544 research outputs found

    Analysis of the flow and heat transfer characteristics for MHD free convection in an enclosure with a heated obstacle

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    Finite element method based on Galerkin weighted Residual approach is used to solve two-dimensional governing mass, momentum and energy equations for steady state, natural convection flow in presence of magnetic field inside a square enclosure. The cavity consists of three adiabatic walls and one constantly heated wall. A uniformly heated circular solid body is located at the centre of the enclosure. The aim of this study is to describe the effects of MHD on the flow and thermal fields in presence of such heated obstacle. The investigations are conducted for different values of Rayleigh number (Ra) and Hartmann number (Ha). Various characteristics of streamlines, isotherms and heat transfer rate in terms of the average Nusselt number (Nu) are presented for different parameters. The effect of physical parameter (D) is also shown here. The results indicate that the flow pattern and temperature field are significantly dependent on the above mentioned parameters

    Shifting Coalitions within the Youth Climate Movement in the US

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    How has the youth climate movement in the US grown since the Climate Strikes began and in what ways did it change as it grew? This article takes advantage of a unique dataset that includes surveys from activists who organized the nationally coordinated climate strikes in the US that began with Fridays for Future in spring 2019. Building on the research on alliance building and strategic coalitions, this article analyzes how the patterns of participation changed over the period of the study. We employ social network analysis to map the affiliation networks among the organizers of these events to assess the coalitions of groups involved and the shifting organizational landscape. Our analysis does not provide evidence that groups spanned the boundaries across movements, nor does it show that identity plays a role in coalition building in this movement. Instead, by mapping out the coalition of organizations within this movement and how connections among them change over time, we see clear evidence that this youth-led movement was reoriented by adult-led organizations. Our article concludes by considering how these findings suggest the future trajectory of the youth climate movement and its role in a ‘new climate politics’ in America

    A survey on subjecting electronic product code and non-ID objects to IP identification

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    Over the last decade, both research on the Internet of Things (IoT) and real-world IoT applications have grown exponentially. The IoT provides us with smarter cities, intelligent homes, and generally more comfortable lives. However, the introduction of these devices has led to several new challenges that must be addressed. One of the critical challenges facing interacting with IoT devices is to address billions of devices (things) around the world, including computers, tablets, smartphones, wearable devices, sensors, and embedded computers, and so on. This article provides a survey on subjecting Electronic Product Code and non-ID objects to IP identification for IoT devices, including their advantages and disadvantages thereof. Different metrics are here proposed and used for evaluating these methods. In particular, the main methods are evaluated in terms of their: (i) computational overhead, (ii) scalability, (iii) adaptability, (iv) implementation cost, and (v) whether applicable to already ID-based objects and presented in tabular format. Finally, the article proves that this field of research will still be ongoing, but any new technique must favorably offer the mentioned five evaluative parameters.Comment: 112 references, 8 figures, 6 tables, Journal of Engineering Reports, Wiley, 2020 (Open Access

    Heat treatment effect on the structural, morphological, and optical properties of plasma polymerized furan-2-carbaldehyde thin films

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    The furan-2-carbaldehyde (PPFCD) amorphous polymer thin films, with several thicknesses, were deposited onto glass substrates using a glow discharge of monomer FCD at ordinary room temperature via plasma polymerization technique. The structural, morphological, and optical characteristics of the as synthesised PPFCD amorphous films were studied as a function of temperature via X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), and ultraviolet-visible (UV–Vis) absorption spectroscopy. The amorphous nature of the thin films was ascertained in both as-synthesised and heat treated states using the XRD studies. The SEM micrographs display homogeneous and fracture free surface of PPFCD films and no remarkable variation in the surface morphology of the as synthesised films was detected owing to the heat treatment procedure. However, the EDX, and FTIR analysis represented some structural rearrangement originated from the heat treatment of the PPFCD thin films. The analysis of the UV–Vis absorption spectroscopy revealed that the absorbance of the films depend on the films thickness and the temperature of the heat treatment. The optical band-gaps of PPFCD amorphous films were found to be significantly decreased with the gradual rise in heat treatment temperature

