The risk factors for medical and psychoemotional disturbances after cesarean section

Catedra Obstetrică și Ginecologie, USMF „Nicolae Testemițanu”The aim of the present study was the analysis and the evaluation of the risk factors for the development of medical and psychoemotional disturbances during the early and late postoperatory periods in 100 patients after cesarean section. The level of influence of certain risk factors over medical and psychoemotional aspects was determined separately for each period with the help of Pearson correlation tables. Scopul studiului dat a fost analiza și evaluarea factorilor de risc pentru apariția disfuncțiilor medicale și psihoemoționale în perioada postoperatorie precoce și cea la distanță la 78 100 de paciente după operația cezariană. Cu ajutorul tabelelor de corelație Pearson a fost determinat nivelul de influență a anumitor factori de risc asupra aspectelor medicale și psihoemoționale, separat pentru fiecare perioadă

Operaţia cezariană: Aspecte medicale şi psihoemoţionale

Prin intermediul studiului dat s-au evaluat aspectele medicale (funcţia de lactaţie, funcţia menstruală, funcţia sexuală) şi psihoemoţionale (anxietatea reactivă şi de personalitate,depresia) la 100 de paciente după operaţia cezariană,cercetarea efectuându-se atât în perioada de lăuzie(postoperatorie precoce), cât şi în perioada postoperatorie la distanţă

Subclinical damage organ additional risk stratification patients with arterial hypertension

Departamentul Medicină Internă, Clinica Medicală N 1, USMF „Nicolae Testemiţanu”In order to assess subclinical organ damage in additional risk stratification in patients with hypertension were investigated 80 patients with essential hypertension. The data obtained have shown that patients with essential hypertension is a heterogeneous group of patients, which must be made individually. Most investigated patients showed a wide range of risk factors. Additional risk stratification with subclinical organ damage has proved the practical applicability of this score in predicting negative jumps. Additional risk assessment should be performed in order to select a differentiated approach and optimal treatment regimen. Additional risk optimization has as a consequence rational results in reducing cardiovascular morbidity and mortality, representing challenge for any clinician and scientific organizations that implement this approach useful in developing useful guidelines for detection, evaluation and treatment of essential arterial hypertension. Cu scopul evaluării afectării subclinice de organ în stratificarea riscului adiţional la pacienţii cu hipertensiune arterială au fost investigaţi 80 de pacienţii cu hipertensiune arterială esenţială. Datele obţinute au demonstrat că pacienţii cu hipertensiune arterială esenţială reprezintă un grup heterogen de bolnavi, abordarea cărora trebuie realizată în mod individual. Majoritatea pacienţilor cercetaţi au prezentat o gamă largă a factorilor de risc. Stratificarea riscului adiţional cu includerea afectarii subclinice de organ a demonstrat aplicabilitatea practică acestui scor în prognozarea salturilor nefaste. Evaluarea riscului adiţional trebuie efectuată în scopul abordării diferenţiate şi selectării unui regim optim de tratament. Optimizarea riscului adiţional, are drept consecinţă raţională reducerea morbidităţii şi mortalităţii cardiovasculare, reprezintă o provocare pentru orice clinician şi pentru organizaţiile ştiinţifice ce concretizează acest demers în elaborarea de ghiduri utile în detectarea, evaluarea şi tratarea hipertensiunii arteriale esenţiale

Gut Microbiota, Host Organism, and Diet Trialogue in Diabetes and Obesity

The gastrointestinal tract with its microbiota is a complex, open, and integrated ecosystem with a high environmental exposure. It is widely accepted that the healthy gut microbiotais essential for host homeostasis and immunostasis, harboring an enormous number and variety of microorganisms and genes tailored by hundreds of exogenous and intrinsic host factors. The occurrence of dysbiosis may contribute to host vulnerability and progression to a large spectrum of infectious and non-communicable diseases, including diabetes and obesity, two metabolic disorders that are showing an endemic trend nowadays. There is an urgent need to develop efficient strategies to prevent and treat metabolic disorders such as diabetes and obesity which are often associated with serious complications. In this paper, we give an overview on the implications of gut microbiota in diabesity, with a focus on the triangle gut microbiota—diet-host metabolism and on the way to manipulate the gut microbial ecosystem toward achieving novel diagnosis and predictive biomarkers with the final goal of reestablishing the healthy metabolic condition. The current research data regarding the precision/personalized nutrition suggest that dietary interventions, including administration of pre-, pro-, and syn-biotics, as well as antibiotic treatment should be individually tailored to prevent chronic diseases based on the genetic background, food and beverage consumption, nutrient intake, microbiome, metabolome, and other omic profiles

