Seis personajes en busca de “un tercer lugar”. La inseguridad y afán de encontrar al otro y sí mismo en Un tercer lugar de Denise Despeyroux

Denise Despeyroux en su obra Un tercer lugar (2016) ofrece una propuesta irónica en torno a la vida humana y a las relaciones interpersonales. Los personajes de este drama están en un constante proceso de búsqueda de sí mismos, del cambio y la transformación. La inseguridad e inestabilidad de las relaciones interpersonales son los rasgos autistas que se enumeran en las teorías de la cognición emocional. El objetivo de mi ponencia es hacer un análisis del drama Un tercer lugar en el marco teórico de la teoría de la cognición emocional. Despeyroux presenta tres parejas neuróticas que se sienten incapaces de comprenderse. Los rasgos de la inestabilidad emocional y las diferencias de horizonte de expectativas son del máximo interés para la dramaturga

Aripiprazole in treatment of Gilles de la Tourette syndrome – New therapeutic option

Aripiprazole is a dopamine D2- and serotonin 5-hydroxytryptamine (5-HT)1A receptor partial agonist and 5-HT2A receptor antagonist primarily used for the treatment of schizophrenia, bipolar disorder or depression with psychotic ideation. However, recently a number of new possible indications have been suggested, among them Gilles de la Tourette syndrome (GTS). In two randomized, double-blind, placebo-controlled studies in children and adolescents with GTS has been confirmed the efficacy of aripiprazole in tic reduction. In comparison to other neuroleptics, aripiprazole seems to be similarly effective. What is more, the number and profile of possible adverse effects is also favorable. As a consequence, aripiprazole had been registered by Food and Drug Administration (FDA) for the treatment of tics and represents new therapeutic option in treatment of GTS

Między postmodernizmem a klasycyzmem, czyli o Fuzji młodości i starości w teorii kultury : rewizja kanonu w sztuce "Hölderlin" Alfonsa Vallejo w świetle teorii lęku przed wpływem

In one of his plays entitled Hölderlin Alfonso Vallejo establishes direct and indirectconnections with life and poetry of romantic poet Friedrich Hölderlin. We analyse traces one author in writings of another using the theory of anxiety of influence by Harold Bloom. The process of self-understanding and comprehension of the art leads, according to Bloom, through a number of stages: clinamen, tessera, kenosis, demonisation, askesis and apophrades. We try to detect techniques used by Vallejo in his artistic pattern and determine what are aesthetic and formal consequences of his endeavo

Phenomenology and Clinical Correlates of Stimulus-Bound Tics in Gilles de la Tourette Syndrome

Introduction: Stimulus-bound tics (SBTs) belong to stimulus-induced behaviors and are defined as tics that occur in response to internal or external stimuli. The aim of the study was to assess the prevalence and associations of SBTs with other stimulus-triggered behaviors, premonitory urges and stimulus sensitization in Gilles de la Tourette syndrome (GTS).Methods: We performed a prospective, one-registration study in a cohort of 140 consecutive patients with GTS. Duration of GTS was 10.6 ± 8.7 years (range: 0–39 years). SBTs were diagnosed during the interview.Results: SBTs occurred at some point in the lifetime of 20.7% of patients. The presence of SBTs in adults was four times as frequent as in children (35.5% vs. 9.0%) with the most frequent onset in adolescence (58.8%) and adulthood (29.4%). These tics started 9.1 ± 4.7 years after the onset of tics. One stimulus and mental stimulus preceded tics most frequently, 44.8 and 33.3%, respectively. There was no established pattern of tics triggered by stimuli. Multivariate logistic regression analysis showed significant associations of SBTs with age at evaluation, tic severity, and palilalia but not with any co-morbid psychiatric disorders. 80% of patients showed at least one stimulus-triggered behavior. Premonitory urges and stimulus sensitization were reported by 60.0 and 40.7% of patients, respectively. No significant correlations between SBTs, premonitory urges and stimulus sensitization were found.Conclusion: SBTs are a part of the tic spectrum and should be taken into account by clinicians who deal with GTS patients. These tics fall at the tic end of the continuum of stimulus-induced behaviors

Wymiar fraktalny prawdy i kłamstwa w sztuce "Fly-by" Alfonsa Vallejo : od Derridy i Levinasa do teorii samopodobieństwa jako metafory egzystencji

Theatre of Alfonso Vallejo presents complex psychic processes and therefore is barely realistic, on the contrary, it is based upon surrealistic visions adequate to diversity of human being. Although it seems chaotic, this chaos resembles network of infinite connections that produce, as a consequence, infinite number of questions and possible answers. To interpret the complexity of Vallejo's dramas we use theory of fractals and self-similarity in play Fly-b

The theatre of Alfonso Vallejo and the theatre of the absurd : revindication of canon in "El escuchador de hielo"

