1,474 research outputs found

    Analysis of potential flow around two-dimensional body by finite element method

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    The paper presents a numerical method for analyzing the potential flow around two dimensional body such as single circular cylinder, NACA0012 hydrofoil and double circular cylinders by finite element method. The numerical technique is based upon a general formulation for the Laplace’s equation using Galerkin technique finite element approach. The solution of the systems of algebraic equations is approached by Gaussian elimination scheme. Laplace’s equation is expressed in terms of both steam function and velocity potential formulation. A finite element program is developed in order to analyze the result. The contours of stream and velocity potential function are drawn. The contour of stream function exhibits the characteristics of potential flow and does not intersect each other. The calculated pressure co-efficient shows the pressure decreasing around the forwarded face from the initial total pressure at the stagnation point and reaching a minimum pressure at the top of the cylinder

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    Association between thyroid disorders and abnormal uterine bleeding in reproductive ages

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    Background: Abnormal uterine bleeding (AUB) means any bleeding that is not normal in amount, duration, frequency, and cyclicity. It is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there are no structural defects in the genital tract. One of the most common associations with AUB is thyroid dysfunctions. Hence, this study aimed to see the incidence of thyroid-related disorders in AUB and also to assess the menstrual pattern.Methods: A total 100 women suffering from AUB who presented to OPD of the gynecology department of L D Hospital Srinagar, Jammu and Kashmir were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with a previously known thyroid disorder, abortion history within 3 months, etc. Thyroid function tests were done in all along with ultrasonography of the pelvis region. Data were analyzed using SPSS software v.23.0. and Microsoft office 2007.Results: The bleeding abnormality that was found in most of the women was heavy menstrual bleeding. Out of the 100 patients taken into study 11 had thyroid disorders, out of which subclinical hypothyroidism was most prevalent accounting for 8 cases, 2 cases were found to have hypothyroidism and 1 case of hyperthyroidism was detected.Conclusions: Abnormal uterine bleeding has a strong association with thyroid disorders. The most common type of disorder is subclinical hypothyroidism. Thus, all patient of AUB must be evaluated for thyroid dysfunction

    Angelica archengelica extract induced perturbation of rat skin and tight junctional protein (ZO-1) of HaCaT cells

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    "n  Background and purpose of the study: Herbal enhancers compared to the synthetic ones have shown less toxis effects. Coumarins have been shown at concentrations inhibiting phospoliphase C-Y (Phc-Y) are able to enhance tight junction (TJ) permeability due to hyperpoalation of Zonolous Occludense-1 (ZO-1) proteins. The purpose of this study was to evaluate the influence of ethanolic extract of Angelica archengelica (AA-E) which contain coumarin on permeation of repaglinide across rat epidermis and on the tight junction plaque protein ZO-1 in HaCaT cells. "n Methods: Transepidermal water loss (TEWL) from the rat skin treated with different concentrations of AA-E was assessed by Tewameter. Scanning and Transmission Electron Microscopy (TEM) on were performed on AA-E treated rat skin portions. The possibility of AA-E influence on the architecture of tight junctions by adverse effect on the cytoplasmic ZO-1 in HaCaT cells was investigated. Finally, the systemic delivery of repaglinide from the optimized transdermal formulation was investigated in rats. "n Results: The permeation of repaglinide across excised rat epidermis was 7-fold higher in the presence of AA-E (5% w/v) as compared to propylene glycol:ethanol (7:3) mixture. The extract was found to perturb the lipid microconstituents in both excised and viable rat skin, although, the effect was less intense in the later. The enhanced permeation of repaglinide across rat epidermis excised after treatment with AA-E (5% w/v) for different periods was in concordance with the high TEWL values of similarly treated viable rat skin. Further, the observed increase in intercellular space, disordering of lipid structure and corneocyte detachment indicated considerable effect on the ultrastructure of rat epidermis. Treatment of HaCaT cell line with AA-E (0.16% w/v) for 6 hrs influenced ZO-1 as evidenced by reduced immunofluorescence of anti-TJP1 (ZO-1) antibody in Confocal Laser Scanning Microscopy studies (CLSM) studies. The plasma concentration of repaglinide from transdermal formulation was maintained higher and for longer time as compared to oral administration of repaglinide. "n Major conclusion: Results suggest the overwhelming influence of Angelica archengelica in enhancing the percutaneous permeation of repaglinide to be mediated through perturbation of skin lipids and tight junction protein (ZO-1)

