Interactions between teachers and students in four co -taught, inclusive, middle school classrooms

Co-teaching in inclusive, content classrooms is becoming increasingly more popular as schools work toward the inclusion of significantly more students with special learning needs in the general education environment. Inherent in every classroom environment is the expectation of teacher-student interactions. It is often the relationship between the teacher and the student that provides opportunities for student achievement and success. The daily interactions that occur between teachers and their students set the tone for the successes and failures that may be realized as a result. The purpose of this study, therefore, is to explore and identify both the context and frequency of interactions that occur between teachers and their students in inclusive, co-taught classrooms in four middle schools in southern West Virginia.;Case study design was used for the study. Both within-case and cross-case analysis were constructed from data that was collected from interviews of co-teacher pairs (both individual and in pairs), observations of co-taught classes, and frequency tabulations of the observed interactions between teachers and their students during instruction. Transcripts from each interview and field notes were prepared and coded for the case studies that were written. In-case and cross-case analysis revealed multiple findings specific to both the current and future practice of co-teaching as a means of delivering instruction to students with special learning needs in inclusive, content classrooms. Additionally, recommendations for future research are suggested

Inferring kinetic parameters of oscillatory gene regulation from single cell time-series data

This work was supported by a Wellcome Trust Four-Year PhD Studentship in Basic Science to J.B. (219992/Z/19/Z) and a Wellcome Trust Senior Research Fellowship to N.P. (090868/Z/09/Z). C.M. was supported by a Sir Henry Wellcome Fellowship (103986/Z/14/Z) and University of Manchester Presidential Fellowship. M.R.’s work was supported by a Wellcome Trust Investigator Award (204832/B/16/Z).Gene expression dynamics, such as stochastic oscillations and aperiodic fluctuations, have been associated with cell fate changes in multiple contexts, including development and cancer. Single cell live imaging of protein expression with endogenous reporters is widely used to observe such gene expression dynamics. However, the experimental investigation of regulatory mechanisms underlying the observed dynamics is challenging, since these mechanisms include complex interactions of multiple processes, including transcription, translation and protein degradation. Here, we present a Bayesian method to infer kinetic parameters of oscillatory gene expression regulation using an auto-negative feedback motif with delay. Specifically, we use a delay-adapted nonlinear Kalman filter within a Metropolis-adjusted Langevin algorithm to identify posterior probability distributions. Our method can be applied to time-series data on gene expression from single cells and is able to infer multiple parameters simultaneously. We apply it to published data on murine neural progenitor cells and show that it outperforms alternative methods. We further analyse how parameter uncertainty depends on the duration and time resolution of an imaging experiment, to make experimental design recommendations. This work demonstrates the utility of parameter inference on time course data from single cells and enables new studies on cell fate changes and population heterogeneity.Publisher PDFPeer reviewe

Alternative Nonvolatile Residue Analysis with Contaminant Identification Project

Cleanliness verification is required in numerous industries including spaceflight ground support, electronics, medical and aerospace. Currently at KSC requirement for cleanliness verification use solvents that environmentally unfriendly. This goal of this project is to produce an alternative cleanliness verification technique that is both environmentally friendly and more cost effective

The Ursinus Weekly, May 26, 1947

Dr. T. A. Distler\u27s speech to highlight seventy-seventh annual commencement • Negro recital ends varied Y programs presented in \u2746-\u2747 • WAA names M. Bosler, H. Anderson, E. Moyer as top junior athletes • Athletic Committee chairman addresses letter winners at Varsity Club banquet • Alumni form Washington unit • Gym to be completed within three months; Construction has begun • Hobo hop attracts enthusiastic crowd • Lantern will include increased material • Holiday runs Pennsylvania-Dutch article • A. Ivins chosen Rosicrucian president at final meeting • K. Kron voted pre-med president • Students hear Romeo and Juliet • M. Sare to head Alpha Psi; Six new members initiated • Debating Club elects officers; Dorothy Dean chosen president • Campus briefs: French Club banquet; Men\u27s May pageant • Students may observe unique bio specimens • Commendation • On sports and bus-rides • At the Library • Alumni-Society notes • Juniata rips Bears; Five miscues cost Landes pitching win • Tennis team trounces tribe racquetmen, 8-1; Loses to Swarthmore • Albright cindermen swamped, 79 1/2-46 1/2; Gurzynski crew nabs ten first places • Owlettes crush Bear coeds in return net engagement • Muhlenberg game cancelled • Kennedy stars again • New grid mentor addresses large group of candidates • Erma Keyes one-hitter tops Garnet for fifth straight • Bearette golfers finish season • Cricket team stunned by Fords in match at victors\u27 grounds • Final examination schedule: Spring term, 1947https://digitalcommons.ursinus.edu/weekly/3122/thumbnail.jp

