Diagonal Branch (DB) and Horizontal Branch (HB). The HB corresponds to a lower-flux state, with larger rms than the DB. Also, the power-law photon index decreases with flux in the HB, while stays constant or increases in the DB. The HB shows lower characteristic frequencies of the noise components than in the DB. The cyclotron resonant scattering features are generally associated with the DB, while absent or weaker during the DB. We showed how the transition between the two states may correspond to the transition from the standing shock emission to the thermal mound emission due to the turning point from super-Eddington luminosity regime (DB) to sub-Eddington luminosity regime (HB). From color, spectral and timing point of view, differences among systems easily distinguishes two subgroups, with the slower pulsars, KS 1947+300 and EXO2030+375, on one side, and the faster ones, 4U 0115+63 and V 0332+53, on the other. The first group is characterized by softer spectra in the HB compared with the other systems. Hysteresis is not observed in the slower pulsars, while it is evident in V 0332+53 and 4U 0115+63. Cyclotron resonant scattering features are crucial in the spectral shape of V 0332+53 and 4U 0115+63, where also a harmonic is observed in the 3-30 keV energy range. They are instead absent or very weak in the first group. According to timing features, a strong difference between the two groups is the presence of QPOs in the faster pulsars.El trabajo de tesis consiste en un estudio multifrecuencia de Binarias de rayos X de Alta Masa (HMXBs), utilizando datos infrarrojos y en banda X. E n l o s úl t i m o s a ñ o s l a m i s i ó n I N T E G R A L d e l a A g e n c i a E s p a c i a l E u r o p e a h a r e v e l a d o l a p r e s e n c i a d e u n a i m p o r t a n t e p o b l a c i ó n d e H M X Bs e n l o s b r a z o s g a l ác t i c o s d e S c u t u m y N o r m a . E n e f e c t o , l a m a y o r í a d e l a s n u e v a s H M X Bs d e s c u b i e r t a s p o r INTEGRAL e s t án f u e r t e m e n t e a b s o r b i d a s , v i r t u a l m e n t e i n o b s e r v a b l e s a e n e r g ía s i n f e r i o r e s a l o s 4 k e V . E s o e x p l i c a c o m o n o f u e r o n d e t e c t a d a s p o r l a s m i s i o n e s d e r a y o s X a n t e r i o r e s a I N T E G R A L . L a s c o n t r a p a r t i d a s ó p t i c a s d e e s t a s f u e n t e s o s c u r e c i d a s s o n d i f í c i l m e n t e o b s e r v a b l e s a c a u s a d e l a e l e v a d a e x t i n c i ó n i n t e r e s t e l a r. Por un lado, el objetivo de este proyecto fue la i d e n t i f i c a c i ó n d e c o n t r a p a r t i d a s i n f r a r r o j a s a l a s f u e n t e s d e r a y o s g a m m a d e s c u b i e r t a s p o r I N T E G R A L . La identificación se llevó a cabo a partir de fotometría en las bandas H, K, Br y HeI, y espectroscopía de resolución intermedia en la banda K. Para cada campo de INTEGRAL analizado se identificaron de una a cuatro posibles contrapartidas; nueve objetos desconocidos fueron clasificados como HMXBs. Por otro lado, se llevó a cabo el primer estudio sistemático de cuatro HMXBs durante outbursts gigantes, con el objetivo de definir estados espectrales en esta clase de binarias de rayos X. Utilizando datos del satélite RXTE, se extrajeron curvas de luz, espectros de energía y espectros de potencia de 320 observaciones. A través de los tres diferentes tipos de análisis (colores en banda X, ajustes espectrales y temporales), se identificaron en todas las fuentes dos estados espectrales, denominados “Rama Horizontal” (HB) y “Rama Diagonal” (DB). Al mismo tiempo, las diferencias entre las fuentes analizadas permitieron definir dos subgrupos de sistemas, con características espectrales y temporales propias: por una lado los púlsares lentos, y por otro los más rápidos

Be X-ray Binary Outburst Zoo II

We have continued our recently started systematic study of Be X-ray binary (BeXRB) outbursts. Specifically, we are developing a catalogue of outbursts including their basic properties based on nearly all available X-ray all-sky-monitors. These properties are derived by fitting asymmetric Gaussians to the outburst lightcurves. This model describes most of the outbursts covered by our preliminary catalogue well; only 13% of all datasets show more complex outburst shapes. Analyzing the basic properties, we reveal a strong correlation between the outburst length and the reached peak flux. As an example, we discuss possible models describing the observed correlation in EXO 2030+375

Multi-wavelength observations of the 2002 outburst of GX 339-4: two patterns of X-ray-optical/near-infrared behavior