    Overexpression of Na+/Mg2+ exchanger SLC41A1 attenuates pro-survival signaling

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    The Na+/Mg2+ exchanger SLC41A1 (A1), a key component of intracellular Mg homeostasis (IMH), is the major cellular Mg2+ efflux system, and its overexpression decreases [Mg2+]intracellular. IMH plays an important role in the regulation of many cellular processes, including cellular signaling. However, whether the overexpression of A1 and the consequent drop of [Mg2+]i impact on intracellular signaling is unknown. To examine the latter, we utilized dynamic mass redistribution (DMR) assay, PathScan¼ RTK signaling antibody (PRSA) array, confirmatory Western blot (WB) analyses of phosphorylation of kinases selected by PRSA, and mag-fura 2-assisted fast filter spectrometry (FFS). We demonstrate here that the overexpression of A1 quantitatively and qualitatively changes the DMR signal evoked by the application of PAR-1-selective activating peptide and/or by changing [Mg2+]extracellular in HEK293 cells. PRSA profiling of the phosphorylation of important signaling nodes followed by confirmatory WB has revealed that, in HEK293 cells, A1 overexpression significantly attenuates the phosphorylation of Akt/PKB on Thr308 and/or Ser473 and of Erk1/2 on Thr202/Tyr204 in the presence of 0 or 1 mM (physiological) Mg2+ in the bath solution. The latter is also true for SH-SY5Y and HeLa cells. Overexpression of A1 in HEK293 cells significantly lowers [Mg2+]i in the presence of [Mg2+]e = 0 or 1 mM. This correlates with the observed attenuation of prosurvival Akt/PKB – Erk1/2 signaling in these cells. Thus, A1 expression status and [Mg2+]e (and consequently also [Mg2+]i) modulate the complex physiological fingerprint of the cell and influence the activity of kinases involved in anti-apoptotic and, hence, pro-survival events in cells

    Nursing students motivations and satisfaction, Do the motivation and satisfaction of nursing students change during their study years?

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    Background: Study the level of nursing students` motivations and satisfaction may help policy makers to develop training plans to improve graduates skills and commitment. This study was conducted to investigate nursing students' motivations and satisfaction during study years at Ahvaz Jundishapur University of medical sciences. Methods:It was a cross-sectional study to explore 197 nursing students' viewpoints about their fields. A validated and reliable self-made questionnaire was developed and used. Data analysis was carried out by descriptive statistics, analysis of variance (ANOVA) and t-test using SPSS software (version 16). Results: The study findings showed that the most crucial motivation factors to select nursing course were “job security” and “interest in medical science” with means 3.94 and 3.68 respectively. The mean satisfaction score of the nursing students was under average (2.75). There was significant difference between mean satisfaction scores of the first and last year students (respectively, 3.69 vs. 2.90 p=0.0001). Conclusion: Level of nursing students' satisfaction get reduces after university entrance and during study years gradually. Key words: Nursing student, motivation, satisfactio

    Transverse Fluctuations and Their Effects on the Stable Functioning of Semiconductor Devices

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    Semiconductor plasma is often found in chaotic unpredictable motion which shows some anomalous behaviors providing multiple challenges to work with the instabilities in a semiconductor device. Experimental studies have shown that these instabilities give rise to fluctuations and azimuthal non-uniformities, which are usually present in the semiconductor. The energy fluctuations have also been observed in some of the cases. In this paper, we have obtained the fluctuations in velocity field by integrating the linearized governing hydrodynamic equations with RungeKutta method of order four (RK4). Then, we have come up with a mathematical formulation, where these fluctuations can be obtained from a KdV family equation with homotopy-assisted symbolic simulation. We have also obtained the relative velocity between the solitary structures for different parameters. Finally, by giving a detailed explanation of the behavior of semiconductor devices, we can study the usefulness of formulating the plasma waves in the various regime, and predict their characteristics theoretically

