Management of pregnant women in times of COVID-19 our experience from Kashmir valley

Background: The coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, is a global public health emergency. COVID-19 is a rapidly evolving situation, and there is limited data reporting its impact on pregnant women. Our study aimed to find the symptomatology, clinical courses and outcome of pregnant women with COVID-19 and to assess the vertical transmission potential of COVID-19 in pregnancy.Methods: This prospective observational study was conducted at Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Medical College, Department of Gynaecology and obstetrics, Srinagar from May 2020 to September 2020. All COVID-19 positive pregnant patients admitted in our institution were included in our study.Results: The study included 100 Covid-19 positive pregnant women. Most of them were between 30 to 40 years of age. Median gestational age was 32.8 weeks. Comorbidity was present in 18 of our patients. 7 patients had gestational diabetes and 1 with overt diabetes, 5 were hypertensive, 3 had hypothyroidism, 1 with anti-phospholipid antibody syndrome (APLA) and 1 with asthma.44 patients were primigravidae and 56 were multigravidae. 27 patients delivered preterm and 44 with term pregnancy. 47 had undergone caesarean section and 24 normal vaginal delivery.88% of our patients were asymptomatic for covid-19 disease while as 12 patients had Covid-19 disease symptoms. The main complaints reported by patients related to covid-19 disease was mild dry cough and fever (9%). Two patients developed severe covid-19 pneumonia with ARDS and were put on ventilator, expired after 20 days of illness. All neonates were subjected to RT-PCR with none producing positive results.Conclusions: Appropriate and timely management of Covid-19 positive pregnant women is a principle for safe motherhood and healthy offspring in times of global pandemic. The present data do not suggest an increased risk of severe disease among pregnant women. We encourage the breast feeding immediately after delivery as benefits overweigh any potential risks of virus transmission if any

Sales Management Portal

The objective of this project is to develop a sales portal which would be used as a platform for selling the courses of Han Academy Naperville to the parents and prospective students in the community. The parent and guardians of the students can select any specific course which is available in school portal to find out detailed information, the portal will log enquires and contact information. Then it should be very easy for parents to select the courses and register the courses they can also fill out all required details and complete the process on just a few clicks. The course portal system should automatically synchronize with existing course management portal of \u27Han Academy Naperville\u27. This course management portal should be developed using an open source technology like PHP and Moodle. The main purpose is to create an interest among students so their parents or guardians can choose according to the students’ academic standings. The sales portal will be focused on managing pipelines along with marketing tools and various learning options which will be directly connected and displayed on the course portal. The variety of options available at the portal will encourage parents/guardians to help the student be successful in school

Socio-demographic determinants of pregnancy induced hypertension

Background: Pregnancy induced hypertension is a major health problem affecting the maternal and neonatal health, this serious obstetric problem occurs in women with pre-existing primary or secondary hypertension or women who are not having hypertension before pregnancy.Methods: A cross-sectional study was carried out among the women suffering from pregnancy induced hypertension, admitted in the gynaecology wards of Lal-Ded hospital, Srinagar from May 2021 to July 2021. A total of 100 sample patients were taken and data was collected using structured questionnaire. Data was analyzed by using SPSS 16.0.Results: Women suffering from PIH were having the mean age of 28 years with the mean gestation period being 36 weeks+6 days. Their mean systolic blood pressure was 150 mmHg and mean diastolic blood pressure was 98 mmHg. Out of 100 women, 75% were multigravida and 25% were primigravida and 40% were having a history of hypertension before pregnancy. Only 48% had a history of PIH in previous pregnancies while 52% had no such history. In 14% of PIH patients, there was an associated systemic disease. Out of 100, 48% belonged to rural areas, 15% were living in urban areas while 37% resided in semi-urban district. 46% of the patients were illiterate while 54% were educated, be it primary, secondary or higher level. Only 8% were employed while the rest were house wives. 11% had not been to a gynaecologist during their pregnancy while 13% had one visit done, 30% two and 46% had three or more antenatal visits. 67% had a history of hypertension among blood relatives.Conclusions: Pregnancy induced hypertension and socio-demographic determinants like the age of mother, blood pressure, history of hypertensive disorders in blood relatives,do show correlation Among these, history of PIH and chronic hypertensive disorders in blood relatives and high BP seemed to be the strongest risk factors among these 100 women

The Macroeconomic Impacts of Entitlements

The worries expressed by Alan Greenspan that the long run economic growth of the United States will fade away due to increasing burden of entitlements motivated us to empirically investigate the impact of entitlements of key macroeconomic variables. To examine this contemporary issue, we estimate a vector error-correction model to analyze the impact of entitlements on the price level, real output, and the long-term interest rate. The results show that a shock to entitlements leads to decrease in output and lends support to the assertion made by Alan Greenspan. Several robustness checks verify that the results remain unchanged qualitatively

