CLASSICAL ASHTAVAIDYAN AYURVEDIC THERAPY IN THE FUNCTIONAL IMPROVEMENT OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: CASE STUDY

Background: Systemic lupus erythematosus is a systemic auto immune connective tissue disease that can affect any part of the body. The disease has no direct reference in Ayurvedic texts. Considering the symptomatology, it can be compared with Upadrava of Vatarakta. Methodology: In this study, 3 patients (age group between 15– 60 yrs) diagnosed SLE with the help of ACR criteria after assessing both objective and subjective parameters have undergone the prescribed classical Ayurvedic treatments, in both IP and OP level to evaluate its effect in the functional improvement. The study period was totally 57 days which included 21 days each at inpatient and outpatient basis and 15 days of follow up. Initially Sathaila Shastika Pinda Sweda was done for first 7 days followed by Takradhara for another 7 days. Consecutively Abhyanga with Pinda taila and Thalam with Amalaki were done for next 7 days. Then treatment was done on OP basis with internal medicines. Result: Results shows that the prescribed Ayurvedic treatments helped to control the progressive signs and symptoms. The quality of life and range of movements of the affected joints improved. Major difference showing a good improvement in carrying out the day today life activities was noted. Conclusion: Traditional Ashtavaidyan Ayurveda therapy is found effective in controlling the progressive symptoms of patients and improvement in functional ability of the patients with SLE. More over there was no adverse drug reaction recorded during as well there was significant change observed in liver and renal function tests. This indicates that the therapy is safe without producing any complication or side effects

EFFECT OF CLASSICAL AYURVEDIC TREATMENT IN THE FUNCTIONAL IMPROVEMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS

Arthritis and various musculoskeletal disorders are the leading causes of disability in persons between 18 to 65 years of age and are common causes of disability related to employment. Among them Rheumatoid arthritis is a common clinical condition characterized by pain, stiffness and inflammation of joints with varying degree of disability. In this study 50 patients (age group between 20-60 yrs) diagnosed as RA after assessing both objective and subjective parameters have undergone the prescribed classical Ayurvedic treatments, both IP and OP level to evaluate its effect in the functional improvement. The study period was totally 57 days which includes 21 days each at inpatient and outpatient basis and 15 days of follow up. Initial course was Ama pachana treatments for 7 days. It includes Pachana medicines internally and Ruksha pottali sweda externally. Next 14 days, Samana medicines internally and Pathra pottali sweda externally were given. Same internal medicines and oil application were continued for next 21 days as outpatient. The response of treatment was assessed periodically with respective parameters and were showed significant effect. The improvement in functional assessment evaluated by using the Das 28 score, disability index, quality of life index -SF36 and global assessment of disease activity scale are all found significant changes. The lab parameters used to evaluate the liver and kidney function did not show any adverse changes that shows the prescribed treatment is safe

Classical Ashtavaidyan Ayurvedic Therapy in the functional improvement of patients of Psoriatic Arthritis - An open label, single arm exploratory clinical study

Background: Arthritis and various musculoskeletal disorders are the leading cause of disability in persons between 18 to 65 years of age. Psoriatic arthritis simulates Ayurvedic descriptions of the clinical syndrome - Vatarakta. The study has been designed to evaluate the effectiveness of classical Ashtavaidyan methods of Ayurvedic intervention in the management of psoriatic arthritis and to assess the safety of the therapy. Methodology: Diagnosed cases of psoriatic arthritis (n=30) (20-60 yrs) have undergone the prescribed classical Ashtavaidyan Ayurvedic therapies. The total study period was 57 days which included 21 days each at inpatient and outpatient basis and 15 days of follow up. Initially modified Takradhara was performed along with internal medications for first 14 days; later same internal medication was continued with Sarvanga Abhyanga (therapeutic massage) with Pinda Taila and Vajraka Ghrita in 3:1 ratio externally and Amalaki Thalam for next 7 days. Same internal medicines and oil application were continued for next 21 days as outpatient. Results: The response to treatment was assessed periodically with respective parameters and showed highly significant improvement (P<0.001). There was significant reduction in PASI score and also significant changes in functional parameters related to psoriatic arthritis evaluated by using the visual analogue pain scale, DAS score, disability index scores and SF-36 (quality of life Index). The laboratory parameters used to evaluate the liver and renal functions did not show any significant changes that indicate the prescribed treatment is safe. Conclusion: Traditional Ashtavaidyan Ayurveda therapy is effective in reducing the skin lesions and improving functional ability in Vatarakta vis-à-vis psoriatic arthritis over a period of 42 days. Moreover, there was no adverse drug reaction recorded as well no significant change observed in liver and renal function tests

The Effectiveness of Patrapottali Sveda, Thailadhara, and Panchathiktaka Ksheera Ghruta to Treat Osteoarthritis of Knee (Sandhivata)

Currently, arthritis is a throbbing illness that affects people all over the world. Osteoarthritis is the most common type of arthritis out of all the many variations. This is frequently observed in later stages of life. The effectiveness of Patrapottali sveda, Thailadhara for external administration, and Panchathiktaka ksheera ghruta for internal administration to treat osteoarthritis in the knee was investigated in light of the significant handicap caused by the condition. Methodology: In the present study 60 participants having osteo-arthritis of Knee and patients satisfying the inclusion criteria were recruited to the study. The total time period of the study was 60 days with 21 days of IP treatment and 24 days of OP treatment. The 21 days of treatment, included Valuka sveda for 1-3days followed by internal administration of Panchatiktaka ksheera kwatha and Panchatiktaka guggulu ghrita along with Pradesika Patrapottali sveda for 7 days along with internal medication Pradesika thaila dhara with Ketakeemooladi thaila was done, last 4 days, only internal medicines. Then in OP level for 24 days by the same internal medicines and application of Ketakeemooladi thaila on affected knee joint. The follow up for the completed cases were done after 15 days. Results and Conclusion: The responses of the treatment were satisfactory. The treatment results showed significant improvement in the functional ability of the patients. The functional parameters, VAS, WOMAC scale and SF36 showed significant improvement. The laboratory parameters used to evaluate the liver and kidney functions did not show any significant change that indicates the prescribed treatment is safe