    Assessment of antibacterial activity of three plants used in Pakistan to cure respiratory diseases

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    The in vitro antimicrobial activity of Justicia adhatoda, Glycyrrhiza glabra and Hyssopus officinalis extracts were studied against selected bacteria by using agar well diffusion assay. Methanol, ethanol, chloroform, diethyl-ether and aqueous extracts were tested in crude form for antibacterial activity against Bacillus subtillus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium and Staphylococcus aureus. Maximum antibacterial activity was exhibited by all the three plant extracts. The results obtained with P. aeruginosa were particularly interesting since it was not inhibited by the antibiotic used but the tested plant extracts effectively inhibited the growth of P. aeruginosa. Themethanolic extract of J. adhatoda was effective against S. typhimurium. All the plants extract in water were effective against spore forming of B. subtillus while S. aureus and E. coli were not effectively inhibited by extracts of tested plants. The results of analysis of variance have shown significant differences between the species, treatments and interaction between the species and treatments. However, the differences were non-significant between the treatments for G. glabra. The results indicatethat J. adhatoda, G. glabra and H. officinalis present a noteworthy potential of antibacterial activities

    A Novel Dataset for English-Arabic Scene Text Recognition (EASTR)-42K and Its Evaluation Using Invariant Feature Extraction on Detected Extremal Regions

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    © 2019 IEEE. The recognition of text in natural scene images is a practical yet challenging task due to the large variations in backgrounds, textures, fonts, and illumination. English as a secondary language is extensively used in Gulf countries along with Arabic script. Therefore, this paper introduces English-Arabic scene text recognition 42K scene text image dataset. The dataset includes text images appeared in English and Arabic scripts while maintaining the prime focus on Arabic script. The dataset can be employed for the evaluation of text segmentation and recognition task. To provide an insight to other researchers, experiments have been carried out on the segmentation and classification of Arabic as well as English text and report error rates like 5.99% and 2.48%, respectively. This paper presents a novel technique by using adapted maximally stable extremal region (MSER) technique and extracts scale-invariant features from MSER detected region. To select discriminant and comprehensive features, the size of invariant features is restricted and considered those specific features which exist in the extremal region. The adapted MDLSTM network is presented to tackle the complexities of cursive scene text. The research on Arabic scene text is in its infancy, thus this paper presents benchmark work in the field of text analysis

    Arabic cursive text recognition from natural scene images

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    © 2019 by the authors. This paper presents a comprehensive survey on Arabic cursive scene text recognition. The recent years' publications in this field have witnessed the interest shift of document image analysis researchers from recognition of optical characters to recognition of characters appearing in natural images. Scene text recognition is a challenging problem due to the text having variations in font styles, size, alignment, orientation, reflection, illumination change, blurriness and complex background. Among cursive scripts, Arabic scene text recognition is contemplated as a more challenging problem due to joined writing, same character variations, a large number of ligatures, the number of baselines, etc. Surveys on the Latin and Chinese script-based scene text recognition system can be found, but the Arabic like scene text recognition problem is yet to be addressed in detail. In this manuscript, a description is provided to highlight some of the latest techniques presented for text classification. The presented techniques following a deep learning architecture are equally suitable for the development of Arabic cursive scene text recognition systems. The issues pertaining to text localization and feature extraction are also presented. Moreover, this article emphasizes the importance of having benchmark cursive scene text dataset. Based on the discussion, future directions are outlined, some of which may provide insight about cursive scene text to researchers
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