The string partition function in Hull's doubled formalism

T-duality is one of the essential elements of string theory. Recently, Hull has developed a formalism where the dimension of the target space is doubled so as to make T-duality manifest. This is then supplemented with a constraint equation that allows the connection to the usual string sigma model. This paper analyses the partition function of the doubled formalism by interpreting the constraint equation as that of a chiral scalar and then using holomorphic factorisation techniques to determine the partition function. We find there is quantum equivalence to the ordinary string once the topological interaction term is included.Comment: 16 pages, latex, v2 typos corrected, v3 some comments adde

A note on the M2-M5 brane system and fuzzy spheres

This note covers various aspects of recent attempts to describe membranes ending on fivebranes using fuzzy geometry. In particular, we examine the Basu-Harvey equation and its relation to the Nahm equation as well as the consequences of using a non-associative algebra for the fuzzy three-sphere. This produces the tantalising result that the fuzzy funnel solution corresponding to Q coincident membranes ending on a five-brane has $Q^{3/2}$ degrees of freedom.Comment: 17 pages, late

Five-brane Calibrations and Fuzzy Funnels

We present a generalisation of the Basu-Harvey equation that describes membranes ending on intersecting five-brane configurations corresponding to various calibrated geometries.Comment: 20 pages, latex, v2: typos fixed and refs adde

Background Field Equations for the Duality Symmetric String

This paper describes the background field equations for strings in T-duality symmetric formalisms in which the dimension of target space is doubled and the sigma model supplemented with constraints. These are calculated by demanding the vanishing of the beta-functional of the sigma model couplings in the doubled target space. We demonstrate the equivalence with the background field equations of the standard string sigma model.Comment: 26 pages, latex, v2 typos correcte

A Double Sigma Model for Double Field Theory

We define a sigma model with doubled target space and calculate its background field equations. These coincide with generalised metric equation of motion of double field theory, thus the double field theory is the effective field theory for the sigma model.Comment: 26 pages, v1: 37 pages, v2: references added, v3: updated to match published version - background and detail of calculations substantially condensed, motivation expanded, refs added, results unchange

Connecting T-duality invariant theories

We show that the vanishing of the one-loop beta-functional of the doubled formalism (which describes string theory on a torus fibration in which the fibres are doubled) is the same as the equation of motion of the recently proposed generalised metric formulation of double field theory restricted to this background: both are the vanishing of a generalised Ricci tensor. That this tensor arises in both backgrounds indicates the importance of a new doubled differential geometry for understanding both constructions.Comment: 25 pages. v2: published version with minor correction

Superconformal Yang-Mills quantum mechanics and Calogero model with OSp(N|2,R) symmetry

In spacetime dimension two, pure Yang-Mills possesses no physical degrees of freedom, and consequently it admits a supersymmetric extension to couple to an arbitrary number, N say, of Majorana-Weyl gauginos. This results in (N,0) super Yang-Mills. Further, its dimensional reduction to mechanics doubles the number of supersymmetries, from N to N+N, to include conformal supercharges, and leads to a superconformal Yang-Mills quantum mechanics with symmetry group OSp(N|2,R). We comment on its connection to AdS_2 \times S^{N-1} and reduction to a supersymmetric Calogero model.Comment: 1+28 pages, no figure; Refs added. To appear in JHE

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN