373 research outputs found

    Road Rage Menace: A Cross-sectional Study to Assess Driver Anger Level in Public Motor Vehicle Drivers in a City in Central India

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    Introduction: Road rage and aggressive driving is a prevalent condition in today’s society due to motorists’ frustrations during heavy traffic volumes. Objective: This study was done to assess the level of anger amongst the drivers of public transport vehicles in Indore, using Driving Anger Scale (DAS by Deffenbacher et. al.) and various factors affecting it. Material and Methods: A cross-sectional study was conducted among 135 drivers of Public transport vehicle drivers (Star bus, City-van and star cab drivers) in Indore to assess their anger level using Driving Anger Scale. The participants were required to record the amount of anger they would experience in response to each item in the scale (1=not at all angry, 2=a little angry, 3=some anger, 4=much anger, 5=very much angry). Results: The mean DAS score in Indore was found to be 3.013 and in the three organizations namely Star bus drivers, City van drivers and Star cab drivers was 2.92, 3.08 and 3.04 respectively. The DAS score of drivers with respect to the 6 sub-scales were: hostile gestures (Star bus -3.42,City van -3.67,Star cab -3.38), slow driving (Star bus -2.73,City van driv-2.78,Star cab-3.17), traffic obstructions (Star bus-2.85,City van -3.25,Star cab-3.18), discourtesy (Star bus -3.23,City van-3.33,Star cab -3.25)and police presence (Star bus -2.15,City van -1.99,Star cab -2.78), illegal driving (Star bus -3.04,City van -3.14,Star cab -2.89). The DAS scores of the drivers did not vary significantly with age group, experience, and educational qualification. Conclusion: Though DAS scores did not vary between the three groups of drivers, however average level anger for various given circumstances commonly found in the Indian traffic scenario was on the higher side

    Taraxacum officinale and Silybum marianum alone or combined orchestrate experimentally induced hepatic steatosis through lipogenecity, glucose tolerance and oxidant/antioxidant status

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    Natural products with a long history of safety can modulate obesity. Taraxacum officinale, known as (dandelion) and Silybum marianum known as (milk thistle) have garnered attention for their antioxidant and antiobesity activities. The present study was conducted to evaluate the potential role of dandelion and milk thistle alone or combined against high fat diet (HFD) induced steatohepatitis. 60 male albino rats which were equally subdivided into four groups: group I was received only HFD, other groups (II, III, IV) were received dandelion, milk thistle or dandelion/milk thistle combination respectively for 8 weeks alongside HFD. Insulin resistance, glucose tolerance, lipogenesis and antioxidant capacity were evaluated in the liver tissue. HFD fed rats exhibited increased insulin resistance-related biomarkers, H2O2 level, mRNA expression of sterol regulatory element-binding protein-1c (SREBP-1c) as well as fatty acid synthase (FAS) activity with decreased reduced glutathione (GSH) level. Herbal supplementation improved those results with best results were for dandelion/milk thistle combination group. Results were confirmed with histopathological examination. Both dandelion and milk thistle alone or combined improved glucose tolerance and insulin sensitivity, decreased lipogenesis and increased antioxidant capacity with best results obtained in dandelion/milk thistle combination group, implying a potential application in the treatment of hepatic steatosis associated obesity.© 2015 International Formulae Group. All rights reservedKeywords: High fat diet, obesity, dandelion, milk thistle, lipogenesis, insulin resistanc

    Using Signal Processing in Tandem With Adapted Mixture Models for Classifying Genomic Signals

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    Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in finding the appropriate spectral representation of a biomolecular sequence, especially when multiple variable-length sequences need to be handled consistently. In this study, we address this challenge in the context of the well-studied problem of classifying genomic sequences into different taxonomic units (strain, phyla, order, etc.). We propose a novel technique that employs signal processing in tandem with Gaussian mixture models to improve the spectral representation of a sequence and subsequently the taxonomic classification accuracies. The sequences are first transformed into spectra, and projected to a subspace, where sequences belonging to different taxons are better distinguishable. Our method outperforms a similar state-of-the-art method on established benchmark datasets by an absolute margin of 6.06% accuracy

