90 research outputs found

    Some Effects of Cover over Coniferous Seedbeds in Southern New England

    Get PDF
    The object of the study as at first conceived was to secure experimental data under the climatic conditions of southern Connecticut: 1. On the effect of shade as compared with full light on the time required for germination, and on germination values in representative conifers, and on survival and growth during the first season. 2. On the effect of mulch as compared with exposed soil on the time required for germination, and on germination values in representative conifers, and on survival and growth during the first season

    Performance of the ADAPT-Treated CardioCel® Scaffold in pediatric patients with congenital cardiac anomalies: Medium to Long-Term outcomes

    Get PDF
    Background: A Phase II Clinical Trial reviewed the performance (morbidity and calcification) of the tissue-engineered ADAPT® bovine pericardial scaffold (CardioCel®) in pediatric patients (n = 30) with congenital cardiac defects. In that study, CardioCel® demonstrated no graft-related morbidity and mortality in 25 patients, over 12 months. Five patients died due to non-graft-related events. Echocardiography revealed hemodynamically stable repairs with no calcification of the scaffold. Magnetic resonance imaging (MRI) at 12 months in 10 patients confirmed the absence of calcification. These patients were followed up for further up to 10 years. We present the results of this retrospective review of these patients that were followed for further medium to long-term (median 7.2 years, 25%: 3.6 years 75%: 9.25 years) postoperatively in these patients. Methods: Between April 2008 and September 2009, CardioCel® was implanted in 30 patients with congenital cardiac defects. Efficacy measures included graft-related mortality, morbidity and haemodynamic abnormalities. Calcification was assessed by standard 2D-M mode echocardiography and MRI at 12 months. Medium to long-term assessment included routine clinical assessments and echocardiography. Results: Median age at surgery was 18 months (27 days−13 years). Twenty-five patients (142 patient years) were followed for up to 10 years. The 10-year survival rate is estimated as 86.9% (95% CI 71.4–100.0%) over the entire follow-up period. One patient was lost to follow-up. No graft-related mortality was encountered up to a median follow-up of 7.2 years. Two patients died (pacemaker complications >5 years and arrhythmia >7 years postoperatively). No graft failure, thromboembolic events, infections or device-related reinterventions were recorded. Non-significant residual leaks occurred in 3 patients. Echocardiography demonstrated the absence of calcification in all implants. Conclusion: The tissue-engineered ADAPT® bovine pericardial scaffold demonstrated excellent medium to long-term performance (up to 10 years) when used as a scaffold for repair of congenital cardiac defects in children. Durability, acellularity, biostability and non-calcifying potential of CardioCel® makes it a very attractive tissue for congenital cardiac repair procedures

    Persistent pain following ankle sprain: Bilateral accessory soleus muscles

    Get PDF
    Persistent pain following ankle sprain remains a difficult diagnostic and management dilemma. We report a 22 year old rugby player who presented with a persistent painful left ankle following a minor ankle sprain. After examination and imaging investigations, a symptomatic accessory soleus muscle was diagnosed on the left ankle, and an asymptomatic accessory soleus muscle on the right

    Phage Encoded H-NS: A Potential Achilles Heel in the Bacterial Defence System

    Get PDF
    The relationship between phage and their microbial hosts is difficult to elucidate in complex natural ecosystems. Engineered systems performing enhanced biological phosphorus removal (EBPR), offer stable, lower complexity communities for studying phage-host interactions. Here, metagenomic data from an EBPR reactor dominated by Candidatus Accumulibacter phosphatis (CAP), led to the recovery of three complete and six partial phage genomes. Heat-stable nucleoid structuring (H-NS) protein, a global transcriptional repressor in bacteria, was identified in one of the complete phage genomes (EPV1), and was most similar to a homolog in CAP. We infer that EPV1 is a CAP-specific phage and has the potential to repress up to 6% of host genes based on the presence of putative H-NS binding sites in the CAP genome. These genes include CRISPR associated proteins and a Type III restriction-modification system, which are key host defense mechanisms against phage infection. Further, EPV1 was the only member of the phage community found in an EBPR microbial metagenome collected seven months prior. We propose that EPV1 laterally acquired H-NS from CAP providing it with a means to reduce bacterial defenses, a selective advantage over other phage in the EBPR system. Phage encoded H-NS could constitute a previously unrecognized weapon in the phage-host arms race

