Structural Characterization of the NodD Transcription Factor

Abstract Using computer analysis and modeling we studied NodD transcription factor which controls expression of nodulation genes of symbiotic nitrogen-fixing bacteria. On the basis of the amino acid sequences it was predicted that in the secondary structure of NodD protein it must be present ten alpha helices and three beta sheets which form two do mains after folding. Since NodD acts in oligo meric mode, it was analy zed all four known for other similar factors of transcription ways of assembly into dime rs. Using molecular docking the probable mechanism o f NodD act ivation by binding of low molecular weight inducer (on the model o f luteolin) was clarified

Associated production of prompt J/ψJ/\psi and Υ\mathit{\Upsilon} mesons in pppp collisions at s=13 TeV\sqrt{s}=13\,\mathrm{TeV}

International audienceThe associated production of prompt $J/\psi$ and $\mathit{\mathit{\Upsilon}}$ mesons in $pp$ collisions at a centre-of-mass energy of $\sqrt{s}=13\,\mathrm{TeV}$ is studied using LHCb data, corresponding to an integrated luminosity of $4\,\mathrm{fb}^{-1}$. The measurement is performed for $J/\psi$ ($\mathit{\Upsilon}$) mesons with a transverse momentum $p_{\mathrm{T}}<10\,(30)\,\mathrm{GeV}/c$ in the rapidity range $2.0<y<4.5$. In this kinematic range, the cross-section of the associated production of prompt $J/\psi$ and $\mathit{\Upsilon}(1S)$ mesons is measured to be $133 \pm 22 \pm 7 \pm 3 \, \mathrm{pb}$, with a significance of $7.9\,\sigma$, and that of prompt $J/\psi$ and $\mathit{\Upsilon}(2S)$ mesons to be $76\pm 21 \pm 4 \pm 7 \, \mathrm{pb}$, with a significance of $4.9\,\sigma$. The first uncertainty is statistical, the second systematic, and the third due to uncertainties on the used branching fractions. This is the first observation of the associated production of $J/\psi$ and $\mathit{\Upsilon}(1S)$ in proton-proton collisions. Differential cross-sections are measured as function of variables that are sensitive to kinematic correlations between the $J/\psi$ and $\mathit{\Upsilon}(1S)$ mesons. The effective cross-sections of the associated production of prompt $J/\psi$ and $\mathit{\Upsilon}$ mesons are obtained and found to be compatible with measurements using other particle productions

Search for the lepton-flavour violating decays B0→K∗0μ±e∓B^0 \to K^{*0} \mu^\pm e^\mp and Bs0→ϕμ±e∓B_s^0 \to \phi \mu^\pm e^\mp

A search for the lepton-flavour violating decays $B^0 \to K^{*0} \mu^\pm e^\mp$ and $B_s^0 \to \phi \mu^\pm e^\mp$ is presented, using proton-proton collision data collected by the LHCb detector at the LHC, corresponding to an integrated luminosity of $9\,\text{fb}^{-1}$. No significant signals are observed and upper limits of \begin{align} {\cal B}( B^0 \to K^{*0} \mu^+ e^- ) &< \phantom{1}5.7\times 10^{-9}~(6.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^- e^+ ) &< \phantom{1}6.8\times 10^{-9}~(7.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^\pm e^\mp ) &< 10.1\times 10^{-9}~(11.7\times 10^{-9}),\newline {\cal B}( B_s^0 \to \phi \mu^\pm e^\mp ) &< 16.0\times 10^{-9}~(19.8\times 10^{-9}) \end{align} are set at $90\%~(95\%)$ confidence level. These results constitute the world's most stringent limits to date, with the limit on the decay $B_s^0 \to \phi \mu^\pm e^\mp$ the first being set. In addition, limits are reported for scalar and left-handed lepton-flavour violating New Physics scenarios.A search for the lepton-flavour violating decays B$^{0}$ → K$^{*0}$μ$^{±}$e$^{∓}$ and ${B}_s^0$→ ϕμ$^{±}$e$^{∓}$ is presented, using proton-proton collision data collected by the LHCb detector at the LHC, corresponding to an integrated luminosity of 9 fb$^{−1}$. No significant signals are observed and upper limits of${\displaystyle \begin{array}{c}\mathcal{B}\left({B}^0\to {K}^{\ast 0}{\mu}^{+}{e}^{-}\right)<5.7\times {10}^{-9}\left(6.9\times {10}^{-9}\right),\\ {}\mathcal{B}\left({B}^0\to {K}^{\ast 0}{\mu}^{-}{e}^{+}\right)<6.8\times {10}^{-9}\left(7.9\times {10}^{-9}\right),\\ {}\mathcal{B}\left({B}^0\to {K}^{\ast 0}{\mu}^{\pm }{e}^{\mp}\right)<10.1\times {10}^{-9}\left(11.7\times {10}^{-9}\right),\\ {}\mathcal{B}\left({B}_s^0\to \phi {\mu}^{\pm }{e}^{\mp}\right)<16.0\times {10}^{-9}\left(19.8\times {10}^{-9}\right)\end{array}}$are set at 90% (95%) confidence level. These results constitute the world’s most stringent limits to date, with the limit on the decay ${B}_s^0$→ ϕμ$^{±}$e$^{∓}$ the first being set. In addition, limits are reported for scalar and left-handed lepton-flavour violating New Physics scenarios.[graphic not available: see fulltext]A search for the lepton-flavour violating decays $B^0 \to K^{*0} \mu^\pm e^\mp$ and $B_s^0 \to \phi \mu^\pm e^\mp$ is presented, using proton-proton collision data collected by the LHCb detector at the LHC, corresponding to an integrated luminosity of $9\,\text{fb}^{-1}$. No significant signals are observed and upper limits of \begin{align} {\cal B}( B^0 \to K^{*0} \mu^+ e^- ) &< \phantom{1}5.7\times 10^{-9}~(6.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^- e^+ ) &< \phantom{1}6.8\times 10^{-9}~(7.9\times 10^{-9}),\newline {\cal B}( B^0 \to K^{*0} \mu^\pm e^\mp ) &< 10.1\times 10^{-9}~(11.7\times 10^{-9}),\newline {\cal B}( B_s^0 \to \phi \mu^\pm e^\mp ) &< 16.0\times 10^{-9}~(19.8\times 10^{-9}) \end{align} are set at $90\%~(95\%)$ confidence level. These results constitute the world's most stringent limits to date, with the limit on the decay $B_s^0 \to \phi \mu^\pm e^\mp$ the first being set. In addition, limits are reported for scalar and left-handed lepton-flavour violating New Physics scenarios