Adult respiratory distress syndrome in the peripartum period: a case report

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Spitalul Clinic Republican, Spitalul Clinic Municipal nr. 1Patologia respiratorie în perioada peripartum implică un risc major, atât pentru viaţa mamei, cât şi a copilului. Insuficienţa pulmonară acută creşte rata mortalităţii materne în sarcină până la 90%, comparativ cu 50-60% în afara sarcinii. Rata insuficienţei pulmonare primare este mică comparativ cu alte patologii asociate sarcinii, constituind în mediu 5%. În marea majoritate a cazurilor ea apare secundar, ca component al insuficienţei poliorganice. Modificarea fiziologiei pulmonare în perioada peripartum necesită optimizarea conduitei individuale atât în timpul sarcinii, cât şi la naştere. Tratamentul contemporan al insuficienţei respiratorii este destul de costisitor, necesitând un monitoring sofisticat şi individualizat.Respiratory pathology in pregnancy and labor involves a double risk, both for mother’s and child’s life. Acute pulmonary failure increases the rate of maternal mortality up to 90% during the pregnancy in comparison with 50-60% out of pregnancy. The incidence of pulmonary insufficiency is rather low in comparison with the other associated pregnancy pathology, established to 5%. In the most of the cases it occurs secondary as a compound of MODS. Pulmonary physiology is essentially modified in pregnancy, raising the necessity of peculiar pregnancy and labor management applied. The contemporary treatment of pulmonary insufficiency is rather expensive, requiring advanced and individualized monitoring

The stable angina pectoris complicated with a myocardic old infarction, unidentified in time, clinical case

Disciplina Cardiologie, Clinica Medicală nr.3, Departamentul Medicină Internă, USMF „Nicolae Testemiţanu”, IMSP SCM ”Sfânta Treime”Stable angina pectoris (AP) is the most common form of ischemic heart disease, which is characterized by constrictive retrosternal pain of short duration, dependent on exercise, with radiation to the jaw, shoulders, back, or arms, typically occurs with exertion or emotional stress and improved by rest or nitroglycerin administration. Atypical discomfort may occur in the epigastric region. The incidence of angina pectoris in most European countries is between 20,000 and 40000-1000000 inhabitants suffer where a higher frequency occurs in able-bodied men. [3] Patients with stable angina, who do not follow a treatment, can further develop atherosclerotic plaque instability with the installation of myocardial infarction. We present a clinical case of a man of 76 years with stable angina pectoris, who neglected antihypertensive and antianginal treatment, suffered a myocardial infarction with inapparent clinical, occasionally diagnosed in worsening of angina pectoris. Angina pectorală (AP) stabilă este cea mai frecventă formă a cardiopatiei ischemice, care se caracterizează prin dureri retrosternale constrictive de scurtă durată, dependente de efort fizic, cu iradiere în mandibulă, umeri, spate, sau braţe, apărut tipic la efort sau stres emoţional şi ameliorat in repaus sau la administrarea de nitroglicerină. Atipic, disconfortul poate să apară in regiunea epigastrică. Incidența anginei pectorale, în majoritatea ţărilor europene, oscilează între 20.000 şi 40.000 la 1.000.000 locuitori suferă, cu o frecvență mai înaltă de instalare la bărbați apți de muncă [3]. Pacienții cu angină stabilă, care nu respectă tratamentul, pot dezvolta ulterior instabilitatea plăcii aterosclerotice, cu instalarea infarctului miocardic. Prezentăm un caz clinic a unui bărbat, de 76 de ani cu angină pectorală stabilă, care a neglijat tratamentul hipotensiv și antianginal, a suportat un infarct miocardic cu clinică nemanifestă, ocazional diagnosticat la agravarea anginei pectorale

Methodology and implementation of the WHO European Childhood Obesity Surveillance Initiative (COSI)