    Electronic structure of carbon-free silicon oxynitride films grown using an organic precursor hexamethyl-disilazane

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    Silicon oxynitride films are grown by plasma-enhanced chemical vapour deposition on single-crystal Si(100) and textured Si solar cells, using a safe organic precursor, hexamethyl-disilazane. Using the Lucovsky-Phillips criterion of bond coordination constraints, we grow high-quality thin (~20 Å) and thick (up to 2700 Å) films which are carbon free (<1.0{%}) as characterized by x-ray photoemission spectroscopy (XPS) and Auger electron spectroscopy depth profiles. Core-level and valence band XPS is used to conclusively identify oxynitride bonding and band gap reduction in SiOxNy. For a λ/4 'blue' anti-reflection coating on the solar cells with uniform thickness (870± 15 Å) and composition (SiO1.6± 0.1N0.3± 0.05), an efficiency (AM 1) increase of 1{%} is obtained

    Wheat Germ Oil Restores Testicular Function Through Modulation of Oxidative Stress in Male Adult Rats Exposed to Chromium VI

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    This research was outlined to assess the protective and therapeutic role of wheat germ oil against chromium VI -induced oxidative stress and testicular dysfunction in male adult rats through evaluation of semen picture, measuring the sex hormone levels, oxidative stress markers, DNA fragmentation percentage and histopathological changes in the testes. Twenty-eight adult Wister male rats were assigned into four equal groups: Group 1; Control, group 2; Cr VI, group 3; Cr VI + WGO, and group 4; WGO. WGO showed a significant increment in the RBC, Hb, Ht, WBC and Plts. WGO restored the levels of testicular antioxidant enzymes, NO, MDA as well as GSH. Also, WGO in-combination with Cr VI showed a significant (p<0.05) increase in the levels of testosterone, LH, GnRH hormones and 17β-HSD enzyme, while, FSH was decreased. Data showed that treatment of male rats with WGO and Cr VI caused an increase in sperm count, motility, and decrease in sperm abnormality. Combination of WGO with Cr VI revealed a decrease in the levels of TL, TC, TG and LDL–C, while, HDL–C was increased. Rats administrated with WGO in-combination with Cr VI exhibited a slight improvement in testicular DNA integration compared to Cr VI-treated group. Further, co-administration of WGO + Cr VI revealed a slight improvement in the pathological alterations; the cellular layers of the seminiferous tubules more or less near to the normal structure. It was concluded that wheat germ oil can be an effective antioxidant in modulating Cr VI-induced male infertility, and may lead to improve the male reproductive performance

    Coronavirus Disease 2019: Knowledge, Attitude, Practice, and Perceived Barriers among Health care Workers at Cairo University Children Hospital, Egypt

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    BACKGROUND: Insufficient knowledge and negative attitude toward coronavirus disease 2019 (COVID-19) among health care workers (HCWs) could lead to faulty practices resulting in delayed diagnosis and spread of the disease. AIM: this study was conducted to assess the knowledge, attitude, practice, and perceived barriers to infection control toward COVID-19 among Egyptian HCWs. METHODS: A cross-sectional study was conducted in Cairo University Children Hospital, with 537 HCWs (doctors and nurses) enrolled. RESULTS: HCWs had an overall good knowledge level about COVID-19 where 61% had a knowledge score of ≥18 points (out of 23). Doctors were more knowledgeable than nurses. About 64% of HCWs were considered as having positive attitude (scored ≥10 out of 13 points), with a significantly higher positive attitude among nurses. The mean practice score of HCWs was 1.0 ± 2.0 with a significantly higher good practice among nurses. Younger age, being a doctor, and higher qualification were the significant positive predictors of acquiring knowledge about the disease. The most commonly perceived barriers for applying infection control measures in hospitals were overcrowdings in health-care facilities (78.2%) and insufficient infection control policies (62.6%). CONCLUSION: HCWs in general expressed good knowledge, positive attitude, and good practice toward COVID-19 despite some gaps that were detected in specific items. Proper planning of educational programs that are directed according to the needs of different groups of HCWs is crucial. Effective policies should be established to overcome the barriers for applying infection control in health facilities