Cryogenic Insulation Standard Data and Methodologies Project

Extending some recent developments in the area of technical consensus standards for cryogenic thermal insulation systems, a preliminary Inter-Laboratory Study of foam insulation materials was performed by NASA Kennedy Space Center and LeTourneau University. The initial focus was ambient pressure cryogenic boil off testing using the Cryostat-400 flat-plate instrument. Completion of a test facility at LETU has enabled direct, comparative testing, using identical cryostat instruments and methods, and the production of standard thermal data sets for a number of materials under sub-ambient conditions. The two sets of measurements were analyzed and indicate there is reasonable agreement between the two laboratories. Based on cryogenic boiloff calorimetry, new equipment and methods for testing thermal insulation systems have been successfully developed. These boiloff instruments (or cryostats) include both flat plate and cylindrical models and are applicable to a wide range of different materials under a wide range of test conditions. Test measurements are generally made at large temperature difference (boundary temperatures of 293 K and 78 K are typical) and include the full vacuum pressure range. Results are generally reported in effective thermal conductivity (ke) and mean heat flux (q) through the insulation system. The new cryostat instruments provide an effective and reliable way to characterize the thermal performance of materials under subambient conditions. Proven in through thousands of tests of hundreds of material systems, they have supported a wide range of aerospace, industry, and research projects. Boiloff testing technology is not just for cryogenic testing but is a cost effective, field-representative methodology to test any material or system for applications at sub-ambient temperatures. This technology, when adequately coupled with a technical standards basis, can provide a cost-effective, field-representative methodology to test any material or system for applications at sub-ambient to cryogenic temperatures. A growing need for energy efficiency and cryogenic applications is creating a worldwide demand for improved thermal insulation systems for low temperatures. The need for thermal characterization of these systems and materials raises a corresponding need for insulation test standards and thermal data targeted for cryogenic-vacuum applications. Such standards have a strong correlation to energy, transportation, and environment and the advancement of new materials technologies in these areas. In conjunction with this project, two new standards on cryogenic insulation were recently published by ASTM International: C1774 and C740. Following the requirements of NPR 7120.10, Technical Standards for NASA Programs and Projects, the appropriate information in this report can be provided to the NASA Chief Engineer as input for NASA's annual report to NIST, as required by OMB Circular No. A-119, describing NASA's use of voluntary consensus standards and participation in the development of voluntary consensus standards and bodies

Self Healing Coating/Film Project

Kennedy Space Center (KSC) has been developing self healing materials and technologies. This project seeks to further develop self healing functionality in thin films for applications such as corrosion protective coatings, inflatable structures, space suit materials, and electrical wire insulation

Sequential and additive expression of miR-9 precursors control timing of neurogenesis

This work was supported by a Wellcome Trust Senior Research Fellowship (090868/Z/09/Z) and a Wellcome Trust Investigator Award (224394/Z/21/Z) to N.P. and a Medical Research Council Career Development Award to C.S.M. (MR/V032534/1). J.B. was supported by a Wellcome Trust Four-Year PhD Studentship in Basic Science (219992/Z/19/Z). Open Access funding provided by The University of Manchester.MicroRNAs (miRs) have an important role in tuning dynamic gene expression. However, the mechanism by which they are quantitatively controlled is unknown. We show that the amount of mature miR-9, a key regulator of neuronal development, increases during zebrafish neurogenesis in a sharp stepwise manner. We characterize the spatiotemporal profile of seven distinct microRNA primary transcripts (pri-mir)-9s that produce the same mature miR-9 and show that they are sequentially expressed during hindbrain neurogenesis. Expression of late-onset pri-mir-9-1 is added on to, rather than replacing, the expression of early onset pri-mir-9-4 and -9-5 in single cells. CRISPR/Cas9 mutation of the late-onset pri-mir-9-1 prevents the developmental increase of mature miR-9, reduces late neuronal differentiation and fails to downregulate Her6 at late stages. Mathematical modelling shows that an adaptive network containing Her6 is insensitive to linear increases in miR-9 but responds to stepwise increases of miR-9. We suggest that a sharp stepwise increase of mature miR-9 is created by sequential and additive temporal activation of distinct loci. This may be a strategy to overcome adaptation and facilitate a transition of Her6 to a new dynamic regime or steady state.Publisher PDFPeer reviewe

The Ursinus Weekly, April 18, 1949

Council adopts petitions for \u2749 coed elections • Junior men to elect annual prom queen • Black-faced belles plan initial debut for minstrel frolic • Organizations seek support of students in worthy projects • Y commission lists letters, trip, talk in year\u27s activities • Sororities plan party for frosh; Movie, social to highlight affair • FTA elects Heist to presidency for \u2749-\u2750 schedule of activities • What do you demand of your ideal man? • Bruins drop 4-3 decision in ten inning ball game • Five sports events fill week\u27s roster • Sixteen get awards for winter sports • Students find appeal in Curtain Club actshttps://digitalcommons.ursinus.edu/weekly/1614/thumbnail.jp