Properties of the Young Milky Way Globular Cluster Whiting 1 from Near-Infrared Photometry

Whiting 1 is a member of the fast-growing group of young globular clusters in the Milky Way halo. Preliminary estimates of its fundamental parameters have been provided using optical photometry and low resolution spectroscopy. In an attempt to strengthen our knowledge of Whiting 1, in this study we employ a complementary approach. Isochrone fitting method was applied on the Near-Infrared Color-Magnitude Diagram and yields an age t=5.7$\pm$0.3 Gyr, metallicity $z$=0.006$\pm$0.001 ([Fe/H]=$-$0.5$\pm$0.1) and distance modulus $(m-M)_0$=17.48$\pm$0.10. Our results confirm that Whiting 1 is a young and moderately metal-rich globular cluster. It is one of the youngest from the Sgr dSph. We fitted an Elson, Fall and Freeman (EFF) profile to the near-infrared number counts, and measured cluster core radius $r_c$=9.1${\prime\prime}$$\pm$3.9${\prime\prime}$. Two probable eclipsing variables in the cluster were found from multi-epoch $V$ band photometry. Finally, an unknown galaxy cluster was identified on our $K$ vs. $(J-K)$ color-magnitude diagram. It has a redshift z$\sim$1, and it is located at about 1${\prime}$ from the center of Whiting 1 at $\alpha_{J2000}=02^{h} 02^{m} 56.6^{s}$, $\delta_{J2000}=-03^{\circ} 16{\prime} 09{\prime\prime}$, contaminating the cluster photometry.Comment: Accepted for publication in MNRAS, 6 pages, 8 figure

WFPC2 Observations of Massive and Compact Young Star Clusters in M31

We present color magnitude diagrams of four blue massive and compact star clusters in M31: G38, G44, G94, and G293. The diagrams of the four clusters reveal a well-populated upper main sequence and various numbers of supergiants. The U-B and B-V colors of the upper main sequence stars are used to determine reddening estimates of the different lines of sight in the M31 disk. Reddening values range from E(B-V) = 0.20 +/- 0.10 to 0.31 +/- 0.11. We statistically remove field stars on the basis of completeness, magnitude and color. Isochrone fits to the field-subtracted, reddening-corrected diagrams yield age estimates ranging from 63 +/- 15 Myr to 160 +/- 60 Myr. Implications for the recent evolution of the disk near NGC 206 are discussed.Comment: 17 pages, Latex, ApJ, in Pres

Optical monitoring of the z=4.40 quasar Q 2203+292

We report Cousins R-band monitoring of the high-redshift (z=4.40) radio quiet quasar Q 2203+292 from May 1999 to October 2007. The quasar shows maximum peak-to-peak light curve amplitude of ~0.3 mag during the time of our monitoring, and ~0.9 mag when combined with older literature data. The rms of a fit to the light curve with a constant is 0.08 mag and 0.2 mag, respectively. The detected changes are at ~3-sigma level. The quasar was in a stable state during the recent years and it might have undergone a brightening event in the past. The structure function analysis concluded that the object shows variability properties similar to those of the lower redshift quasars. We set a lower limit to the Q 2203+292 broad line region mass of 0.3-0.4 M_odot. Narrow-band imaging search for redshifted Ly_alpha from other emission line objects at the same redshift shows no emission line objects in the quasar vicinity.Comment: 9 pages, 8 figures, accepted for publication in MNRA

State estimation of a dehydration process by interval analysis

This article presents a general methodology of state estimation by interval analysis in a dynamic system modeled by difference equations. The methodology is applied to a pineapple osmotic dehydration process, in order to predict the behavior of the process within a range of allowed perturbation. The paper presents simulations and validations

Branch-and-lift algorithm for deterministic global optimization in nonlinear optimal control

This paper presents a branch-and-lift algorithm for solving optimal control problems with smooth nonlinear dynamics and potentially nonconvex objective and constraint functionals to guaranteed global optimality. This algorithm features a direct sequential method and builds upon a generic, spatial branch-and-bound algorithm. A new operation, called lifting, is introduced, which refines the control parameterization via a Gram-Schmidt orthogonalization process, while simultaneously eliminating control subregions that are either infeasible or that provably cannot contain any global optima. Conditions are given under which the image of the control parameterization error in the state space contracts exponentially as the parameterization order is increased, thereby making the lifting operation efficient. A computational technique based on ellipsoidal calculus is also developed that satisfies these conditions. The practical applicability of branch-and-lift is illustrated in a numerical example. © 2013 Springer Science+Business Media New York

The January 2015 outburst of a red nova in M 31

© ESO 2015. Context. M31N 2015-01a (or M31LRN 2015) is a red nova that erupted in January 2015 - the first event of this kind observed in M 31 since 1988. Very few similar events have been confirmed as of 2015. Most of them are considered to be products of stellar mergers. Aims. Results of an extensive optical monitoring of the transient in the period January-March 2015 are presented. Methods. Eight optical telescopes were used for imaging. Spectra were obtained on the Large Altazimuth Telescope (BTA), the Gran Telecsopio Canarias (GTC) and the Rozhen 2 m telescope. Results. We present a highly accurate 70 d light curve and astrometry with a 0.05″uncertainty. The colour indices reached a minimum of 2-3 d before peak brightness and rapidly increased afterwards. The spectral type changed from F5I to F0I in 6 d before the maximum and then to K3I in the next 30 d. The luminosity of the transient was estimated to be 8.7-2.2+3.3 × 105 L⊙ during the optical maximum. Conclusions. Both the photometric and the spectroscopic results confirm that the object is a red nova, similar to V838 Monocerotis

Hijacking of the Pleiotropic Cytokine Interferon-γ by the Type III Secretion System of Yersinia pestis

Yersinia pestis, the causative agent of bubonic plague, employs its type III secretion system to inject toxins into target cells, a crucial step in infection establishment. LcrV is an essential component of the T3SS of Yersinia spp, and is able to associate at the tip of the secretion needle and take part in the translocation of anti-host effector proteins into the eukaryotic cell cytoplasm. Upon cell contact, LcrV is also released into the surrounding medium where it has been shown to block the normal inflammatory response, although details of this mechanism have remained elusive. In this work, we reveal a key aspect of the immunomodulatory function of LcrV by showing that it interacts directly and with nanomolar affinity with the inflammatory cytokine IFNγ. In addition, we generate specific IFNγ mutants that show decreased interaction capabilities towards LcrV, enabling us to map the interaction region to two basic C-terminal clusters of IFNγ. Lastly, we show that the LcrV-IFNγ interaction can be disrupted by a number of inhibitors, some of which display nanomolar affinity. This study thus not only identifies novel potential inhibitors that could be developed for the control of Yersinia-induced infection, but also highlights the diversity of the strategies used by Y. pestis to evade the immune system, with the hijacking of pleiotropic cytokines being a long-range mechanism that potentially plays a key role in the severity of plague