    Antibiotic Resistance Bacteria in Tertiary Hospitals in Chittagong, Bangladesh

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    Nosocomial infections (HAI) are major cause for mortality and morbidity worldwide. In low income countries, data suggests 6.5% - 33% of patients have HAI with pneumonia being the most frequent..Antibiotic resistance is highly prevalent in developing countries due to self medication, easy availability and poor regulatory controls. Clinicians have been left with limited antibiotic drug options for the treatment of bacterial infections due to escalated rates of resistance. This comparative study aimed to identify microorganisms from hospital surfaces in two major tertiary care hospitals in Chittagong, Bangladesh. It also identifies antibiotic susceptibility of the samples to antibiotics commonly used in Bangladesh. Samples were collected by swabbing different environmental surface around patients in both hospitals. Identification of bacteria was done by culturing in nutrient media and various common biochemical techniques. Antibiotic sensitivity was determined by disk diffusion method. During the study, 27 samples were collected from different surfaces in different wards of the hospitals. The predominating organisms were Streptococcus, Staphylococcus, Bacillus, Pseudomonas and Serratia. The isolates of organisms showed high level of resistance to commonly used antibiotics especially a fourth generation cephalosporin, cefepime. In addition, antibiotic sensitivity tests showed small colonies or film of growth within zone of inhibition of some of the samples known as “satellite colonies”. The study identified bacterial isolates responsible for HAI in tertiary hospitals and their susceptibility to antibiotics. Further research is currently being conducted on understanding the satellite colonies some of the isolates from hospital surface swabs have exhibited

    Hypolipidemic Effect of Hyphaene thebaica (Doum-palm) in Induced Hypercholestrolemic Wistar Albino Rats

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    Abstract This study is designed to investigate the effect of feeding the whole bulb (mesocarp) of Hyphaene thebaica fruit, as 3% of the diet, on lipid profile in Diet-induced hypercholesterolemic Wistar albino rats. Various dietary rations were prepared by addition of H. thepaica, to assess their impact on the serum triglycerides, total cholesterol and its fractions the LDL-C, HDL-C and VLDL-C in normal and induced hypercholestrolemic rats. The rats were divided into four groups and fed for three-weeks as follows: Group 1 fed basal rat diet, group 2 fed the basal rat diet mixed with H. thebaica, group 3 fed high fat diet (the basal rat diet mixed with, calculated amount of, egg yolk to formulate a diet of 1% cholesterol) and group 4 fed the high fat diet mixed with H. thebaica. By the end of the experiment a significant (P=0.03) increase in serum triglycerides and the VLDL-C was observed in groups (3 and 4) compared to the control group. Also the level of LDL-C increased significantly (P=0.04) in group 3 but decreased numerically in group 4. Moreover, the lowest level of the total cholesterol was recorded in group 2 compared to the other groups. However, feeding H. thebaica when mixed with high fat in the diet, resulted in significantly (P=0.02) decreased HDL-C levels. In conclusion this study suggested that H. thebaica contains active ingredients that can manipulate blood lipids and can protect from an increase of the bad cholesterol in the blood, even if a high fat diet is consumed. The present experiment also showed that, the increase of serum triglycerides and VLDL-C levels due to feeding high fat diet in group 3, was augmented by adding H. thebaica to the diet in group 4, so the study of the fatty acid composition of these lipid fractions is recommended

    Preprocessing signal for Speech Emotion Recognition

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    Abstract: In this paper, we introduce and study preprocessing signal for speech emotion recognition. The aim of our work is to get pure signal which is created by sampling the signal from speaker. The discrimination between speech and music waves was achieved. A good signal is obtained by using preprocessing then it used for feature extraction. The files we used in this paper are wave-type for male, female and music have sample rate 48000, bit resolution is 16-bits and Mono channel. The Berlin dataset and RAVDESS dataset are used in this work
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