1,180 research outputs found

    Mejoramiento en la prestación de los servicios de seguridad ciudadana por parte de la Municipalidad Provincial del Cusco

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    La oportunidad de mejora continua, debe ser la primera opción que todo gestor público debe optar. Así, en un sinfín de procesos administrativos por modernizar en nuestras localidades, la materialización de iniciativas públicas, surgidas desde la academia, que destraben el desarrollo de espacios ciudadanos comunes, deben ser prioritarios. Corresponde a los gobiernos locales, como función específica y exclusiva, organizar y gestionar el servicio de seguridad ciudadana, ello está dispuesto en la Ley Orgánica de Municipalidades, Ley No 27972 y la Ley del Sistema Nacional de Seguridad Ciudadana, Ley N° 27933. De este modo, este trabajo presenta una propuesta de agilizar, profesionalizar y modernizar la provisión del servicio de seguridad ciudadana, que está a cargo de la Municipalidad Provincial del Cusco. Para responder a la necesidad de solucionar una inadecuada prestación del servicio de seguridad pública en el gobierno provincial del Cusco, proponemos, principalmente dos objetivos, el primero que llevará per se, a mejorar el proceso de selección de los recursos humanos, que estará a cargo de la provisión del servicio de seguridad ciudadana y el segundo, fortalecerá la articulación del trabajo conjunto, que desarrollará el personal de seguridad ciudadana, junto a la Policía Nacional del Perú. La principal motivación que encontramos al proponer este modelo de prestación de servicio, en favor de los ciudadanos, radica en las personas que actualmente vienen laborando en la Subgerencia de Seguridad Ciudadana y Servicios Municipales, pues cuentan con experiencia en la materia y tienen conocimiento de la localidad. Por ello, uno de nuestros planteamientos es que sea el actual personal el que, luego de un proceso de asistencia técnica y capacitación, estén calificados para asumir la nueva configuración del servicio de seguridad ciudadana. Dentro de la estrategia del presupuesto por resultados, se ha diseñado el Programa Presupuestal 030: “Reducción de delitos y faltas que afectan a la seguridad ciudadana”, programa presupuestal que ha previsto acciones y lineamientos que de manera integral y articulada, buscan dar soluciones a los problemas de la inseguridad ciudadana, siendo una unidad de programación presupuestaria, permite a los municipios, disponer y orientar recursos, para que los servicios de seguridad ciudadana, tengan efectos favorables a favor de los ciudadanos, en la respectiva jurisdicción del gobierno local. Por lo tanto, es importante la modernización del enfoque de trabajo, respecto a la labor municipal en materia de seguridad ciudadana, pues de materializar esta propuesta, será la responsable de actualizar y profesionalizar al personal que labora día a día en la seguridad de las personas. Por último, es importante señalar que el presente trabajo cuenta con viabilidad política, técnica, social, presupuestal y operativa, pues el abordaje de seguridad ciudadana es una prioridad para el país, expresada en la Visión del País al 2050. Así mismo, la Ley del Sistema Nacional de Seguridad Ciudadana (No 27933) busca garantizar el irrestricto uso de las libertades y derechos de las personas para garantizar su tranquilidad, seguridad y paz de los ciudadanos en el territorio nacional

    Seizure burden in severe earlyâ life epilepsy: Perspectives from parents

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    ObjectivesSeizure burden is typically measured by seizure frequency yet it entails more than seizure counts, especially for people with severe epilepsies and their caregivers. We aimed to characterize the multiâ faceted nature of seizure burden in young people and their parents who are living with severe earlyâ life epilepsies.MethodsA oneâ day workshop and a series of teleconferences were held with parents of children with severe, refractory epilepsy of earlyâ life origin and providers for children with epilepsy. The workshop sessions were structured as focus groups and aimed to identify components of seizure burden and their impact from the perspective of parents and providers. Data were gathered, organized, and refined during the workshop using an iterative 4â step process that drew upon grounded theory.ResultsThree primary components of seizure burden were identified: frequency, severity, and unpredictability, which was as important if not more important at times than frequency and severity. Caregivers noted that the impacts of seizures were experienced as acuteâ immediate consequences, longerâ term consequences, and as chronic effects that develop and evolve over time. The severity of the child’s neurological and medical status as well as where in the disease journey a family was represented additional contextual factors that influenced the experience of seizure burden.SignificancePatientâ reported and patientâ centered outcomes are increasingly incorporated into the evaluation of treatment effectiveness. Without understanding how the disease creates burden for the patient (or family), it is difficult to know how to assess the impact of treatment. Our preliminary findings indicate seizure burden is a complex construct and unpredictability can be as important as frequency and severity.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149509/1/epi412319_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149509/2/epi412319.pd

    Understanding young people's transitions in university halls through space and time

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    This article contributes to the theoretical discussion about young people's transitions through space and time. Space and time are complex overarching concepts that have creative potential in deepening understanding of transition. The focus of this research is young people's experiences of communal living in university halls. It is argued that particular space-time concepts draw attention to different facets of experience and in combination deepen the understanding of young people's individual and collective transitions. The focus of the article is the uses of the space-time concepts 'routine', 'representation', 'rhythm' and 'ritual' to research young people's experiences. The article draws on research findings from two studies in the North of England. © 2010 SAGE Publications