(Abridged) We report on RXTE and optical/near-infrared (nIR) observations of the black hole transient GX 339-4, made over a time span of 8 months in 2002 and covering the initial rise and transition from a hard to a soft spectral state. Two patterns of correlated X-ray-optical/nIR behavior were found. During the hard state the optical/nIR and X-ray fluxes correlated well, with a nIR vs. X-ray flux relation similar to the relation between X-ray and radio fluxes found in previous studies of GX 339-4 and other black hole binaries. As GX 339-4 went through an intermediate state the optical/nIR fluxes decreased rapidly and once it had entered the spectrally soft state, the optical/nIR spectrum was much bluer and the ratio of X-ray to nIR flux was higher by a factor of more than 10 compared to the hard state. In the spectrally soft state nIR-changes preceded those in the X-rays by more than 2 weeks, indicating a disk origin of the nIR. We present SEDs, including radio data, and discuss possible sources for the optical/nIR emission. We conclude that in the hard state this emission probably originates in the optically thin part of a jet and that in none of the X-ray states X-ray reprocessing is the dominant source of optical/nIR emission. Finally, comparing the light curves from the ASM and PCA instruments, we find that the X-ray/nIR delay depends critically on the sensitivity of the X-ray detector, with the delay inferred from the PCA (if present at all) being a factor of 3-6 times shorter than the delay inferred from the ASM; this may be important in interpreting previously reported X-ray-optical/nIR lags.Comment: 13 pages, including 7 figures, accepted for publication in The Astrophysical Journa

Evolving trends in the management of acute appendicitis during COVID-19 waves. The ACIE appy II study

Background: In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods: From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results: A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion: Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide

Acute Delta Hepatitis in Italy spanning three decades (1991–2019): Evidence for the effectiveness of the hepatitis B vaccination campaign

Updated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p < .001). Over the same period, the male/female ratio decreased from 3.8 to 2.1, the proportion of coinfections increased from 55% to 75% (p = .003) and that of HBsAg positive acute hepatitis tested for by IgM anti-HDV linearly decreased from 50.1% to 34.1% (p < .001). People born abroad accounted for 24.6% of cases in 2004-2010 and 32.1% in 2011-2019. In the period 2010-2019, risky sexual behaviour (O.R. 4.2; 95%CI: 1.4-12.8) was the sole independent predictor of acute HDV; conversely intravenous drug use was no longer associated (O.R. 1.25; 95%CI: 0.15-10.22) with this. In conclusion, HBV vaccination was an effective measure to control acute HDV. Intravenous drug use is no longer an efficient mode of HDV spread. Testing for IgM-anti HDV is a grey area requiring alert. Acute HDV in foreigners should be monitored in the years to come

Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

IMPORTANCE Delays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis. OBJECTIVE To evaluate whether the SARS-CoV-2 pandemic was associated with more advanced oncologic stage and change in clinical presentation for patients with colorectal cancer. DESIGN, SETTING, AND PARTICIPANTS This retrospective, multicenter cohort study included all 17 938 adult patients who underwent surgery for colorectal cancer from March 1, 2020, to December 31, 2021 (pandemic period), and from January 1, 2018, to February 29, 2020 (prepandemic period), in 81 participating centers in Italy, including tertiary centers and community hospitals. Follow-up was 30 days from surgery. EXPOSURES Any type of surgical procedure for colorectal cancer, including explorative surgery, palliative procedures, and atypical or segmental resections. MAIN OUTCOMES AND MEASURES The primary outcome was advanced stage of colorectal cancer at diagnosis. Secondary outcomes were distant metastasis, T4 stage, aggressive biology (defined as cancer with at least 1 of the following characteristics: signet ring cells, mucinous tumor, budding, lymphovascular invasion, perineural invasion, and lymphangitis), stenotic lesion, emergency surgery, and palliative surgery. The independent association between the pandemic period and the outcomes was assessed using multivariate random-effects logistic regression, with hospital as the cluster variable. RESULTS A total of 17 938 patients (10 007 men [55.8%]; mean [SD] age, 70.6 [12.2] years) underwent surgery for colorectal cancer: 7796 (43.5%) during the pandemic period and 10 142 (56.5%) during the prepandemic period. Logistic regression indicated that the pandemic period was significantly associated with an increased rate of advanced-stage colorectal cancer (odds ratio [OR], 1.07; 95%CI, 1.01-1.13; P = .03), aggressive biology (OR, 1.32; 95%CI, 1.15-1.53; P < .001), and stenotic lesions (OR, 1.15; 95%CI, 1.01-1.31; P = .03). CONCLUSIONS AND RELEVANCE This cohort study suggests a significant association between the SARS-CoV-2 pandemic and the risk of a more advanced oncologic stage at diagnosis among patients undergoing surgery for colorectal cancer and might indicate a potential reduction of survival for these patients

In marcia verso il nord

La scheda ripercorre la creazione e i successivi sviluppi del "Grote Trek", la Grande Marcia, mito fondativo dell'ideologia afrikaner dalla fine dell'Ottocento in poi. Il mito viene ripreso e capovolto da diverse scrittrici sudafricane che se ne servono per schierarsi contro il regime di apartheid