Middle School Teachers\u27 Perceptions of Brain-Based Learning and the Implementation of Physical Brain Breaks as a Classroom Management Strategy

The purpose of this study was to better understand educators\u27 perspectives of physical brain breaks at middle schools located in the northwestern part of North Carolina as it relates to the brain-based learning theory. This study is important because it helps to bridge the gap between the educational and neuroscience fields by providing teachers’ perspectives about using physical brain breaks, issues implementing them, and the importance of relationships with educational stakeholders. After submitting the survey, participants were asked to share their contact information to show their willingness to participate in a focus group with their peers to answer 10 questions about their experiences with physical brain breaks or the lack thereof. The data from the survey were analyzed for themes and common responses supplied by the participants. Data from the survey showed a minority of the participants give a physical brain break, while most do not and do not have a desire to learn more about them. Data from the focus group were analyzed by having the recorded conversation transcribed and then looking for repeating words and phrases. Themes such as time, classroom management, and relationships were discovered in the analysis, with the most emphasis on the importance of relationships. The implications of this study include time, space, and the willingness of teachers to implement a strategy for which they have not received professional development for successful implementation

Activity-Based Costing System Required For Successful Customer Relationship Management

The purpose of this paper is to discuss the importance of Activity-Based Costing to successful Customer Relationship Management.  The value a customer adds to a company through customer loyalty, using Customer Profitability Analysis

Pathogenicity to western larch (Larix occidentalis) of two fungi, Ophiostoma oseudotsugae and Leptoaraghium abietinum, associated with the douglas-fir beetle (Coleoptera: Scolytidae) in Eastern Oregon, U.S.A.

Pole-sized, live western larch Larix occidentalis Nutt.) were inoculated with Ophiostoma pseudotsugae(Rumb.) von Arx or Leptographium abietinum (Peck) Wingf., two blue stain fungi associated with the Douglas-fir beetle (Dendroctonous pseudotsugae Hopkins), to assess their pathogenicity. Inoculation with O. pseudotsugae resulted in a significantly greater percentage of necrotic phloem compared to inoculations with L. abietinum. The percentage of occluded sapwood was significantly greater after L. abietinum inoculations compared to O. pseudotsugae inoculations. Percentages of necrotic phloem and occluded sapwood were positively correlated with inoculation density. In the inoculation band, all trees had greater than 60% functional sapwood four months after inoculation. The results suggest that western larch can successfully limit colonization by Q. pseudotsugae and L. abietinum. The inability of the fungi to thrive in live western larch may be a factor in the consistent failure of Douglas-fir beetle brood to survive in live western larch

Stimulant Reduction Intervention using Dosed Exercise (STRIDE) - CTN 0037: Study protocol for a randomized controlled trial

Background: There is a need for novel approaches to the treatment of stimulant abuse and dependence. Clinical data examining the use of exercise as a treatment for the abuse of nicotine, alcohol, and other substances suggest that exercise may be a beneficial treatment for stimulant abuse, with direct effects on decreased use and craving. In addition, exercise has the potential to improve other health domains that may be adversely affected by stimulant use or its treatment, such as sleep disturbance, cognitive function, mood, weight gain, quality of life, and anhedonia, since it has been shown to improve many of these domains in a number of other clinical disorders. Furthermore, neurobiological evidence provides plausible mechanisms by which exercise could positively affect treatment outcomes. The current manuscript presents the rationale, design considerations, and study design of the National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) CTN-0037 Stimulant Reduction Intervention using Dosed Exercise (STRIDE) study. Methods/Design: STRIDE is a multisite randomized clinical trial that compares exercise to health education as potential treatments for stimulant abuse or dependence. This study will evaluate individuals diagnosed with stimulant abuse or dependence who are receiving treatment in a residential setting. Three hundred and thirty eligible and interested participants who provide informed consent will be randomized to one of two treatment arms: Vigorous Intensity High Dose Exercise Augmentation (DEI) or Health Education Intervention Augmentation (HEI). Both groups will receive TAU (i.e., usual care). The treatment arms are structured such that the quantity of visits is similar to allow for equivalent contact between groups. In both arms, participants will begin with supervised sessions 3 times per week during the 12-week acute phase of the study. Supervised sessions will be conducted as one-on-one (i.e., individual) sessions, although other participants may be exercising at the same time. Following the 12-week acute phase, participants will begin a 6-month continuation phase during which time they will attend one weekly supervised DEI or HEI session

Is There an Association between Advanced Paternal Age and Endophenotype Deficit Levels in Schizophrenia?