    Measuring the occurrence of antibiotics in surface water adjacent to cattle grazing areas using passive samplers

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    A wide variety of antibiotics and other pharmaceuticals are used in livestock production systems and residues passed to the environment, often unmetabolized, after use and excretion. Antibiotic residuesmay be transported frommanure-treated soils via runoff and are also capable of reaching surface and groundwater systems through a variety of pathways. The occurrence and persistence of antibiotics in the environment is a concern due to the potential for ecological effects and proliferation of environmental antibiotic resistance in pathogenic organisms. In the present study, the occurrence and seasonal variation of 24 commonly-used veterinary antibiotics was evaluated in surface water adjacent to several livestock production systems using Polar Organic Chemical Integrative Samplers (POCIS). Uptake rates for all compounds, nine of which have not been previously reported, were measured in the laboratory to permit estimation of changes in the time-weighted average (TWA) antibiotic concentrations during exposure. The antibiotics detected in POCIS extracts included sulfadimethoxine, sulfamethoxazole, trimethoprim, sulfamerazine, sulfadiazine, lincomycin, erythromycin, erythromycin anhydro- and monensin. The maximum TWA concentration belonged to sulfadiazine (25 ng/L) in the August– September sampling period and coincided with the highest number of precipitation events.With the exception of monensin that showed an increase in concentration over the stream path, none of the detected antibiotics were prescribed to livestock at the facility. The detection of antibiotics not prescribed by the facility may be attributable to the environmental persistence of previously used antibiotics, transfer by wind from other nearby livestock production sites or industrial uses, and/or the natural production of some antibiotics

    Targeting androgen receptor activation function-1 with EPI to overcome resistance mechanisms in castration-resistant prostate cancer

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    Acknowledgments The authors thank Kate Watt (University of Aberdeen, Aberdeen, Scotland) for technical support. The authors are also grateful to Country Meadows Senior Men's Golf Charity Classic for financial support of this research. Financial support: This research was supported by grants to MDS from the NCI (2R01CA105304), the Canadian Institutes of Health Research (MOP79308) and the US Army Medical Research and Materiel Command Prostate Cancer Research Program (E81XWH-11-1-0551). Research by IJM’s group was supported by the Chief Scientist’s Office of the Scottish Government (ETM-258 and -382). We are grateful to Country Meadows Senior Men’s Golf Charity Classic for financial support of this research.Peer reviewedPostprin

    Trigliserida Sebagai Faktor Prognosis Untuk Hipertensi Tidak Terkendali Pada Wanita Pasca Menopause Di Kota Bogor, Tahun 2014

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    Further analysis aimed to determine the new cut-off correlation between blood triglyceride levels withuncontrolled hypertension among 888 postmenopausal women from two-year follow up of the cohort studyin Bogor. Uncontrolled hypertension was defined as the average of systolic and diastolic are >140mmHgand >90mmHg consecutively with no underlying diseases and systolic is >130mmHg with co-morbidityat the end of 2-year follow up. The covariate variables included demography, behavior and biologicalfactors. The new triglyceride\u27s cut off was determined by ROC curve with 65% sensitivity and 68%specificity. Data were analyzed with multiple logistic regression. Blood triglyceride level significantlycorrelated with uncontrolled hypertension (p=0.007) after adjusted with LDL, postprandial blood sugarand sodium intake. Triglyceride levels of 108-149mg/dl resulted in OR of 1.54 (95% CI 0.95 to 2.48),150-199mg/dl showed OR of 2.04 (95% CI 1.06 to 3.93) and level of >200 indicated an OR 2.1 (95% CI1.02 to 4.30) compared to normal level (<108mg/dl). Triglyceride level of 108mg/dl is a new cut-off todetermine uncontrolled hypertension in postmenopausal women in the study area. Blood triglyceride\u27slevel can be used as a prognostic factor for hypertensive patients to monitor blood pressure increment
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