Histomorphometry aspect of thyroid gland and biochemical profile in pregnant and non-pregnant dromedary camels

Modulation of body physiology and metabolism is a prerequisite for successful pregnancy in camels, which is about a year and few months. The present study was carried out to verify the effect of pregnancy on histomorphometry and functional traits of thyroid gland, as well as some biochemical indices of liver and kidney functions and mineral profile in one humped camels, under Egyptian climatic conditions or desert conditions. The thyroid tissues were fixed in 10% formalin solution and processed following routine histological techniques after gross examination and biometric assessment. Serum levels of thyroid hormones (triiodothyronine, thyroxineand thyroid stimulating hormone), serum blood metabolites (total bilirubin, blood urea nitrogen and creatinine), liver enzymatic activity (aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP)), and minerals (sodium, potassium, calcium and phosphorus) were estimated in pregnant (n=30) and non-pregnant (n=30) camels. There were no significant differences between the right and left thyroid lobes between pregnant and non-pregnant camel. Pregnant status in camels had insignificant influence on histological and functional traits of thyroid as well as serum blood metabolites, liver enzymes and minerals levels, as compared with non-pregnant animals during the first six months of pregnancy. Therefore, reproductive status (during early pregnancy) has no substantial effect on camel physiological mechanisms or metabolic activity.Key words: Biochemical, dromedary, histology, thyroid gland, thyroid hormones

Ictal asystole: a case presentation

Abstract Background Epileptic seizures can lead to cardiac arrhythmias. The arrhythmias may be in the form of tachycardia, bradycardia or asystole. Ictal bradycardia and asystole can lead to sudden unexpected death. Case presentation A case report of a 40-year-old male with complex partial temporal lobe epilepsy. He has coincident attacks of fall and pallor. The patient underwent simultaneous electrocardiogram (ECG) and video electroencephalogram (EEG) monitoring. The slow activity in EEG coincide with the appearance of bradycardia in ECG then cardiac asystole which clinically correspond to the patient syncope. After insertion of a cardiac pacemaker, only complex partial attacks develop with a marked reduction in frequency and no more fall attacks. Conclusion Epileptic seizures can present with cardiac arrhythmias, with ictal asystole leading to sudden unexpected death. Simultaneous EEG and ECG are essential for the diagnosis. A cardiac pacemaker can be lifesaving for patients with ictal arrhythmias