Regular Exercise Training as a Principal Non-Pharmacological Method Affects Serum Leptin and Cardiovascular Risk Factors in Men with Metabolic Syndrome

Background and Aim: Regular exercise training is the principal non-pharmacological method for the prevention and treatment of metabolic syndrome or other obesity-related diseases. We investigated the effects of aerobic training on leptin and cardiovascular risk factors in middle-aged men with metabolic syndrome. Methods: Twenty-six sedentary middle-aged males with metabolic syndrome aged 40 ± 5 years were randomly assigned to two groups as exercise (aerobic training, n =13) and control (no training, n =13). The exercise programs were performed 3 days a week for 10 weeks at 55-75% of HRmax. Fasting blood samples were taken before and after the training period for measuring serum leptin and triglyceride (TG), total cholesterol (TC), LDL, and HDL as cardiovascular risk factors. Results: No significant differences were observed between groups concerning anthropometric and clinical markers at baseline (p>0.05). Aerobic intervention resulted in significant decrease in anthropometric markers (abdominal circumference, body mass index, body fat percentage; p < 0.05), serum leptin (p = 0.026), TG (p = 0.001) and HDL (p = 0.032) in exercise group, but significant changes were not found in TC (p = 0.522) and LDL (p = 0.546). There were no changes in all measured variables in the control group. Conclusion: Based on our finding, it seems that regular aerobic exercise is associated with improved serum leptin and cardiovascular function in patients with metabolic syndrome. *Corresponding Author: Mojtaba Eizadi; Email: [email protected] Please cite this article as: Naseri Rad R, Eizadi M. Regular Exercise Training as a Principal Non-Pharmacological Method Affects Serum Leptin and Cardiovascular Risk Factors in Men with Metabolic Syndrome. Arch Med Lab Sci. 2020;6:1-8 (e1). https://doi.org/10.22037/amls.v6.3164

The Participants' viewpoint of continuing medical education courses

Background: Continuing education is one of the most effective methods to empower the employees for challengesthey face on their jobs. Dramatic advances in medicine, rapid cultural and social changes, increasing cost of healthcare, development of diagnostic technology and a transition in the pattern of diseases, highlight the necessity ofcontinuing education in all medical groups. Purpose: To evaluate the effectiveness of continuing medical education (CME) programs in Shahr-Kord MedicalUniversityfrom 1996-2001

Volunteered geographic information in crisis management

During the disaster, rescue groups are responsible for tasks that require different types of information to optimize their activities. Preparation and distribution of information are very sensitive. The acquisition of new data and events such as degraded buildings and injured people in some cases using conventional methods is very difficult. With the advancement of technology, people familiar with social networks and smartphones, people produce and generate large amounts of data. This phenomenon is called Volunteered geographic information. Today, this data collected and shared with sites and social networks for free. This paper pays service that Volunteered geographic information provided to crisis management. Experience has shown that the system cannot work without regard to environmental considerations. The current system of data collection, updating and spatial data infrastructure, cannot consider emergency situations. In particular, companies such as Ushahidi and OSM's activities will be described. This article is based on articles and activities conducted in this field and provides the category and in the end, discussed and determine the factors affecting the performance of them

Effect of Low-level Laser Therapy With Different Locations of Irradiation on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double-Blind Randomized Controlled Trial

Introduction: This double-blind, placebo-controlled, clinical trial aimed to investigate the analgesic efficacy of low-level laser therapy (LLLT) with two different locations, and their comparison, in postoperative endodontic pain (PEP) levels in molars diagnosed with symptomatic irreversible pulpitis.Methods: Seventy-five patients with a molar tooth, diagnosed with symptomatic irreversible pulpitis, were divided into three groups of placebo, buccal only irradiation (BI), and buccal and lingual irradiation (BLI), with 25 cases being in each group. The participants received similar singlevisit nonsurgical endodontic treatments. Then, a sham laser was used in the control group instead of LLLT. Individuals in BI and BLI groups received 80-second irradiation on the buccal surface and 80-second irradiation on each of the buccal and lingual surfaces respectively. A laser with an 808 nm wavelength, power of 100 mW, a fiber diameter of 600 μm, and a dose of 70 J/cm2 was used. PEP was assessed using a 0-100 mm VAS 4, 8, 24, and 48 hours after the treatment.Results: BLI showed a significantly higher reduction of PEP compared to placebo in all time intervals of this study. BLI was significantly more effective than BI 8 hours after the treatment. However, intragroup differences between BLI and BI groups at other time intervals and between BI and placebo groups in all time intervals were not significant. The number of taken analgesics in the BLI group was significantly lower than the placebo group and was on a statistical borderline compared to the BI group.Conclusion: LLLT with BLI was an effective measure as a supplement to oral analgesics in the reduction of PEP compared to the placebo

Serum Folate and Vitamin B12 Levels in Hemodialysis Patients: Is There any Correlation with Plasma Homocysteine Levels?