    ANKK1, TTC12, and NCAM1 polymorphisms and heroin dependence: importance of considering drug exposure

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    Context: The genetic contribution to liability for opioid dependence is well established; identification of the responsible genes has proved challenging. Objective: To examine association of 1430 candidate gene single-nucleotide polymorphisms (SNPs)with heroin dependence, reporting here only the 71 SNPs in the chromosome 11 gene cluster (NCAM1, TTC12, ANKK1, DRD2) that include the strongest observed associations. Design: Case-control genetic association study that included 2 control groups (lacking an established optimal control group). Setting: Semistructured psychiatric interviews. Participants: A total of 1459 Australian cases ascertained from opioid replacement therapy clinics, 531 neighborhood controls ascertained from economically disadvantaged areas near opioid replacement therapy clinics, and 1495 unrelated Australian Twin Registry controls not dependent on alcohol or illicit drugs selected from a twin and family sample. Main Outcome Measure: Lifetime heroin dependence. Results: Comparison of cases with Australian Twin Registry controls found minimal evidence of association for all chromosome 11 cluster SNPs (P≥.01); a similar comparison with neighborhood controls revealed greater differences (P≥1.8×10-4). Comparing cases (n=1459) with the subgroup of neighborhood controls not dependent on illicit drugs (n=340), 3 SNPs were significantly associated (correcting for multiple testing): ANKK1 SNP rs877138 (most strongly associated; odds ratio=1.59; 95% CI, 1.32-1.92; P=9.7×10-7), ANKK1 SNP rs4938013, and TTC12 SNP rs7130431. A similar pattern of association was observed when comparing illicit drug-dependent (n=191) and nondependent (n=340) neighborhood controls, suggesting that liability likely extends to nonopioid illicit drug dependence. Aggregate heroin dependence risk associated with 2 SNPs, rs877138 and rs4492854 (located in NCAM1), varied more than 4-fold (P=2.7×10-9 for the risk-associated linear trend). Conclusions: Our results provide further evidence of association for chromosome 11 gene cluster SNPs with substance dependence, including extension of liability to illicit drug dependence. Our findings highlight the necessity of considering drug exposure history when selecting control groups for genetic investigations of illicit drug dependence

    A large-scale genome-wide association study meta-analysis of cannabis use disorder

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    BACKGROUND: Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50-70%) and is associated with negative outcomes, including increased risk of psychopathology. The aim of the study was to conduct a large genome-wide association study (GWAS) to identify novel genetic variants associated with cannabis use disorder. METHODS: To conduct this GWAS meta-analysis of cannabis use disorder and identify associations with genetic loci, we used samples from the Psychiatric Genomics Consortium Substance Use Disorders working group, iPSYCH, and deCODE (20 916 case samples, 363 116 control samples in total), contrasting cannabis use disorder cases with controls. To examine the genetic overlap between cannabis use disorder and 22 traits of interest (chosen because of previously published phenotypic correlations [eg, psychiatric disorders] or hypothesised associations [eg, chronotype] with cannabis use disorder), we used linkage disequilibrium score regression to calculate genetic correlations. FINDINGS: We identified two genome-wide significant loci: a novel chromosome 7 locus (FOXP2, lead single-nucleotide polymorphism [SNP] rs7783012; odds ratio [OR] 1·11, 95% CI 1·07-1·15, p=1·84 × 10 INTERPRETATION: These findings support the theory that cannabis use disorder has shared genetic liability with other psychopathology, and there is a distinction between genetic liability to cannabis use and cannabis use disorder. FUNDING: National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; National Institute on Drug Abuse; Center for Genomics and Personalized Medicine and the Centre for Integrative Sequencing; The European Commission, Horizon 2020; National Institute of Child Health and Human Development; Health Research Council of New Zealand; National Institute on Aging; Wellcome Trust Case Control Consortium; UK Research and Innovation Medical Research Council (UKRI MRC); The Brain & Behavior Research Foundation; National Institute on Deafness and Other Communication Disorders; Substance Abuse and Mental Health Services Administration (SAMHSA); National Institute of Biomedical Imaging and Bioengineering; National Health and Medical Research Council (NHMRC) Australia; Tobacco-Related Disease Research Program of the University of California; Families for Borderline Personality Disorder Research (Beth and Rob Elliott) 2018 NARSAD Young Investigator Grant; The National Child Health Research Foundation (Cure Kids); The Canterbury Medical Research Foundation; The New Zealand Lottery Grants Board; The University of Otago; The Carney Centre for Pharmacogenomics; The James Hume Bequest Fund; National Institutes of Health: Genes, Environment and Health Initiative; National Institutes of Health; National Cancer Institute; The William T Grant Foundation; Australian Research Council; The Virginia Tobacco Settlement Foundation; The VISN 1 and VISN 4 Mental Illness Research, Education, and Clinical Centers of the US Department of Veterans Affairs; The 5th Framework Programme (FP-5) GenomEUtwin Project; The Lundbeck Foundation; NIH-funded Shared Instrumentation Grant S10RR025141; Clinical Translational Sciences Award grants; National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences

    Creating and Supporting a Mixed Methods Health Services Research Team

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    Objective. To use the experience from a health services research evaluation to provide guidance in team development for mixed methods research
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