Poetry As Praxis: An Exploration Of Poetry Discourse As Qualitative Inquiry

To capture the essence of an experience, poetry as research may manifest itself in two ways: (i) creating a research poem from existing data, often transcripts, or (ii) using participants\u27 poetry as a data-set for harvesting patterns and themes. This research focuses on the second form of poetic inquiry as a means of praxis by using the poetry of inservice teachers, preservice teachers, and elementary students to discover themes in regard to the teaching and learning process. As literacy teacher educators, creating praxis (moving from the theoretical to the practical) remains the ultimate goal of teaching and learning experiences. We gathered poems as data-sets in order to explore the possible benefits and limitations of poetic inquiry. As we approached the notion of poetry as a form of inquiry, we probed whether this art-based inquiry might also equate educational praxis. After considering several poetry data-sets, this research provides evidence of possible benefits related to the praxis that poetry as discourse and artistic inquiry affords, and presents the caveats of the research by identifying possible limitations

Unmasking Mean Girls

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Immunization with Recombinant V10 Protects Cynomolgus Macaques from Lethal Pneumonic Plague▿

Vaccine and therapeutic strategies that prevent infections with Yersinia pestis have been sought for over a century. Immunization with live attenuated (nonpigmented) strains and immunization with subunit vaccines containing recombinant low-calcium-response V antigen (rLcrV) and recombinant F1 (rF1) antigens are considered effective in animal models. Current antiplague subunit vaccines in development for utilization in humans contain both antigens, either as equal concentrations of the two components (rF1 plus rLcrV) or as a fusion protein (rF1-rLcrV). Here, we show that immunization with either purified rLcrV (a protein at the tip of type III needles) or a variant of this protein, recombinant V10 (rV10) (lacking amino acid residues 271 to 300), alone or in combination with rF1, prevented pneumonic lesions and disease pathogenesis. In addition, passive immunization studies showed that specific antibodies of macaques immunized with rLcrV, rV10, or rF1, either alone or in combination, conferred protection against bubonic plague challenge in mice. Finally, we found that when we compared the reactivities of anti-rLcrV and anti-rV10 immune sera from cynomolgus macaques, BALB/c mice, and brown Norway rats with LcrV-derived peptides, rV10, but not rLcrV immune sera, lacked antibodies recognizing linear LcrV oligopeptides

Natural History of Marburg Virus Infection to Support Medical Countermeasure Development

The Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services, recognizes that the evaluation of medical countermeasures under the Animal Rule requires well-characterized and reproducible animal models that are likely to be predictive of clinical benefit. Marburg virus (MARV), one of two members of the genus Marburgvirus, is characterized by a hemorrhagic fever and a high case fatality rate for which there are no licensed vaccines or therapeutics available. This natural history study consisted of twelve cynomolgus macaques challenged with 1000 PFU of MARV Angola and observed for body weight, temperature, viremia, hematology, clinical chemistry, and coagulation at multiple time points. All animals succumbed to disease within 8 days and exhibited signs consistent with those observed in human cases, including viremia, fever, systemic inflammation, coagulopathy, and lymphocytolysis, among others. Additionally, this study determined the time from exposure to onset of disease manifestations and the time course, frequency, and magnitude of the manifestations. This study will be instrumental in the design and development of medical countermeasures to Marburg virus disease

Poetry as praxis: An exploration of poetry discourse as qualitative inquiry

To capture the essence of an experience, poetry as research may manifest itself in two ways: (i) creating a research poem from existing data, often transcripts, or (ii) using participants\u27 poetry as a data-set for harvesting patterns and themes. This research focuses on the second form of poetic inquiry as a means of praxis by using the poetry of inservice teachers, preservice teachers, and elementary students to discover themes in regard to the teaching and learning process. As literacy teacher educators, creating praxis (moving from the theoretical to the practical) remains the ultimate goal of teaching and learning experiences. We gathered poems as data-sets in order to explore the possible benefits and limitations of poetic inquiry. As we approached the notion of poetry as a form of inquiry, we probed whether this art-based inquiry might also equate educational praxis. After considering several poetry data-sets, this research provides evidence of possible benefits related to the praxis that poetry as discourse and artistic inquiry affords, and presents the caveats of the research by identifying possible limitations