Alfonso Vallejo is one of the most famous playwrights of modern Spain. He is also a poet, a painter and a doctor. He combines all of those disciplines and this has its consequences in the construction of the drama. Vallejo tries to reach the fundaments of human soul, which is possible only when one rejects realistic aesthetics. Critics describe his theatre as existential, but also detect some characteristics of surrealism and the theatre of the absurd. We consider Vallejo's theatre as continuation of the theatre of the absurd, at least in some parts of his plays. The purpose of our work is to determine some elements of the theatre of the absurd in his play "El escuchador de hielo". Moreover, we would like to focus on the vanguardist tradition seen as part of canonic theatre and its relationship with Vallejo's plays.Alfonso Vallejo es uno de los dramaturgos más conocidos en la España contemporánea. Es, además, poeta, pintor y médico. La combinación de estas disciplinas tiene su repercusión en la construcción del universo teatral. Vallejo trata de llegar ante todo a las raíces del alma humana, lo cual solo es posible al rechazar las prácticas realistas. Los críticos describen su teatro como existencialista, con rasgos surrealistas y próximos al teatro del absurdo. A nuestro modo de ver Vallejo es un continuador del teatro del absurdo en su sentido amplio , al menos en parte de sus obras. El propósito de este trabajo es señalar los rasgos de este teatro del absurdo en "El escuchador de hielo" de Alfonso Vallejo. Es menester, además, ver los dramas de Vallejo como una continuación de la tradición vanguardista, considerando esta una parte del canon teatral

Dystonic tics in patients with Gilles de la Tourette syndrome

Clinical rationale for the study. Gilles de la Tourette syndrome (GTS) is a childhood onset disorder characterised by motor and vocal tics. Different types of motor tics may occur in GTS, including dystonic tics (DTs). Although DTs have been recognised as part of GTS symptomatology, little is known about their risk factors or about how often and at what age they appear in affected individuals. Aim of the study. The aim of our study was to investigate lifetime prevalence and clinical correlations of DTs in a Polish cohort of GTS patients. Material and methods. We performed a prospective, one-registration study in a cohort of 207 consecutive ambulatory patients (mean age: 16.5 ± 9.4 years, 131 children, 162 males) with GTS. Duration of GTS was 9.0 ± 8.0 years (range: 1–39 years). DTs were diagnosed during the interview. DTs were defined as slower and lasting longer than typical clonic tics, abnormal dystonia-like movements that led to a sustained, but not fixed, posture. Results. DTs occurred at some point in the lifetime of 73.9% (n = 153) of patients. The prevalence of DTs in adults and children was almost the same (p = 0.963). Age at onset of DTs was 9.9 ± 5.2 years with the most frequent onset in children (7–11 years, 74.4%, n = 64), followed by adolescence (12–18 years; 17.4%, n = 15) and adulthood (≥ 18 years, 8.1%, n = 7). DTs occurred 3.7 ± 4.2 years after tic onset. On average, patients suffered from 1.8 ± 1.7 types of DTs. The most frequent manifestations of DTs were: eyes (tightening resembling blepharospasm 84.3%, n = 129 and oculogyric crisis 45.8%, n = 70), trunk (dystonic postures 59.5%, n = 91), jaw (bruxism 34.6%, n = 53), neck (30.7%, n = 47), upper limb (26.1%, n = 40), and foot (20.9%, n = 32). Multivariate logistic regression analysis showed significant associations of DTs with the total number of simple, and the total number of complex, tics. Conclusions and clinical implications. DTs are early and frequent symptoms of GTS. They tend to localise in the facial area. DTs occur more frequently in individuals with a higher number of tics and probably add to the global impairment caused by tics. Key words: Gilles de la Tourette syndrome, dystonic tics, simple tics, complex tics, dystoni

Possible Role of the Endocannabinoid System in Tourette Syndrome

Tourette syndrome (TS) is a neuropsychiatric disorder with childhood onset. The core symptoms are motor and vocal tics. The majority of patients also suffer from psychiatric comorbidities. The pathophysiology of TS is not clear, but changes in different neurotransmitter systems—in particular the dopaminergic system—have been confirmed. Since there is increasing evidence that cannabis-based medicine (CBM) is effective in the treatment of TS, an involvement of the endocannabinoid system in the pathophysiology of TS has been suggested. The purpose of this chapter is to present existing evidence suggesting a pathophysiological role of the endocannabinoid system in TS and to summarize available data on beneficial treatment effects of CBM in patients with TS

Stalker z filmu A. Tarkowskiego jako „jurodiwy” i jako figura twórcy

The film Stalker by Andrei Tarkovsky is based on the novel Roadside Picnic by Strugatsky Brothers and it presents real and metaphoric travel of the main protagonist, Stalker, through the enigmatic Zone in search of ontological true. Stalker’s naivety and complete devotion to his mission resembles feeblemindness, that is why he could be described as ¨yurodivy¨, fool for Christ according to Eastern Orthodox ascetism. In our paper we also analyze Stalker as performer and artist that dedicates absolutely to his ideal