22 research outputs found
Performance Analysis of Multiple Access Techniques for LTE system under Symbol Error Rate (SER) Calculation
In the recent years, so many technologies in multiple access trends have influenced the field of Wireless Sensor Networks in significant ways. Various trends are readily available technology of ubiquitous wireless sensor networks as well as wireless communication networks and progress in the development of two multiple access techniques are compared in this scenario: the OFDMA and SC-FDMA. The OFDMA and SC-FDMA transceivers are modeled and simulated considering both the interleaved and localized subcarriers mapping schemes. WSNs have the potentiality to connect the physical world with the virtual world by forming a network of sensor nodes. To prolong the networklsquo;s hop in terms of single and two hop using both techniques should be used in the sensor nodes. The minimization of computing and storage platforms as well as the development of novel micro sensors and sensor materials with high reliability force encourages technology in research on WSN. In this paper, we will proposed the field of multipath routing in wireless sensor networks, and mainly focus on the technology of SER of WSNs
Literature Survey of Security Enhancement in MANET Routing Protocols of WLANs
A Mobile Ad-hoc Network (MANET) is an autonomous collection of mobile users that communicate over relatively bandwidth constrained wireless links. One of the main issues in such networks is performance- in a dynamically changing topology; the nodes are expected to be power-aware due to the bandwidth constrained network. Another issue in such networks is security - since every node participates in the operation of the network equally, Malicious nodes are difficult to detect. There are several applications of mobile ad hoc networks such as disaster recovery operations, battle field communications, etc. The most active research area under MANET routing protocol is security. MANETs have certain unique characteristics that make them vulnerable to several types of attacks. Since they are deployed an open environment where all nodes co-operate in forwarding the packets in the network, Malicious nodes are difficult to detect
Formulation and Assessment of an Instant Degrading Film of the Poorly Soluble Medicament Cilnidipine
Cilnidipine, also known as dihydropyridine, is a calcium antagonist that has that chemical formula. It does this by blocking L-type calcium channels, which prevents calcium from entering the capillaries. This results in a reduction in blood pressure. When taken orally in tablet form, the medicine has a lower bioavailability than when it is injected. This is because it is less water-soluble. A substance was produced as a result of the combination of PEG 400 and propylene glycol that was neither hard nor sticky in nature. Inclusion complexes that are produced with cyclodextrin contribute to an improvement in the drug\u27s solubility and release. We studied the influence that PEG 400 and propylene glycol would have on the formula by using a factorial arrangement. A 32-full factorial design was utilised in order to attain the maximum level of optimization for the rapidly disintegrating film. In in vitro drug release investigations using PEG 400 and propylene glycol, independent parameters such as pH, thickness, weight uniformity, percent drug content, folding endurance, and disintegration time were examined and analysed
Study of Photoluminescence Behaviour of Porous Silicon Samples Prepared at 20 mA Current Density
The paper presents a study on a series of porous silicon films of various thicknesses, prepared at 20 mA current density using a photoluminescence fitting model to determine the average crystallite size of sphe-rical shaped interconnected silicon quantum dots. Discrepancy in photoluminescence behavior of the samples is well explained with this model.
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Bilateral total knee arthroplasty with modified primary components in the management of neuropathic arthropathy related to chronic pancreatitis: a case with 5-year follow-up
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Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
An Unusual Hernia Complication: A Late Presentation
A 67-year-old man presented with a 10-year history of intermittent right iliac fossa pain. His only significant past medical history was an inguinal hernia repair 10 years ago. After investigations, the patient underwent a laparotomy. He had a localised caecal perforation secondary to a misplaced prolene suture. A right hemicolectomy was performed