35 research outputs found
Élaboration d'un milieu de culture à base d'eaux usées industrielles pour la production d'un consortium d'algues-bactéries à des fins énergétiques
Seismic hazard assessment in Menton, France: Topographical site effect zoning considering a semi-empirical approach and a Machine Learning scheme
The presence of topography influences the seismic ground motion and may
result in strong amplifications, generally at the top of hills and reliefs. The
increasing urbanization of hills requires an accurate estimation of these
effects even in areas of moderate seismicity. The simplified coefficients
provided by the Eurocodes8 do not depend on the frequency and underestimate the
amplification in many situations, which justifies the development of new
methods based on easily accessible data. The city of Menton, located in the
southeast of France, between the Alps and the Ligurian basin, is one of the
most exposed metropolitan cities. We propose a study of topographic effects
applied to the Menton area. Topographic amplification is calculated, on a wide
frequency band, using the Frequency-Scaled Curvature method, from a DEM and an
average value of the shear wave velocity. We then propose to apply an automatic
clustering approach to classify the amplification curves into five groups with
similar properties. We then deduce a first microzonation map of the topographic
effects in the Menton area
Cultivation de microalgues avec des effluents gazeux d'une cimenterie afin de réduire les gaz à effet de serre
Recherche de molécules d'intérêt dans un consortium de microalgues cultivé en eaux usées industrielles
Phytochemical Screening of Quaking Aspen (Populus tremuloides) Extracts by UPLC-QTOF-MS and Evaluation of their Antimicrobial Activity
The continual emergence of pathogen resistance is a recurring challenge and pushes for the development of antimicrobial compounds. Here, we investigated compounds from quaking aspen trees (Populus tremuloides) as potential antimicrobial agents. Several extractions using different solvents were realized, and corresponding antimicrobial activity was tested against eight microorganisms. Results revealed that polar extraction solvents including water, ethanol and methanol gave the best extraction yields (\u3e15.07%). Minimal inhibition concentration (MIC) and minimal bactericidal/fungicidal concentration (MBC/MFC) demonstrated that water extracts had the best antimicrobial activity by a weak to moderate inhibition of growth of all eight tested microorganisms in addition to having a bactericidal effect on three of them. The quaking aspen methanol extract also displayed antimicrobial activity but to a lower level than the water extract. Ultra-performance liquid chromatography quadrupole time-of flight mass spectrometry (UPLC-QTOF-MS) analysis led to the identification of 92 compounds, mainly polyphenols in both extracts, with 22 molecules previously known for their antimicrobial properties. According to the relative abundance, 4-hydroxybenzaldehyde (5.44% in methanol extract) and kaempferol (5.03% in water extract) were the most abundant antimicrobial compounds. Among antimicrobial molecules identified, nine were from the flavonoid family. The results of our study demonstrate the interest of using quaking aspen as source of antimicrobial compounds
Le risque : un modèle conceptuel d'intégration
The following project report is the first of a sequence which will focus on integrated risk management. This report presents a conceptual model which goal is to define the concept of risk. This conceptual model integrates the definitions of multiple domains having an interest in risk management. With the model, a terminology is proposed. This conceptual model is a foundation upon which it will be possible to exchange methods and measures of risk between domains. Ce rapport de projet est le premier d'une série qui s'intéressera à la gestion intégrée du risque. Dans l'objectif de répondre à la question « qu'est-ce que le risque? », un modèle conceptuel définissant le concept du risque est proposé. Ce modèle conceptuel intègre les définitions du risque de différentes disciplines. Une terminologie a été élaborée pour accompagner le modèle. Ce modèle conceptuel tente d'élaborer une base à partir de laquelle pourra se faire l'échange de méthodes et de mesures entre les domaines s'intéressant au risque.Risk, integrated risk management, definition, integration, Risque, gestion intégrée du risque, définition, intégration
Contributing factors of unmet needs among young adult survivors of childhood acute lymphoblastic leukemia with comorbidities
Purpose: This study aimed to: (1) describe the domains and levels of unmet needs of young adult survivors of childhood acute lymphoblastic leukemia (cALL) with comorbidities, and (2) to explore the factors associated with higher levels of unmet needs. Unmet need was considered as supportive care needs not met.
Methods: The most vulnerable cALL survivors from the PETALE study cohort completed the Short-Form Survivor Unmet Needs Survey, the Brief Pain Inventory and the 15D instrument of health-related quality of life. Demographic and clinical information, including comorbidities, were obtained from medical records or self-reporting. The participants' needs and contributing factors to their needs were evaluated using nonparametric tests.
Results: Of the 72 participants, 9 (13%) reported moderate/high levels of overall unmet needs. “Worry about earning money” (56%) and “Dealing with feeling tired” (51%) were the most frequent unmet needs (all levels combined). The factors associated significantly with any domain of unmet needs were: having a comorbidity, reporting altered functional health status, high ALL risk status, pain, age (<26 years), and having previously received psychological support.
Conclusion: A minority of young adult survivors of cALL with comorbidities interviewed reported moderate/high levels of unmet needs. However, financial concerns and emotional health and relationship are the two domains of greatest need. Survivors with altered health condition are most at risk of experiencing moderate/high levels of unmet needs. If confirmed in larger samples, interventions should target modifiable contributors of unmet needs such as physical health and comfort, fatigue, and emotional health