    Identification of stable QTLs for vegetative and reproductive traits in the microvine (Vitis vinifera L.) using the 18 K Infinium chip

    Get PDF
    UMR AGAP - équipe DAAV - Diversité, adaptation et amélioration de la vigne[b]Background[/b] [br/]The increasing temperature associated with climate change impacts grapevine phenology and development with critical effects on grape yield and composition. Plant breeding has the potential to deliver new cultivars with stable yield and quality under warmer climate conditions, but this requires the identification of stable genetic determinants. This study tested the potentialities of the microvine to boost genetics in grapevine. A mapping population of 129 microvines derived from Picovine x Ugni Blanc flb, was genotyped with the Illumina® 18 K SNP (Single Nucleotide Polymorphism) chip. Forty-three vegetative and reproductive traits were phenotyped outdoors over four cropping cycles, and a subset of 22 traits over two cropping cycles in growth rooms with two contrasted temperatures, in order to map stable QTLs (Quantitative Trait Loci). [br/][b]Results[/b] [br/]Ten stable QTLs for berry development and quality or leaf area were identified on the parental maps. A new major QTL explaining up to 44 % of total variance of berry weight was identified on chromosome 7 in Ugni Blanc flb, and co-localized with QTLs for seed number (up to 76 % total variance), major berry acids at green lag phase (up to 35 %), and other yield components (up to 25 %). In addition, a minor QTL for leaf area was found on chromosome 4 of the same parent. In contrast, only minor QTLs for berry acidity and leaf area could be found as moderately stable in Picovine. None of the transporters recently identified as mutated in low acidity apples or Cucurbits were included in the several hundreds of candidate genes underlying the above berry QTLs, which could be reduced to a few dozen candidate genes when a priori pertinent biological functions and organ specific expression were considered. [br/][b]Conclusions[/b] [br/]This study combining the use of microvine and a high throughput genotyping technology was innovative for grapevine genetics. It allowed the identification of 10 stable QTLs, including the first berry acidity QTLs reported so far in a Vitis vinifera intra-specific cross. Robustness of a set of QTLs was assessed with respect to temperature variatio

    A responsibility to protect Africa from the West? South Africa and the NATO intervention in Libya

    Get PDF
    This article will argue that South Africa’s approach to conflict mediation and peace building is informed by the ANC’s experience of the transition to democracy in South Africa and is widely misinterpreted. This was particularly evident in the Libyan crisis, where South Africa was widely accused of exhibiting a morally duplicitous and ideologically rudderless foreign policy because of the manner in which it initially supported intervention and subsequently became one of the fiercest critics of the NATO campaign. It will be argued that this is an inaccurate caricature of South Africa’s foreign policy and that South Africa’s approach could in fact inject vital pluralism into debates about the future of humanitarian interventions in Africa. The article draws upon interviews with senior officials in the ruling African National Congress (ANC) and South African officials who negotiated the UN Security Council resolutions that sanctioned intervention in Libya

    Free charge carrier absorption in silicon at 800 nm

    Get PDF
    CITATION: Heisel, P.-C. et al. 2016. Free charge carrier absorption in silicon at 800 nm. Applied Physics B, 122:60, doi:10.1007/s00340-015-6308-5.The original publication is available at https://www.springer.com/journal/340The transmission of a Ti:sapphire laser beam (c.w. and fs pulsed operation at 800 nm) through a 10-μm-thin oxidized silicon membrane at 45° angle of incidence at first increases with the incident laser power, then shows a maximum, and finally decreases considerably. This nonlinear transmission behavior is the same for c.w. and pulsed laser operation and mainly attributed to free charge carrier absorption (FCA) in Si. A simple FCA model is developed and tested.https://link.springer.com/article/10.1007/s00340-015-6308-5Post-prin
    • …
    corecore