The children of older fathers have increased risks of developing schizophrenia spectrum disorders, and among those who develop these disorders, those with older fathers present with more severe clinical symptoms. However, the influence of advanced paternal age on other important domains related to schizophrenia, such as quantitative endophenotype deficit levels, remains unknown. This study investigated the associations between paternal age and level of endophenotypic impairment in a well-characterized family-based sample from the Consortium on the Genetics of Schizophrenia (COGS). All families included at least one affected subject and one unaffected sibling. Subjects met criteria for schizophrenia (probands; n = 293) or were unaffected first-degree siblings of those probands (n = 382). Paternal age at the time of subjects’ birth was documented. Subjects completed a comprehensive clinical assessment and a battery of tests that measured 16 endophenotypes. After controlling for covariates, potential paternal age–endophenotype associations were analyzed using one model that included probands alone and a second model that included both probands and unaffected siblings. Endophenotype deficits in the Identical Pairs version of the 4-digit Continuous Performance Test and in the Penn Computerized Neurocognitive Battery verbal memory test showed significant associations with paternal age. However, after correcting for multiple comparisons, no endophenotype was significantly associated with paternal age. These findings suggest that factors other than advanced paternal age at birth may account for endophenotypic deficit levels in schizophrenia

The Super-Earth Opportunity - Search for Habitable Exoplanets in the 2020s

The recent discovery of a staggering diversity of planets beyond the Solar System has brought with it a greatly expanded search space for habitable worlds. The Kepler exoplanet survey has revealed that most planets in our interstellar neighborhood are larger than Earth and smaller than Neptune. Collectively termed super-Earths and mini-Neptunes, some of these planets may have the conditions to support liquid water oceans, and thus Earth-like biology, despite differing in many ways from our own planet. In addition to their quantitative abundance, super-Earths are relatively large and are thus more easily detected than true Earth twins. As a result, super-Earths represent a uniquely powerful opportunity to discover and explore a panoply of fascinating and potentially habitable planets in 2020 - 2030 and beyond.Comment: Science white paper submitted to the 2020 Astronomy and Astrophysics Decadal Surve

Emotional Labor in Mathematics: Reflections on Mathematical Communities, Mentoring Structures, and EDGE

Terms such as "affective labor" and "emotional labor" pepper feminist critiques of the workplace. Though there are theoretical nuances between the two phrases, both kinds of labor involve the management of emotions; some acts associated with these constructs involve caring, listening, comforting, reassuring, and smiling. In this article I explore the different ways academic mathematicians are called to provide emotional labor in the discipline, thereby illuminating a rarely visible component of a mathematical life in the academy. Underlying this work is my contention that a conceptualization of labor involved in managing emotions is of value to the project of understanding the character, values, and boundaries of such a life. In order to investigate the various dimensions of emotional labor in the context of academic mathematics, I extend the basic framework of Morris and Feldman [33] and then apply this extended framework to the mathematical sciences. Other researchers have mainly focused on the negative effects of emotional labor on a laborer's physical, emotional, and mental health, and several examples in this article align with this framing. However, at the end of the article, I argue that mathematical communities and mentoring structures such as EDGE help diminish some of the negative aspects of emotional labor while also accentuating the positives.Comment: Revised version to appear in the upcoming volume A Celebration of EDGE, edited by Sarah Bryant, Amy Buchmann, Susan D'Agostino, Michelle Craddock Guinn, and Leona Harri

Challenges in the implementation of the NeoOBS study, a global pragmatic observational cohort study, to investigate the aetiology and management of neonatal sepsis in the hospital setting

Neonatal sepsis is a significant cause of mortality and morbidity in low- and middle-income countries. To deliver high-quality data studies and inform future trials, it is crucial to understand the challenges encountered when managing global multi-centre research studies and to identify solutions that can feasibly be implemented in these settings. This paper provides an overview of the complexities faced by diverse research teams in different countries and regions, together with actions implemented to achieve pragmatic study management of a large multi-centre observational study of neonatal sepsis. We discuss specific considerations for enrolling sites with different approval processes and varied research experience, structures, and training. Implementing a flexible recruitment strategy and providing ongoing training were necessary to overcome these challenges. We emphasize the attention that must be given to designing the database and monitoring plans. Extensive data collection tools, complex databases, tight timelines, and stringent monitoring arrangements can be problematic and might put the study at risk. Finally, we discuss the complexities added when collecting and shipping isolates and the importance of having a robust central management team and interdisciplinary collaborators able to adapt easily and make swift decisions to deliver the study on time and to target. With pragmatic approaches, appropriate training, and good communication, these challenges can be overcome to deliver high-quality data from a complex study in challenging settings through a collaborative research network