Establishment of the WHO European Childhood Obesity Surveillance Initiative (COSI)has resulted in a surveillance system which provides regular, reliable, timely, andaccurate data on children's weight status—through standardized measurement ofbodyweight and height—in the WHO European Region. Additional data on dietaryintake, physical activity, sedentary behavior, family background, and schoolenvironments are collected in several countries. In total, 45 countries in the EuropeanRegion have participated in COSI. The first five data collection rounds, between 2007and 2021, yielded measured anthropometric data on over 1.3 million children. In COSI,data are collected according to a common protocol, using standardized instrumentsand procedures. The systematic collection and analysis of these data enables inter-country comparisons and reveals differences in the prevalence of childhood thinness,overweight, normal weight, and obesity between and within populations. Furthermore,it facilitates investigation of the relationship between overweight, obesity, and poten-tial risk or protective factors and improves the understanding of the development ofoverweight and obesity in European primary-school children in order to supportappropriate and effective policy responses.The authors gratefully acknowledge support through a grant from the Russian Government in the context of the WHO European Office for the Prevention and Control of NCDs. The ministries of health of Austria, Croatia, Greece, Italy, Malta, Norway, and the Russian Federation provided financial support for the meetings at which the protocol, data collection procedures, and analyses were discussed. Data collection in countries was made possible through funding from the following: Albania: WHO through the Joint Programme on Children, Food Security and Nutrition “Reducing Malnutrition in Children,” funded by the Millennium Development Goals Achievement Fund, and the Institute of Public Health. Austria: Federal Ministry of Labor, Social Affairs, Health and Consumer Protection of Austria. Bulgaria: Ministry of Health, National Center of Public Health and Analyses, and WHO Regional Office for Europe. Bosnia and Herzegovina: WHO country office support for training and data management. Croatia: Ministry of Health, Croatian Institute of Public Health, and WHO Regional Office for Europe. Czechia: Ministry of Health of the Czech Republic, grant number 17-31670A and MZCR—RVO EU 00023761. Denmark: Danish Ministry of Health. Estonia: Ministry of Social Affairs, Ministry of Education and Research (IUT 42-2), WHO Country Office, and National Institute for Health Development. Finland: Finnish Institute for Health and Welfare. France: Santé publique France (the French Agency for Public Health). Georgia: WHO. Greece: International Hellenic University and Hellenic Medical Association for Obesity. Hungary: WHO Country Office for Hungary. Ireland: Health Service Executive. Italy: Ministry of Health. Kazakhstan: Ministry of Health of the Republic of Kazakhstan, WHO, and UNICEF. Kyrgyzstan: World Health Organization. Latvia: Ministry of Health and Centre for Disease Prevention and Control. Lithuania: Science Foundation of Lithuanian University of Health Sciences and Lithuanian Science Council and WHO. Malta: Ministry of Health. Montenegro: WHO and Institute of Public Health of Montenegro. North Macedonia: Government of North Macedonia through National Annual Program of Public Health and implemented by the Institute of Public Health and Centers of Public Health; WHO country office provides support for training and data management. Norway: the Norwegian Ministry of Health and Care Services, the Norwegian Directorate of Health, and the Norwegian Institute of Public Health. Poland: National Health Programme, Ministry of Health. Portugal: Ministry of Health Institutions, the National Institute of Health, Directorate General of Health, Regional Health Directorates, and the kind technical support from the Center for Studies and Research on Social Dynamics and Health (CEIDSS). Romania: Ministry of Health. Russian Federation: WHO. San Marino: Health Ministry, Educational Ministry, and Social Security Institute and Health Authority. Serbia: WHO and the WHO Country Office (2015-540940 and 2018/873491-0). Slovakia: Biennial Collaborative Agreement between WHO Regional Office for Europe and Ministry of Health SR. Slovenia: Ministry of Education, Science and Sport of the Republic of Slovenia within the SLOfit surveillance system. Spain: Spanish Agency for Food Safety and Nutrition. Sweden: Public Health Agency of Sweden. Tajikistan: WHO Country Office in Tajikistan and Ministry of Health and Social Protection. Turkmenistan: WHO Country Office in Turkmenistan and Ministry of Health. Turkey: Turkish Ministry of Health and World Bank.info:eu-repo/semantics/publishedVersio