Male Obesity and Reproductive Health

Obesity has reached epidemic proportions globally, and all this evidence suggests that the situation is likely to get worse ahead. A combination of an increasingly sedentary lifestyle and unfavorable diet in the western world has resulted in increasing numbers of overweight and obese children and adults. According to the WHO, approximately 1.6 billion adults were classed as being overweight and 400 million adults were obese in 2005. Also gaining attention is the reported decline in semen quality and male reproductive potential over the past 50 years. Surprisingly, such decreases have not been reported in regions where obesity is less prevalent. Since this decline in fertility has occurred in parallel with increasing rates of obesity, the possibility that obesity is a cause of male infertility and reduced fecundity should be addressed. Effects of obesity on female fertility have been studied extensively. Weight loss in anovulatory women restores fertility and increases the likelihood of ovulation and conception. In contrast to the extensive knowledge of the effects of obesity on female fertility, male factor infertility as a result of obesity has been overlooked, even after the discovery of a threefold increase in the incidence of obesity in patients with male factor infertility, demanding the concern over m ale obesity with respect to infertility

Serum malondialdehyde and adiponectin in albuminuric kidney disease patients

Background: Diabetes, hypertension, oxidative stress, obesity, adipocytokine dysfunction, and dyslipidemia are causative factors in development of Chronic Kidney Disease (CKD). Adiponectin secreted from adipose tissue, has Reno protective effect against development of albuminuria in animal studies. The previous studies investigated the relationship between serum adiponectin level and urinary albuminuria in kidney disease patients, but the results are conflicting.Methods: The pre diagnosed kidney disease patients were divided into microalbuminuria and macroalbuminuria groups, while control subjects were called as normoal buminuria group. The pre diagnosed adult kidney disease patients of both genders with age matching control subjects with no known comorbidity were included in the study. Whereas pregnant female patients and the patients with comorbidity were excluded from the study. The demographic data and the anthropometric data of control and kidney patients were recorded. The blood was analyzed for Glycosylated Hemoglobin (HbA1c), electrolytes, glucose, calcium, total protein, albumin, urea, creatinine adiponectin and malondialdehyde. The Urine was analyzed for Creatinine and albuminuria. The glomerular filtration rate was estimated.Results: The blood pressure, blood urea, creatinine, glycated hemoglobin, malondialdehyde, adiponectin levels were higher in albuminuric kidney patients as compared to normal control subjects. The mean glomerular filtration rate was lowest in macroalbuminuric patients as compared to micro and normoalbuminuric patients. The serum adiponectin and serum malondialdehyde both showed positive correlation with serum creatinine, and with albuminuria/urinary creatinine ratio.Conclusions: The study concludes that, positive correlation of serum malondialdehyde with adiponectin and albuminuria

Grade Classification for Water Chestnuts, their Dimensional Properties and Correlation Analysis

66-70The aim of the present study was to devise the grade classification for whole water chestnuts and kernels and to determine their dimensional properties. The data generated during the study will help in designing post-harvest handling equipments for water chestnuts in future. The mean values of length, width and thickness for whole water chestnuts ranged between ≤ 30 - > 45mm; ≤ 23- > 35mm and ≤ 9 - >18mm from grade I (very small) to grade V (very large) respectively, whereas, the corresponding values for whole water chestnut kernels ranged between ≤ 18 - > 36 mm; ≤ 13- > 22mm and ≤ 7 - > 16 mm from grade I to grade V respectively.  For all the five devised grades, the mean values of derived dimensional properties were significantly (p<0.05) different in both whole water chestnuts as well as in kernels. Correlation analysis revealed significant (p<0.05) positive correlation among all the dimensional properties of whole water chestnuts. In case of whole water chestnut kernels, all the dimensional properties showed significant positive correlation with each other, except sphericity and aspect ratio, which showed non-significant positive and negative correlations with all the dimensional properties respectively

Video-GroundingDINO: Towards Open-Vocabulary Spatio-Temporal Video Grounding

Video grounding aims to localize a spatio-temporal section in a video corresponding to an input text query. This paper addresses a critical limitation in current video grounding methodologies by introducing an Open-Vocabulary Spatio-Temporal Video Grounding task. Unlike prevalent closed-set approaches that struggle with open-vocabulary scenarios due to limited training data and predefined vocabularies, our model leverages pre-trained representations from foundational spatial grounding models. This empowers it to effectively bridge the semantic gap between natural language and diverse visual content, achieving strong performance in closed-set and open-vocabulary settings. Our contributions include a novel spatio-temporal video grounding model, surpassing state-of-the-art results in closed-set evaluations on multiple datasets and demonstrating superior performance in open-vocabulary scenarios. Notably, the proposed model outperforms state-of-the-art methods in closed-set settings on VidSTG (Declarative and Interrogative) and HC-STVG (V1 and V2) datasets. Furthermore, in open-vocabulary evaluations on HC-STVG V1 and YouCook-Interactions, our model surpasses the recent best-performing models by $4.88$ m_vIoU and $1.83\%$ accuracy, demonstrating its efficacy in handling diverse linguistic and visual concepts for improved video understanding. Our codes will be publicly released