Introduction: Deficiencies of water soluble vitamins such as folate and vitamin B12 has been reported as etiologic factors of hyperhomocysteinemia. This study was conducted to find whether there is a correlation between serum levels of these vitamins and plasma total homocysteine (tHcy) levels.Material and Methods: 19 hemodialysis subjects were enrolled. The study group comprised 52.6% girls and 47.4% boys aged 80-324 (204.7±78.4) months who were on dialysis from 1.5-153 (42.1±43.3) months ago. All patients were supplemented by folate and 15 cases were received oral vitamin B12.Folate serum levels <1.5 ng/ml were defined as low (deficiency).As for vitamin B12, levels < 120 pg/ml, 120-160 pg/ml were defined as deficient and borderline, respectively. Plasma Hcy levels of 5-15 µmol/L and > 15 µmol/L were defined as normal and hyperhomocysteinemia, respectively. The correlation between the serum levels of vitamins and plasma Hcy levels was checked by the Pearson correlation test and P-values <0.05 and r>0.7 indicated a good (significant) correlation. Results: 13 patients (68.4%) had hyperhomocysteinemia whereas plasma tHcy levels were normal in 6 (31.6%). No patient had folate or vitamin B12 deficiency.There was no correlation between tHcy levels and serum vitamin B12 (P=0.621, r=1) and serum folate levels (P=0.571, r=1).Conclusions: Normal and even high serum levels of folate and vitamin B12 cannot prevent the occurrence of hyperhomocysteinemia in hemodialysis patients. Keywords: Hemodialysis; Folate; Vitamin B12; Homocysteine; Hyperhomocysteinemia.

The absolute chronology of East Chia Sabz: a Pre-Pottery Neolithic site in Western Iran

East Chia Sabz is a PPN site located in the Seimareh Valley, western Iran. 14C dating results indicated that the site was occupied from the early 9th millennium to the early 7th millennium BC. As we have very little information about early Neolithic sites in Iran in comparison with the other regions of the Near and Middle East, the site of East Chia Sabz will provide a new benchmark for investigating the Neolithisation process in Iran. It is important to note that further investigation of Chia Sabz will certainly provide more secure information about how and when the Epipaleolithic transition to the Neolithic started in the region. This paper will present the recent excavations at the site, and then, based on the 14C dates, will discuss the site’s importance in western Iran.Vzhodni Chia Sabz je najdišče, ki je locirano v dolini Seimareh v zahodnem Iranu in datira v obdobje predkeramičnega neolitika. Rezultati radiokarbonskih datacij so pokazali, da je bilo najdišče poseljeno od začetka 9. do začetka 7. tisočletja pr.n.št. Glede na to, da imamo le malo podatkov o zgodnjeneolitskih najdiščih v Iranu v primerjavi z drugimi regijami na Bližnjem in Srednjem vzhodu, bo najdišče Vzhodni Chia Sabz postavilo nova merila za preiskovanje procesa neolitizacije v Iranu. Opozarjamo, da bodo nadaljnje preiskave najdišča Chia Sabz ponudile bolj zanesljive podatke o tem, kako in kdaj se je začel prehod iz epipaleolitika v neolitik v tej regiji. V članku predstavljamo nedavna izkopavanja na najdišču in razpravljamo o pomenu najdišča v zahodnem Iranu na podlagi radiokarbonskih datumov

Investigation of Magnitude and Position of Maximum von Mises Stress in The Cylindrical Contact Problems

In the analysis of contact mechanics problems, determination of stress field in mechanical elements is essential. Between the stress components the von Mises stress is more important, because it is used in the investigation of yield criteria and fatigue fracture of elements. The aim of this study is to present formulas for determining the magnitude and position of maximum von Mises stress. For this purpose, the effect of various material properties, element geometries and loading conditions on these two parameters are investigated. By applying Hertzian contact stress and von Mises relations, the magnitude and position of maximum von Mises stress are determined. The von Mises stress is assumed to be a function of material properties, geometry of the element and loading conditions and finally two formulas are presented for the calculation of the magnitude and position of maximum von Mises stress. The results of these presented formulas are in close agreement with the literature. The error is less than 1% for depth prediction and less than 6% for stress value prediction, which confirms the accuracy of the presented formulas

Attitude Control Optimization of a Virtual Telescope for X-ray Observations

In this paper, a novel approach is investigated for the attitude control of two satellites acting as a virtual telescope. The Virtual Telescope for X-ray Observations (VTXO) is a mission exploiting two 6U-CubeSats operating in precision formation. The goal of the VTXO project is to develop a space-based, X-ray imaging telescope with high angular resolution precision. In this scheme, one CubeSat carries a diffractive lens and the other one carries an imaging device to support a focal length of 100 m. In this mission, the attitude control algorithms are required to keep the two spacecrafts in alignment with the Crab Nebula observations. To meet this goal, the attitude measurements from the gyros and the star trackers are used in an extended Kalman filter, for a robust hybrid controller. Due to limited energy and the requirement of high accuracy, the energy and accuracy of attitude control is optimized for this mission

Surface tension of binary mixtures containing environmentally friendly ionic liquids: Insights from artifcial intelligence

The surface tension (ST) of ionic liquids (ILs) and their accompanying mixtures allows engineers to accurately arrange new processes on the industrial scale. Without any doubt, experimental methods for the specification of the ST of every supposable IL and its mixtures with other compounds would be an arduous job. Also, experimental measurements are effortful and prohibitive; thus, a precise estimation of the property via a dependable method would be greatly desirable. For doing this task, a new modeling method according to artificial neural network (ANN) disciplined by four optimization algorithms, namely teaching�learning-based optimization (TLBO), particle swarm optimization (PSO), genetic algorithm (GA) and imperialist competitive algorithm (ICA), has been suggested to estimate ST of the binary ILs mixtures. For training and testing the applied network, a set of 748 data points of binary ST of IL systems within the temperature range of 283.1�348.15 K was utilized. Furthermore, an outlier analysis was used to discover doubtful data points. Gained values of MSE & R2 were 0.0000007 and 0.993, 0.0000002 and 0.998, 0.0000004 and 0.996 and 0.0000006 and 0.994 for the ICA-ANN, TLBO-ANN, PSO-ANN and GA-ANN, respectively. Results demonstrated that the experimental data and predicted values of the TLBO-ANN model for such target are wholly matched