Cruise Report 71-S-8: Crab

(PDF contains 3 pages.

Ocean shrimp report 1972 season

California's 1972 ocean shrimp landings totaled 2,488,683 pounds, a decrease of 585,857 pounds from the 1971 season when 3,074,540 pounds were landed. The decrease resulted primarily from the failure of the vessels to reach the quotas in Areas A, B-1 and B-2. (18pp.

Phosphoproteins associated with cyclic nucleotide stimulation of ciliary motility in Paramecium

Permeabilized, MgATP-reactivated cells of Paramecium (models) respond to cyclic AMP and cyclic GMP by increasing forward swimming speed. In association with the motile response, cyclic AMP and 8-bromo-cyclic GMP (8-Br-cyclic GMP) stimulated protein phosphorylation. Cyclic AMP addition to permeabilized cells reproducibly stimulated the phosphorylation of 10 proteins, ranging in molecular weight from 15 to 110K (K = 10^3 M_r). 8-Br-cyclic GMP, which selectively activates the cyclic GMP-dependent protein kinase of Paramecium, stimulated the phosphorylation of a subset of the proteins phosphorylated by cyclic AMP. Ca^(2+) addition caused backward swimming and stimulated the phosphorylation of four substrates, including a 25K target that may also be phosphorylated in response to cyclic nucleotide addition. Ba^(2+) and Sr^(2+) also induced backward swimming, but did not cause detectable phosphorylation. To identify ciliary targets of cyclic nucleotide-dependent protein kinase activity, permeabilized cells were deciliated following reactivation of motility with Mg-[y-^(32)P]ATP in the presence or absence of cyclic nucleotide. Soluble proteins of the deciliation supernatant were enriched in 15 cyclic AMP-stimulated phosphoproteins, ranging in molecular weight from 15 to 95K. Most of the ciliary substrates were axonemal and could be released by high salt solution. A 29K protein that copurified in sucrose gradients with the 22S dynein, and a high molecular weight protein (greater than 300K) in the 19 S region were phosphorylated when cyclic AMP was added to permeabilized, motile cells. These data suggest that regulation of ciliary motility by cyclic AMP may include phosphorylation of dynein-associated proteins

The Poetry of Thomas Merton

There is a need, then, for a study of Merton\u27s poetry as a whole--a study based not on the poetry as a result of his poetic theory but on the poetry primarily as poetry, and which would include his last three volumes. This paper, therefore, will be a survey of representative samplings from each volume of Merton\u27s poetry, and will take into account the differences and similarities between his early and later periods. It will attempt to discover and illustrate the most significant aspects of the development of Merton\u27s philosophy and poetics, as revealed by the poetry itself and by the critical opinion about it. It of necessity will be selective and somewhat general

Cruise Report 71-S-2: Prawns

(PDF contains 4 pages.

Ocean shrimp report: 1971 Season; Fifteenth Annual Shrimp Report

California's 1971 ocean shrimp landings totaled 3,074,540 pounds, a decrease of nearly a million pounds from 1970. The decrease resulted primarily from the failure of Area A vessels to reach the quota, and the lack of significant landings in the remaining permit areas

Cruise Report 70-S-8: Crab

(PDF contains 3 pages.

Cruise Report 69-S-7: Crab

(PDF contains 2 pages

Snap shots

Snap Shots is a creation story, an origin story, founded from an old cardboard box of photographs. While it is not about adoption, it is written through the eyes of an orphan, a foster child, an adopted person, a mother, a wife, a woman. It is a work of honesty, of courage, of pain, of love, and of acceptance. Inspired and influenced by the work of Lawrence Sutin, specifically A Postcard Memoir, this work is the culmination of an intense and exciting dive into the genre of creative nonfiction. Unlike Sutin\u27s collection of found objects over years of random scouring of antiques stores, Snap Shots is literally, and metaphorically, a photo album of me, my people (as much as anyone can have their own people), and profound parts of my life. An album that is not stagnate and placed on a shelf to become dusty and never opened again, but one that goes through change over time, with the photos and stories being rearranged, replaced, renewed. While the book is bound, its intention is to never really be done. As I continue my career and life as a writer, I hope to always return to these photos and this life and, many years from now when I am a very old woman, still look fondly at these photos and read these stories, smile, and learn

A Path to Implement Precision Child Health Cardiovascular Medicine.

Congenital heart defects (CHDs) affect approximately 1% of live births and are a major source of childhood morbidity and mortality even in countries with advanced healthcare systems. Along with phenotypic heterogeneity, the underlying etiology of CHDs is multifactorial, involving genetic, epigenetic, and/or environmental contributors. Clear dissection of the underlying mechanism is a powerful step to establish individualized therapies. However, the majority of CHDs are yet to be clearly diagnosed for the underlying genetic and environmental factors, and even less with effective therapies. Although the survival rate for CHDs is steadily improving, there is still a significant unmet need for refining diagnostic precision and establishing targeted therapies to optimize life quality and to minimize future complications. In particular, proper identification of disease associated genetic variants in humans has been challenging, and this greatly impedes our ability to delineate gene-environment interactions that contribute to the pathogenesis of CHDs. Implementing a systematic multileveled approach can establish a continuum from phenotypic characterization in the clinic to molecular dissection using combined next-generation sequencing platforms and validation studies in suitable models at the bench. Key elements necessary to advance the field are: first, proper delineation of the phenotypic spectrum of CHDs; second, defining the molecular genotype/phenotype by combining whole-exome sequencing and transcriptome analysis; third, integration of phenotypic, genotypic, and molecular datasets to identify molecular network contributing to CHDs; fourth, generation of relevant disease models and multileveled experimental investigations. In order to achieve all these goals, access to high-quality biological specimens from well-defined patient cohorts is a crucial step. Therefore, establishing a CHD BioCore is an essential infrastructure and a critical step on the path toward precision child health cardiovascular medicine